Interpreting the language of histone and DNA modifications SB Rothbart, BD Strahl Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (8), 627-643, 2014 | 909 | 2014 |
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation SB Rothbart, K Krajewski, N Nady, W Tempel, S Xue, AI Badeaux, ... Nature structural & molecular biology 19 (11), 1155-1160, 2012 | 429 | 2012 |
Structural basis for DNMT3A-mediated de novo DNA methylation ZM Zhang, R Lu, P Wang, Y Yu, D Chen, L Gao, S Liu, D Ji, SB Rothbart, ... Nature 554 (7692), 387-391, 2018 | 308 | 2018 |
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting L Cai, SB Rothbart, R Lu, B Xu, WY Chen, A Tripathy, S Rockowitz, ... Molecular cell 49 (3), 571-582, 2013 | 281 | 2013 |
A DNA methylation reader complex that enhances gene transcription CJ Harris, M Scheibe, SP Wongpalee, W Liu, EM Cornett, RM Vaughan, ... Science 362 (6419), 1182-1186, 2018 | 223 | 2018 |
Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation SB Rothbart, BM Dickson, MS Ong, K Krajewski, S Houliston, DB Kireev, ... Genes & development 27 (11), 1288-1298, 2013 | 201 | 2013 |
A histone methylation network regulates transgenerational epigenetic memory in C. elegans EL Greer, SE Beese-Sims, E Brookes, R Spadafora, Y Zhu, SB Rothbart, ... Cell reports 7 (1), 113-126, 2014 | 191 | 2014 |
Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition AC Racanelli, SB Rothbart, CL Heyer, RG Moran Cancer research 69 (13), 5467-5474, 2009 | 187 | 2009 |
An interactive database for the assessment of histone antibody specificity SB Rothbart, BM Dickson, JR Raab, AT Grzybowski, K Krajewski, AH Guo, ... Molecular cell 59 (3), 502-511, 2015 | 181 | 2015 |
The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers BJ Klein, L Piao, Y Xi, H Rincon-Arano, SB Rothbart, D Peng, H Wen, ... Cell reports 6 (2), 325-335, 2014 | 179 | 2014 |
Neuronal stress pathway mediating a histone methyl/phospho switch is required for herpes simplex virus reactivation AR Cliffe, JH Arbuckle, JL Vogel, MJ Geden, SB Rothbart, CL Cusack, ... Cell host & microbe 18 (6), 649-658, 2015 | 169 | 2015 |
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 JS Harrison, EM Cornett, D Goldfarb, PA DaRosa, ZM Li, F Yan, ... Elife 5, e17101, 2016 | 153 | 2016 |
Histone H3. 3 phosphorylation amplifies stimulation-induced transcription A Armache, S Yang, A Martínez de Paz, LE Robbins, C Durmaz, ... Nature 583 (7818), 852-857, 2020 | 132 | 2020 |
Defining UHRF1 domains that support maintenance of human colon cancer DNA methylation and oncogenic properties X Kong, J Chen, W Xie, SM Brown, Y Cai, K Wu, D Fan, Y Nie, ... Cancer cell 35 (4), 633-648. e7, 2019 | 122 | 2019 |
Examining the roles of H3K4 methylation states with systematically characterized antibodies RN Shah, AT Grzybowski, EM Cornett, AL Johnstone, BM Dickson, ... Molecular cell 72 (1), 162-177. e7, 2018 | 122 | 2018 |
Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas SB Rothbart, AC Racanelli, RG Moran Cancer research 70 (24), 10299-10309, 2010 | 117 | 2010 |
An allosteric interaction links USP7 to deubiquitination and chromatin targeting of UHRF1 ZM Zhang, SB Rothbart, DF Allison, Q Cai, JS Harrison, L Li, Y Wang, ... Cell reports 12 (9), 1400-1406, 2015 | 114 | 2015 |
AMP-activated protein kinase (AMPK) control of mTORC1 is p53-and TSC2-independent in pemetrexed-treated carcinoma cells S Agarwal, CM Bell, SB Rothbart, RG Moran Journal of Biological Chemistry 290 (46), 27473-27486, 2015 | 109 | 2015 |
Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin M Ali, K Yan, ME Lalonde, C Degerny, SB Rothbart, BD Strahl, J Côté, ... Journal of molecular biology 424 (5), 328-338, 2012 | 108 | 2012 |
Lysine methylation regulators moonlighting outside the epigenome EM Cornett, L Ferry, PA Defossez, SB Rothbart Molecular cell 75 (6), 1092-1101, 2019 | 102 | 2019 |