Следене
Ahmed Hassan Abdelazeem
Ahmed Hassan Abdelazeem
Professor of Medicinal Chemistry & Drug Design, Faculty of Pharmacy, Beni-Suef University, Egypt
Потвърден имейл адрес: pharm.bsu.edu.eg - Начална страница
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Позовавания
Позовавания
Година
A comprehensive overview of globally approved JAK inhibitors
AM Shawky, FA Almalki, AN Abdalla, AH Abdelazeem, AM Gouda
Pharmaceutics 14 (5), 1001, 2022
1912022
Synthesis, anticancer activity and molecular modeling studies of 1, 2, 4-triazole derivatives as EGFR inhibitors
HAM El-Sherief, BGM Youssif, SNA Bukhari, AH Abdelazeem, ...
European journal of medicinal chemistry 156, 774-789, 2018
1852018
Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents
AH Abdelazeem, SA Abdelatef, MT El-Saadi, HA Omar, SI Khan, ...
European Journal of Pharmaceutical Sciences 62, 197-211, 2014
862014
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino [1, 2-a] indol-1 (2H)-ones as potential anticancer …
BGM Youssif, MH Abdelrahman, AH Abdelazeem, HM Ibrahim, OIA Salem, ...
European Journal of Medicinal Chemistry 146, 260-273, 2018
742018
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance
GF Zha, HL Qin, BGM Youssif, MW Amjad, MAG Raja, AH Abdelazeem, ...
European Journal of Medicinal Chemistry 135, 34-48, 2017
702017
Wasp venom biochemical components and their potential in biological applications and nanotechnological interventions
A Abd El-Wahed, N Yosri, HH Sakr, M Du, AFM Algethami, C Zhao, ...
Toxins 13 (3), 206, 2021
622021
Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory …
MH Abdelrahman, BGM Youssif, AH Abdelazeem, HM Ibrahim, ...
European Journal of Medicinal Chemistry 127, 972-985, 2017
612017
Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity
FAM Mohamed, HAM Gomaa, OM Hendawy, AT Ali, HS Farghaly, ...
Bioorganic Chemistry 112, 104960, 2021
592021
Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities
AH Abdelazeem, MT El-Saadi, EG Said, BGM Youssif, HA Omar, ...
Bioorganic Chemistry 75, 127-138, 2017
522017
Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile
AH Abdelazeem, MT El-Saadi, AGS El-Din, HA Omar, SM El-Moghazy
Bioorganic & medicinal chemistry 25 (2), 665-676, 2017
502017
Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents
AH Abdelazeem, AM Gouda, HA Omar, MF Tolba
Bioorganic Chemistry 57, 132-141, 2014
502014
Design, synthesis and anticancer evaluation of novel spirobenzo [h] chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities
SA Abdelatef, MT El-Saadi, NH Amin, AH Abdelazeem, HA Omar, ...
European journal of medicinal chemistry 150, 567-578, 2018
472018
Design, synthesis and pharmacological evaluation of novel pyrrolizine derivatives as potential anticancer agents
AM Gouda, AH Abdelazeem, ESA Arafa, KRA Abdellatif
Bioorganic chemistry 53, 1-7, 2014
452014
An integrated overview on pyrrolizines as potential anti-inflammatory, analgesic and antipyretic agents
AM Gouda, AH Abdelazeem
European Journal of Medicinal Chemistry 114, 257-292, 2016
412016
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents
AH Abdelazeem, SI Khan, SW White, KJ Sufka, CR McCurdy
Bioorganic & medicinal chemistry 23 (13), 3248-3259, 2015
392015
OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro
EA Arafa, AH Abdelazeem, HH Arab, HA Omar
Acta Pharmacologica Sinica 35 (3), 394-400, 2014
392014
Design, synthesis, and biological evaluation of some novel pyrrolizine derivatives as COX inhibitors with anti-inflammatory/analgesic activities and low ulcerogenic liability
AM Gouda, HI Ali, WH Almalki, MA Azim, MAS Abourehab, ...
Molecules 21 (2), 201, 2016
362016
Synthesis and pharmacological characterization of a novel sigma receptor ligand with improved metabolic stability and antagonistic effects against methamphetamine
MJ Seminerio, MJ Robson, AH Abdelazeem, C Mesangeau, ...
The AAPS journal 14, 43-51, 2012
362012
Synthesis, biological evaluation and kinase profiling of novel S-benzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazole derivatives as cytotoxic agents with apoptosis-inducing activity
AH Abdelazeem, AM Alqahtani, HA Omar, SNA Bukhari, AM Gouda
Journal of Molecular Structure 1219, 128567, 2020
322020
Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks
AH Abdelazeem, AGS El-Din, MM Abdel-Fattah, NH Amin, ...
European Journal of Medicinal Chemistry 205, 112662, 2020
322020
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