Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ... Nature medicine 25 (4), 628-640, 2019 | 653 | 2019 |
Sonic hedgehog promotes desmoplasia in pancreatic cancer JM Bailey, BJ Swanson, T Hamada, JP Eggers, PK Singh, T Caffery, ... Clinical cancer research 14 (19), 5995-6004, 2008 | 645 | 2008 |
MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer SK Shukla, V Purohit, K Mehla, V Gunda, NV Chaika, E Vernucci, RJ King, ... Cancer Cell 32 (1), 71-87. e7, 2017 | 527 | 2017 |
Cell surface-associated mucins in signal transduction PK Singh, MA Hollingsworth Trends in cell biology 16 (9), 467-476, 2006 | 520 | 2006 |
Metabolic regulation of macrophage polarization in cancer K Mehla, PK Singh Trends in cancer 5 (12), 822-834, 2019 | 436 | 2019 |
Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins JM Bailey, PK Singh, MA Hollingsworth Journal of cellular biochemistry 102 (4), 829-839, 2007 | 298 | 2007 |
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia SK Shukla, T Gebregiworgis, V Purohit, NV Chaika, V Gunda, ... Cancer & metabolism 2 (1), 18, 2014 | 267 | 2014 |
Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism MP Torres, S Rachagani, V Purohit, P Pandey, S Joshi, ED Moore, ... Cancer letters 323 (1), 29-40, 2012 | 266 | 2012 |
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer NV Chaika, T Gebregiworgis, ME Lewallen, V Purohit, P Radhakrishnan, ... Proceedings of the National Academy of Sciences 109 (34), 13787-13792, 2012 | 244 | 2012 |
De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer S Tadros, SK Shukla, RJ King, V Gunda, E Vernucci, J Abrego, NV Chaika, ... Cancer Research 77 (20), 5503-5517, 2017 | 204 | 2017 |
MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells P Chaturvedi, AP Singh, S Chakraborty, SC Chauhan, S Bafna, JL Meza, ... Cancer research 68 (7), 2065-2070, 2008 | 199 | 2008 |
Nucleotide metabolism: a pan-cancer metabolic dependency NJ Mullen, PK Singh Nature Reviews Cancer, 1-20, 2023 | 182 | 2023 |
CRTC3 links catecholamine signalling to energy balance Y Song, J Altarejos, MO Goodarzi, H Inoue, X Guo, R Berdeaux, JH Kim, ... Nature 468 (7326), 933-939, 2010 | 182 | 2010 |
O-GlcNAc transferase suppresses inflammation and necroptosis by targeting receptor-interacting serine/threonine-protein kinase 3 X Li, W Gong, H Wang, T Li, KS Attri, RE Lewis, AC Kalil, F Bhinderwala, ... Immunity 50 (3), 576-590. e6, 2019 | 176 | 2019 |
The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition J Goodwin, ML Neugent, SY Lee, JH Choe, H Choi, DMR Jenkins, ... Nature communications 8 (1), 15503, 2017 | 165 | 2017 |
Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer V Coothankandaswamy, S Cao, Y Xu, PD Prasad, PK Singh, ... British Journal of Pharmacology 173 (23), 3292-3306, 2016 | 140 | 2016 |
Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis J Goodwin, H Choi, M Hsieh, ML Neugent, JM Ahn, HN Hayenga, ... American journal of respiratory cell and molecular biology 58 (2), 216-231, 2018 | 138 | 2018 |
Platelet-Derived Growth Factor Receptor β–Mediated Phosphorylation of MUC1 Enhances Invasiveness in Pancreatic Adenocarcinoma Cells PK Singh, Y Wen, BJ Swanson, K Shanmugam, A Kazlauskas, RL Cerny, ... Cancer research 67 (11), 5201-5210, 2007 | 138 | 2007 |
RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells H Tsutsumida, BJ Swanson, PK Singh, TC Caffrey, S Kitajima, M Goto, ... Clinical cancer research 12 (10), 2976-2987, 2006 | 136 | 2006 |
MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion BJ Swanson, KM McDermott, PK Singh, JP Eggers, PR Crocker, ... Cancer research 67 (21), 10222-10229, 2007 | 126 | 2007 |