Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity H Manya, A Chiba, A Yoshida, X Wang, Y Chiba, Y Jigami, RU Margolis, ... Proceedings of the National Academy of Sciences 101 (2), 500-505, 2004 | 426 | 2004 |
Inhibition of tumor cell-induced platelet aggregation using a novel anti-podoplanin antibody reacting with its platelet-aggregation-stimulating domain Y Kato, MK Kaneko, A Kuno, N Uchiyama, K Amano, Y Chiba, ... Biochemical and biophysical research communications 349 (4), 1301-1307, 2006 | 277 | 2006 |
Production of human compatible high mannose-type (Man5GlcNAc2) sugar chains in Saccharomyces cerevisiae Y Chiba, M Suzuki, S Yoshida, A Yoshida, H Ikenaga, M Takeuchi, ... Journal of Biological Chemistry 273 (41), 26298-26304, 1998 | 209 | 1998 |
Molecular cloning and identification of 3′-phosphoadenosine 5′-phosphosulfate transporter S Kamiyama, T Suda, R Ueda, M Suzuki, R Okubo, N Kikuchi, Y Chiba, ... Journal of Biological Chemistry 278 (28), 25958-25963, 2003 | 172 | 2003 |
Comparison of the effects of agalsidase alfa and agalsidase beta on cultured human Fabry fibroblasts and Fabry mice H Sakuraba, M Murata-Ohsawa, I Kawashima, Y Tajima, M Kotani, ... Journal of human genetics 51 (3), 180-188, 2006 | 147 | 2006 |
Focused differential glycan analysis with the platform antibody-assisted lectin profiling for glycan-related biomarker verification A Kuno, Y Kato, A Matsuda, MK Kaneko, H Ito, K Amano, Y Chiba, ... Molecular & Cellular Proteomics 8 (1), 99-108, 2009 | 141 | 2009 |
Functional glycosylation of human podoplanin: glycan structure of platelet aggregation-inducing factor MK Kaneko, Y Kato, A Kameyama, H Ito, A Kuno, J Hirabayashi, T Kubota, ... FEBS letters 581 (2), 331-336, 2007 | 129 | 2007 |
Engineering of mucin-type human glycoproteins in yeast cells K Amano, Y Chiba, Y Kasahara, Y Kato, MK Kaneko, A Kuno, H Ito, ... Proceedings of the National Academy of Sciences 105 (9), 3232-3237, 2008 | 107 | 2008 |
Highly phosphomannosylated enzyme replacement therapy for GM2 gangliosidosis D Tsuji, H Akeboshi, K Matsuoka, H Yasuoka, E Miyasaki, Y Kasahara, ... Annals of neurology 69 (4), 691-701, 2011 | 104 | 2011 |
Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter N Ishida, S Yoshioka, Y Chiba, M Takeuchi, M Kawakita The journal of biochemistry 126 (1), 68-77, 1999 | 93 | 1999 |
Functional characterization of the Hansenula polymorpha HOC1, OCH1, and OCR1 genes as members of the yeast OCH1 mannosyltransferase family involved in protein glycosylation MW Kim, EJ Kim, JY Kim, JS Park, DB Oh, Y Shimma, Y Chiba, Y Jigami, ... Journal of Biological Chemistry 281 (10), 6261-6272, 2006 | 84 | 2006 |
Glycan engineering and production of ‘humanized’glycoprotein in yeast cells Y Chiba, H Akeboshi Biological and Pharmaceutical Bulletin 32 (5), 786-795, 2009 | 76 | 2009 |
A new β-1, 2-N-acetylglucosaminyltransferase that may play a role in the biosynthesis of mammalian O-mannosyl glycans S Takahashi, T Sasaki, H Manya, Y Chiba, A Yoshida, M Mizuno, ... Glycobiology 11 (1), 37-45, 2001 | 75 | 2001 |
Use of a modified α-N-acetylgalactosaminidase in the development of enzyme replacement therapy for Fabry disease Y Tajima, I Kawashima, T Tsukimura, K Sugawara, M Kuroda, T Suzuki, ... The American Journal of Human Genetics 85 (5), 569-580, 2009 | 71 | 2009 |
Production of recombinant β-hexosaminidase A, a potential enzyme for replacement therapy for Tay-Sachs and Sandhoff diseases, in the methylotrophic yeast Ogataea minuta H Akeboshi, Y Chiba, Y Kasahara, M Takashiba, Y Takaoka, M Ohsawa, ... Applied and environmental microbiology 73 (15), 4805-4812, 2007 | 69 | 2007 |
Production of humanized glycoproteins in bacteria and yeasts Y Chiba, Y Jigami Current opinion in chemical biology 11 (6), 670-676, 2007 | 68 | 2007 |
Molecular and enzymic properties of recombinant 1, 2-α-mannosidase from Aspergillus saitoi overexpressed in Aspergillus oryzae cells E Ichishima, N Taya, M Ikeguchi, Y Chiba, M Nakamura, C Kawabata, ... Biochemical Journal 339 (3), 589-597, 1999 | 66 | 1999 |
Physiological and glycomic characterization of N-acetylglucosaminyltransferase-IVa and -IVb double deficient mice S Takamatsu, A Antonopoulos, K Ohtsubo, D Ditto, Y Chiba, DT Le, ... Glycobiology 20 (4), 485-497, 2010 | 64 | 2010 |
Production in yeast of α-galactosidase A, a lysosomal enzyme applicable to enzyme replacement therapy for Fabry disease Y Chiba, H Sakuraba, M Kotani, R Kase, K Kobayashi, M Takeuchi, ... Glycobiology 12 (12), 821-828, 2002 | 64 | 2002 |
Characterization of yeast Yea4p, a uridine diphosphate-N-acetylglucosamine transporter localized in the endoplasmic reticulum and required for chitin synthesis SK Roy, Y Chiba, M Takeuchi, Y Jigami Journal of Biological Chemistry 275 (18), 13580-13587, 2000 | 61 | 2000 |