| Identification and characterization of a novel botulinum neurotoxin S Zhang, G Masuyer, J Zhang, Y Shen, D Lundin, L Henriksson, ... Nature communications 8 (1), 14130, 2017 | 279 | 2017 |
| Rho-kinase: regulation,(dys) function, and inhibition E Amin, BN Dubey, SC Zhang, L Gremer, R Dvorsky, JM Moll, MS Taha, ... Biological chemistry 394 (11), 1399-1410, 2013 | 207 | 2013 |
| Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis E Flex, M Jaiswal, F Pantaleoni, S Martinelli, M Strullu, EK Fansa, A Caye, ... Human molecular genetics 23 (16), 4315-4327, 2014 | 180 | 2014 |
| Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium S Zhang, F Lebreton, MJ Mansfield, SI Miyashita, J Zhang, ... Cell host & microbe 23 (2), 169-176. e6, 2018 | 166 | 2018 |
| N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A G Yao, S Zhang, S Mahrhold, K Lam, D Stern, K Bagramyan, K Perry, ... Nature structural & molecular biology 23 (7), 656-662, 2016 | 126 | 2016 |
| Critical off‐target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets S Dütting, J Heidenreich, D Cherpokova, E Amin, SC Zhang, ... Journal of Thrombosis and Haemostasis 13 (5), 827-838, 2015 | 90 | 2015 |
| Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity TR Blum, H Liu, MS Packer, X Xiong, PG Lee, S Zhang, M Richter, ... Science 371 (6531), 803-810, 2021 | 71 | 2021 |
| Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin NJ Huang, N Pishesha, J Mukherjee, S Zhang, R Deshycka, V Sudaryo, ... Nature Communications 8 (1), 423, 2017 | 58 | 2017 |
| Delivery of single-domain antibodies into neurons using a chimeric toxin–based platform is therapeutic in mouse models of botulism SI Miyashita, J Zhang, S Zhang, CB Shoemaker, M Dong Science Translational Medicine 13 (575), eaaz4197, 2021 | 52 | 2021 |
| Structural characterisation of the catalytic domain of botulinum neurotoxin X-high activity and unique substrate specificity G Masuyer, S Zhang, S Barkho, Y Shen, L Henriksson, S Košenina, ... Scientific reports 8 (1), 4518, 2018 | 49 | 2018 |
| Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes IC Cirstea, L Gremer, R Dvorsky, SC Zhang, RP Piekorz, M Zenker, ... Human molecular genetics 22 (2), 262-270, 2013 | 49 | 2013 |
| Bioinformatic discovery of a toxin family in Chryseobacterium piperi with sequence similarity to botulinum neurotoxins MJ Mansfield, TG Wentz, S Zhang, EJ Lee, M Dong, SK Sharma, ... Scientific reports 9 (1), 1634, 2019 | 36 | 2019 |
| Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC S Zhang, RPA Berntsson, WH Tepp, L Tao, EA Johnson, P Stenmark, ... Nature communications 8 (1), 1637, 2017 | 35 | 2017 |
| Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models M Elliott, C Favre-Guilmard, SM Liu, J Maignel, G Masuyer, M Beard, ... Science advances 5 (1), eaau7196, 2019 | 33 | 2019 |
| Structure analysis of a new psychrophilic marine protease SC Zhang, M Sun, T Li, QH Wang, JH Hao, Y Han, XJ Hu, M Zhou, SX Lin PLoS One 6 (11), e26939, 2011 | 31 | 2011 |
| Crystal structure of botulinum neurotoxin A2 in complex with the human protein receptor SV2C reveals plasticity in receptor binding R Gustafsson, S Zhang, G Masuyer, M Dong, P Stenmark Toxins 10 (4), 153, 2018 | 26 | 2018 |
| Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy L Yin, G Masuyer, S Zhang, J Zhang, SI Miyashita, D Burgin, L Lovelock, ... PLoS biology 18 (3), e3000618, 2020 | 21 | 2020 |
| Single domain antibody application in bacterial infection diagnosis and neutralization Q Qin, H Liu, W He, Y Guo, J Zhang, J She, F Zheng, S Zhang, ... Frontiers in Immunology 13, 1014377, 2022 | 20 | 2022 |
| Interaction characteristics of Plexin-B1 with Rho family proteins EK Fansa, R Dvorsky, SC Zhang, D Fiegen, MR Ahmadian Biochemical and biophysical research communications 434 (4), 785-790, 2013 | 20 | 2013 |
| Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1 SC Zhang, L Gremer, H Heise, P Janning, A Shymanets, IC Cirstea, ... PLoS One 9 (7), e102425, 2014 | 18 | 2014 |
