| Regulatory T cells in cancer immunotherapy A Tanaka, S Sakaguchi Cell research 27 (1), 109-118, 2017 | 1731 | 2017 |
| PD-1+ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer T Kamada, Y Togashi, C Tay, D Ha, A Sasaki, Y Nakamura, E Sato, ... Proceedings of the National Academy of Sciences 116 (20), 9999-10008, 2019 | 923 | 2019 |
| Regulatory T cells and human disease S Sakaguchi, N Mikami, JB Wing, A Tanaka, K Ichiyama, N Ohkura Annual Review of Immunology 38, 541-566, 2020 | 917 | 2020 |
| T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development N Ohkura, M Hamaguchi, H Morikawa, K Sugimura, A Tanaka, Y Ito, ... Immunity 37 (5), 785-799, 2012 | 841 | 2012 |
| Human FOXP3+ regulatory T cell heterogeneity and function in autoimmunity and cancer JB Wing, A Tanaka, S Sakaguchi Immunity 50 (2), 302-316, 2019 | 643 | 2019 |
| Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax) JD Leverson, H Zhang, J Chen, SK Tahir, DC Phillips, J Xue, P Nimmer, ... Cell death & disease 6 (1), e1590-e1590, 2015 | 507 | 2015 |
| Targeting Treg cells in cancer immunotherapy A Tanaka, S Sakaguchi European journal of immunology 49 (8), 1140-1146, 2019 | 444 | 2019 |
| Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy C Tay, A Tanaka, S Sakaguchi Cancer Cell 41 (3), 450-465, 2023 | 228 | 2023 |
| Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody D Ha, A Tanaka, T Kibayashi, A Tanemura, D Sugiyama, JB Wing, EL Lim, ... Proceedings of the National Academy of Sciences 116 (2), 609-618, 2019 | 202 | 2019 |
| Autoimmune Th17 cells induced synovial stromal and innate lymphoid cell secretion of the cytokine GM-CSF to initiate and augment autoimmune arthritis K Hirota, M Hashimoto, Y Ito, M Matsuura, H Ito, M Tanaka, H Watanabe, ... Immunity 48 (6), 1220-1232. e5, 2018 | 177 | 2018 |
| Somatic hypermutation and class switch recombination in Msh6−/− Ung−/− double-knockout mice HM Shen, A Tanaka, G Bozek, D Nicolae, U Storb The Journal of Immunology 177 (8), 5386-5392, 2006 | 145 | 2006 |
| CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory Y Kidani, W Nogami, Y Yasumizu, A Kawashima, A Tanaka, Y Sonoda, ... Proceedings of the National Academy of Sciences 119 (7), e2114282119, 2022 | 132 | 2022 |
| Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function S Tanaka, S Maeda, M Hashimoto, C Fujimori, Y Ito, S Teradaira, K Hirota, ... The Journal of Immunology 185 (4), 2295-2305, 2010 | 123 | 2010 |
| Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease Y Ito, M Hashimoto, K Hirota, N Ohkura, H Morikawa, H Nishikawa, ... Science 346 (6207), 363-368, 2014 | 101 | 2014 |
| Regulatory T cell-specific epigenomic region variants are a key determinant of susceptibility to common autoimmune diseases N Ohkura, Y Yasumizu, Y Kitagawa, A Tanaka, Y Nakamura, D Motooka, ... Immunity 52 (6), 1119-1132. e4, 2020 | 100 | 2020 |
| PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment D Thumkeo, S Punyawatthananukool, S Prasongtanakij, R Matsuura, ... Cell Reports 39 (10), 110914, 2022 | 86 | 2022 |
| Tyrosine kinase inhibitor imatinib augments tumor immunity by depleting effector regulatory T cells A Tanaka, H Nishikawa, S Noguchi, D Sugiyama, H Morikawa, ... Journal of Experimental Medicine 217 (2), 2020 | 80 | 2020 |
| The very 5′ end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions S Longerich, A Tanaka, G Bozek, D Nicolae, U Storb The Journal of experimental medicine 202 (10), 1443-1454, 2005 | 74 | 2005 |
| Attracting AID to targets of somatic hypermutation A Tanaka, HM Shen, S Ratnam, P Kodgire, U Storb Journal of Experimental Medicine 207 (2), 405-415, 2010 | 71 | 2010 |
| Thymus, innate immunity and autoimmune arthritis: interplay of gene and environment S Sakaguchi, S Tanaka, A Tanaka, Y Ito, S Maeda, N Sakaguchi, ... Febs Letters 585 (23), 3633-3639, 2011 | 21 | 2011 |
