| HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells LZ Shi, R Wang, G Huang, P Vogel, G Neale, DR Green, H Chi Journal of Experimental Medicine 208 (7), 1367-1376, 2011 | 1915 | 2011 |
| Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... Cell 184 (1), 149-168. e17, 2021 | 1404 | 2021 |
| The genomic landscape of hypodiploid acute lymphoblastic leukemia L Holmfeldt, L Wei, E Diaz-Flores, M Walsh, J Zhang, L Ding, ... Nature genetics 45 (3), 242-252, 2013 | 845 | 2013 |
| mTORC1 couples immune signals and metabolic programming to establish T reg-cell function H Zeng, K Yang, C Cloer, G Neale, P Vogel, H Chi Nature 499 (7459), 485-490, 2013 | 826 | 2013 |
| Inflammasome is a central player in the induction of obesity and insulin resistance R Stienstra, JA Van Diepen, CJ Tack, MH Zaki, FL Van De Veerdonk, ... Proceedings of the National Academy of Sciences 108 (37), 15324-15329, 2011 | 811 | 2011 |
| ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways T Kuriakose, SM Man, RK Subbarao Malireddi, R Karki, S Kesavardhana, ... Science immunology 1 (2), aag2045-aag2045, 2016 | 675 | 2016 |
| Germline genomic variants associated with childhood acute lymphoblastic leukemia LR Treviño, W Yang, D French, SP Hunger, WL Carroll, M Devidas, ... Nature genetics 41 (9), 1001-1005, 2009 | 619 | 2009 |
| Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis J Wei, L Long, K Yang, C Guy, S Shrestha, Z Chen, C Wu, P Vogel, ... Nature immunology 17 (3), 277-285, 2016 | 449 | 2016 |
| T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming K Yang, S Shrestha, H Zeng, PWF Karmaus, G Neale, P Vogel, ... Immunity 39 (6), 1043-1056, 2013 | 412 | 2013 |
| Cross-species genomics matches driver mutations and cell compartments to model ependymoma RA Johnson, KD Wright, H Poppleton, KM Mohankumar, D Finkelstein, ... Nature 466 (7306), 632-636, 2010 | 398 | 2010 |
| T reg cells require the phosphatase PTEN to restrain TH 1 and T FH cell responses S Shrestha, K Yang, C Guy, P Vogel, G Neale, H Chi Nature immunology 16 (2), 178-187, 2015 | 381 | 2015 |
| The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection SM Man, R Karki, RKS Malireddi, G Neale, P Vogel, M Yamamoto, ... Nature immunology 16 (5), 467-475, 2015 | 376 | 2015 |
| Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse V Perez-Andreu, KG Roberts, RC Harvey, W Yang, C Cheng, D Pei, H Xu, ... Nature genetics 45 (12), 1494-1498, 2013 | 354 | 2013 |
| mTORC1 and mTORC2 kinase signaling and glucose metabolism drive follicular helper T cell differentiation HU Zeng, S Cohen, C Guy, S Shrestha, G Neale, SA Brown, C Cloer, ... Immunity 45 (3), 540-554, 2016 | 344 | 2016 |
| Critical role for the DNA sensor AIM2 in stem cell proliferation and cancer SM Man, Q Zhu, L Zhu, Z Liu, R Karki, A Malik, D Sharma, L Li, ... Cell 162 (1), 45-58, 2015 | 343 | 2015 |
| The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function K Yang, G Neale, DR Green, W He, H Chi Nature immunology 12 (9), 888-897, 2011 | 315 | 2011 |
| IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11-NLRP3 inflammasomes SM Man, R Karki, M Sasai, DE Place, S Kesavardhana, J Temirov, ... Cell 167 (2), 382-396. e17, 2016 | 308 | 2016 |
| E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification DT Huang, O Ayrault, HW Hunt, AM Taherbhoy, DM Duda, DC Scott, ... Molecular cell 33 (4), 483-495, 2009 | 296 | 2009 |
| TNF counterbalances the emergence of M2 tumor macrophages F Kratochvill, G Neale, JM Haverkamp, LA Van de Velde, AM Smith, ... Cell reports 12 (11), 1902-1914, 2015 | 287 | 2015 |
| Pharmacokinetic, pharmacodynamic, and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia JD Kawedia, SC Kaste, D Pei, JC Panetta, X Cai, C Cheng, G Neale, ... Blood, The Journal of the American Society of Hematology 117 (8), 2340-2347, 2011 | 285 | 2011 |
