A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes ME MacDonald, CM Ambrose, MP Duyao, RH Myers, C Lin, L Srinidhi, ... Cell 72 (6), 971-983, 1993 | 7690 | 1993 |
Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q1 1.2–13.3 LM Brzustowicz, T Lehner, LH Castilla, GK Penchaszadeh, ... Nature 344 (6266), 540-541, 1990 | 785 | 1990 |
A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene: implications for presymptomatic testing and screening D Shattuck-Eidens, M McClure, J Simard, F Labrie, S Narod, F Couch, ... Jama 273 (7), 535-541, 1995 | 591 | 1995 |
Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer LH Castilla, FJ Couch, MR Erdos, KF Hoskins, K Calzone, JE Garber, ... Nature genetics 8 (4), 387-391, 1994 | 523 | 1994 |
Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein ɛ-deficient mice R Yamanaka, C Barlow, J Lekstrom-Himes, LH Castilla, PP Liu, ... Proceedings of the National Academy of Sciences 94 (24), 13187-13192, 1997 | 483 | 1997 |
Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5 X Yang, LH Castilla, X Xu, C Li, J Gotay, M Weinstein, PP Liu, CX Deng Development 126 (8), 1571-1580, 1999 | 473 | 1999 |
Genetic homogeneity between acute and chronic forms of spinal muscular atrophy TC Gilliam, LM Brzustowicz, LH Castilla, T Lehner, GK Penchaszadeh, ... Nature 345 (6278), 823-825, 1990 | 421 | 1990 |
Failure of Embryonic Hematopoiesis andLethal Hemorrhages in Mouse Embryos Heterozygousfor a Knocked-In Leukemia Gene CBFB–MYH11 LH Castilla, C Wijmenga, Q Wang, T Stacy, NA Speck, M Eckhaus, ... Cell 87 (4), 687-696, 1996 | 361 | 1996 |
The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia LH Castilla, L Garrett, N Adya, D Orlic, A Dutra, S Anderson, J Owens, ... Nature genetics 23 (2), 144-146, 1999 | 354 | 1999 |
ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data J Ou, H Liu, J Yu, MA Kelliher, LH Castilla, ND Lawson, LJ Zhu BMC genomics 19, 1-13, 2018 | 201 | 2018 |
Cbfβ-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia YH Kuo, SF Landrette, SA Heilman, PN Perrat, L Garrett, PP Liu, ... Cancer cell 9 (1), 57-68, 2006 | 182 | 2006 |
Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia LH Castilla, P Perrat, NJ Martinez, SF Landrette, R Keys, S Oikemus, ... Proceedings of the National Academy of Sciences 101 (14), 4924-4929, 2004 | 165 | 2004 |
Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11 SF Landrette, YH Kuo, K Hensen, ... Blood 105 (7), 2900-2907, 2005 | 150 | 2005 |
A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice A Illendula, JA Pulikkan, H Zong, J Grembecka, L Xue, S Sen, Y Zhou, ... Science 347 (6223), 779-784, 2015 | 132 | 2015 |
Small molecule inhibitor of CBFβ-RUNX binding for RUNX transcription factor driven cancers A Illendula, J Gilmour, J Grembecka, VSS Tirumala, A Boulton, ... EBioMedicine 8, 117-131, 2016 | 124 | 2016 |
Runx2 induces acute myeloid leukemia in cooperation with Cbfβ-SMMHC in mice YH Kuo, SK Zaidi, S Gornostaeva, T Komori, GS Stein, LH Castilla Blood, The Journal of the American Society of Hematology 113 (14), 3323-3332, 2009 | 110 | 2009 |
Function of CBFβ/Bro proteins N Adya, LH Castilla, PP Liu Seminars in cell & developmental biology 11 (5), 361-368, 2000 | 102 | 2000 |
CBFβ-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia JA Pulikkan, M Hegde, HM Ahmad, H Belaghzal, A Illendula, J Yu, ... Cell 174 (1), 172-186. e21, 2018 | 95 | 2018 |
Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11 M Kundu, A Chen, S Anderson, M Kirby, LP Xu, LH Castilla, D Bodine, ... Blood, The Journal of the American Society of Hematology 100 (7), 2449-2456, 2002 | 83 | 2002 |
Access to substance use treatment among young adults who use prescription opioids non-medically EJ Liebling, JL Yedinak, TC Green, SE Hadland, MA Clark, BDL Marshall Substance Abuse Treatment, Prevention, and Policy 11, 1-12, 2016 | 81 | 2016 |