The impact of microRNAs on protein output D Baek, J Villén, C Shin, FD Camargo, SP Gygi, DP Bartel Nature 455 (7209), 64-71, 2008 | 4512 | 2008 |
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer K Rikova, A Guo, Q Zeng, A Possemato, J Yu, H Haack, J Nardone, K Lee, ... Cell 131 (6), 1190-1203, 2007 | 2800 | 2007 |
A quantitative atlas of mitotic phosphorylation N Dephoure, C Zhou, J Villén, SA Beausoleil, CE Bakalarski, SJ Elledge, ... Proceedings of the National Academy of Sciences 105 (31), 10762-10767, 2008 | 1976 | 2008 |
A tissue-specific atlas of mouse protein phosphorylation and expression EL Huttlin, MP Jedrychowski, JE Elias, T Goswami, R Rad, SA Beausoleil, ... Cell 143 (7), 1174-1189, 2010 | 1889 | 2010 |
A probability-based approach for high-throughput protein phosphorylation analysis and site localization SA Beausoleil, J Villén, SA Gerber, J Rush, SP Gygi Nature biotechnology 24 (10), 1285-1292, 2006 | 1759 | 2006 |
Large-scale characterization of HeLa cell nuclear phosphoproteins SA Beausoleil, M Jedrychowski, D Schwartz, JE Elias, J Villén, J Li, ... Proceedings of the National Academy of Sciences 101 (33), 12130-12135, 2004 | 1722 | 2004 |
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution LJ Holt, BB Tuch, J Villén, AD Johnson, SP Gygi, DO Morgan Science 325 (5948), 1682-1686, 2009 | 1064 | 2009 |
Angiogenin-induced tRNA fragments inhibit translation initiation P Ivanov, MM Emara, J Villen, SP Gygi, P Anderson Molecular cell 43 (4), 613-623, 2011 | 1007 | 2011 |
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling Y Yu, SO Yoon, G Poulogiannis, Q Yang, XM Ma, J Villén, N Kubica, ... Science 332 (6035), 1322-1326, 2011 | 994 | 2011 |
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span MK Lehtinen, Z Yuan, PR Boag, Y Yang, J Villén, EBE Becker, S DiBacco, ... Cell 125 (5), 987-1001, 2006 | 986 | 2006 |
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans EL Greer, D Dowlatshahi, MR Banko, J Villen, K Hoang, D Blanchard, ... Current biology 17 (19), 1646-1656, 2007 | 938 | 2007 |
Large-scale phosphorylation analysis of mouse liver J Villén, SA Beausoleil, SA Gerber, SP Gygi Proceedings of the National Academy of Sciences 104 (5), 1488-1493, 2007 | 854 | 2007 |
The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry J Villén, SP Gygi Nature protocols 3 (10), 1630-1638, 2008 | 743 | 2008 |
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation DL Swaney, P Beltrao, L Starita, A Guo, J Rush, S Fields, NJ Krogan, ... Nature methods 10 (7), 676-682, 2013 | 719 | 2013 |
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues SW Eichhorn, H Guo, SE McGeary, RA Rodriguez-Mias, C Shin, D Baek, ... Molecular cell 56 (1), 104-115, 2014 | 638 | 2014 |
Signaling networks assembled by oncogenic EGFR and c-Met A Guo, J Villén, J Kornhauser, KA Lee, MP Stokes, K Rikova, ... Proceedings of the National Academy of Sciences 105 (2), 692-697, 2008 | 609 | 2008 |
Chromatogram libraries improve peptide detection and quantification by data independent acquisition mass spectrometry BC Searle, LK Pino, JD Egertson, YS Ting, RT Lawrence, BX MacLean, ... Nature communications 9 (1), 5128, 2018 | 497 | 2018 |
Systematic functional prioritization of protein posttranslational modifications P Beltrao, V Albanèse, LR Kenner, DL Swaney, A Burlingame, J Villén, ... Cell 150 (2), 413-425, 2012 | 462 | 2012 |
Phosphoproteomic analysis of the developing mouse brain BA Ballif, J Villen, SA Beausoleil, D Schwartz, SP Gygi Molecular & Cellular Proteomics 3 (11), 1093-1101, 2004 | 422 | 2004 |
Large-Scale Phosphorylation Analysis of α-Factor-Arrested Saccharomyces cerevisiae X Li, SA Gerber, AD Rudner, SA Beausoleil, W Haas, J Villen, JE Elias, ... Journal of proteome research 6 (3), 1190-1197, 2007 | 381 | 2007 |