Следене
Charlie Hatton
Charlie Hatton
Dana-Farber Cancer Institute
Потвърден имейл адрес: dfci.harvard.edu
Заглавие
Позовавания
Позовавания
Година
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
83422012
Recurrent BRAF mutations in Langerhans cell histiocytosis
G Badalian-Very, JA Vergilio, BA Degar, LE MacConaill, B Brandner, ...
Blood, The Journal of the American Society of Hematology 116 (11), 1919-1923, 2010
13162010
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ...
Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007
12642007
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
11762007
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy
J Barretina, BS Taylor, S Banerji, AH Ramos, M Lagos-Quintana, ...
Nature genetics 42 (8), 715-721, 2010
8182010
MEK1 mutations confer resistance to MEK and B-RAF inhibition
CM Emery, KG Vijayendran, MC Zipser, AM Sawyer, L Niu, JJ Kim, ...
Proceedings of the National Academy of Sciences 106 (48), 20411-20416, 2009
7992009
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
CA Lovejoy, W Li, S Reisenweber, S Thongthip, J Bruno, T De Lange, ...
PLoS genetics 8 (7), e1002772, 2012
6532012
Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
PS Hammerman, ML Sos, AH Ramos, C Xu, A Dutt, W Zhou, LE Brace, ...
Cancer discovery 1 (1), 78-89, 2011
5982011
Drug-sensitive FGFR2 mutations in endometrial carcinoma
A Dutt, HB Salvesen, TH Chen, AH Ramos, RC Onofrio, C Hatton, ...
Proceedings of the National Academy of Sciences 105 (25), 8713-8717, 2008
4252008
Profiling critical cancer gene mutations in clinical tumor samples
LE MacConaill, CD Campbell, SM Kehoe, AJ Bass, C Hatton, L Niu, ...
PloS one 4 (11), e7887, 2009
3722009
A menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia
AV Krivtsov, K Evans, JY Gadrey, BK Eschle, C Hatton, HJ Uckelmann, ...
Cancer cell 36 (6), 660-673. e11, 2019
3542019
Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia
HJ Uckelmann, SM Kim, EM Wong, C Hatton, H Giovinazzo, JY Gadrey, ...
Science 367 (6477), 586-590, 2020
2192020
EZH2 inhibitor efficacy in non-Hodgkin’s lymphoma does not require suppression of H3K27 monomethylation
WD Bradley, S Arora, J Busby, S Balasubramanian, VS Gehling, ...
Chemistry & biology 21 (11), 1463-1475, 2014
1722014
An alternative approach to ChIP-Seq normalization enables detection of genome-wide changes in histone H3 lysine 27 trimethylation upon EZH2 inhibition
B Egan, CC Yuan, ML Craske, P Labhart, GD Guler, D Arnott, TM Maile, ...
PloS one 11 (11), e0166438, 2016
1622016
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
AR Conery, RC Centore, A Neiss, PJ Keller, S Joshi, KL Spillane, ...
Elife 5, e10483, 2016
1312016
MEN1 mutations mediate clinical resistance to menin inhibition
F Perner, EM Stein, DV Wenge, S Singh, J Kim, A Apazidis, ...
Nature 615 (7954), 913-919, 2023
1222023
The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML
EB Heikamp, JA Henrich, F Perner, EM Wong, C Hatton, Y Wen, ...
Blood, The Journal of the American Society of Hematology 139 (6), 894-906, 2022
1122022
Pharmacological inhibition of the histone lysine demethylase KDM1A suppresses the growth of multiple acute myeloid leukemia subtypes
JP McGrath, KE Williamson, S Balasubramanian, S Odate, S Arora, ...
Cancer research 76 (7), 1975-1988, 2016
1052016
High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade
MK Kießling, PA Oberholzer, C Mondal, MB Karpova, MC Zipser, WM Lin, ...
Blood, The Journal of the American Society of Hematology 117 (8), 2433-2440, 2011
1052011
Prospective enterprise-level molecular genotyping of a cohort of cancer patients
LE MacConaill, E Garcia, P Shivdasani, M Ducar, R Adusumilli, ...
The Journal of Molecular Diagnostics 16 (6), 660-672, 2014
932014
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Статии 1–20