Следене
lucio castilla
lucio castilla
Professor of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School
Потвърден имейл адрес: umassmed.edu
Заглавие
Позовавания
Позовавания
Година
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
ME MacDonald, CM Ambrose, MP Duyao, RH Myers, C Lin, L Srinidhi, ...
Cell 72 (6), 971-983, 1993
76901993
Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q1 1.2–13.3
LM Brzustowicz, T Lehner, LH Castilla, GK Penchaszadeh, ...
Nature 344 (6266), 540-541, 1990
7851990
A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene: implications for presymptomatic testing and screening
D Shattuck-Eidens, M McClure, J Simard, F Labrie, S Narod, F Couch, ...
Jama 273 (7), 535-541, 1995
5911995
Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer
LH Castilla, FJ Couch, MR Erdos, KF Hoskins, K Calzone, JE Garber, ...
Nature genetics 8 (4), 387-391, 1994
5231994
Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein ɛ-deficient mice
R Yamanaka, C Barlow, J Lekstrom-Himes, LH Castilla, PP Liu, ...
Proceedings of the National Academy of Sciences 94 (24), 13187-13192, 1997
4831997
Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5
X Yang, LH Castilla, X Xu, C Li, J Gotay, M Weinstein, PP Liu, CX Deng
Development 126 (8), 1571-1580, 1999
4731999
Genetic homogeneity between acute and chronic forms of spinal muscular atrophy
TC Gilliam, LM Brzustowicz, LH Castilla, T Lehner, GK Penchaszadeh, ...
Nature 345 (6278), 823-825, 1990
4211990
Failure of Embryonic Hematopoiesis andLethal Hemorrhages in Mouse Embryos Heterozygousfor a Knocked-In Leukemia Gene CBFB–MYH11
LH Castilla, C Wijmenga, Q Wang, T Stacy, NA Speck, M Eckhaus, ...
Cell 87 (4), 687-696, 1996
3611996
The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia
LH Castilla, L Garrett, N Adya, D Orlic, A Dutra, S Anderson, J Owens, ...
Nature genetics 23 (2), 144-146, 1999
3541999
ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data
J Ou, H Liu, J Yu, MA Kelliher, LH Castilla, ND Lawson, LJ Zhu
BMC genomics 19, 1-13, 2018
2012018
Cbfβ-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia
YH Kuo, SF Landrette, SA Heilman, PN Perrat, L Garrett, PP Liu, ...
Cancer cell 9 (1), 57-68, 2006
1822006
Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia
LH Castilla, P Perrat, NJ Martinez, SF Landrette, R Keys, S Oikemus, ...
Proceedings of the National Academy of Sciences 101 (14), 4924-4929, 2004
1652004
Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11
SF Landrette, YH Kuo, K Hensen, ...
Blood 105 (7), 2900-2907, 2005
1502005
A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice
A Illendula, JA Pulikkan, H Zong, J Grembecka, L Xue, S Sen, Y Zhou, ...
Science 347 (6223), 779-784, 2015
1322015
Small molecule inhibitor of CBFβ-RUNX binding for RUNX transcription factor driven cancers
A Illendula, J Gilmour, J Grembecka, VSS Tirumala, A Boulton, ...
EBioMedicine 8, 117-131, 2016
1242016
Runx2 induces acute myeloid leukemia in cooperation with Cbfβ-SMMHC in mice
YH Kuo, SK Zaidi, S Gornostaeva, T Komori, GS Stein, LH Castilla
Blood, The Journal of the American Society of Hematology 113 (14), 3323-3332, 2009
1102009
Function of CBFβ/Bro proteins
N Adya, LH Castilla, PP Liu
Seminars in cell & developmental biology 11 (5), 361-368, 2000
1022000
CBFβ-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia
JA Pulikkan, M Hegde, HM Ahmad, H Belaghzal, A Illendula, J Yu, ...
Cell 174 (1), 172-186. e21, 2018
952018
Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11
M Kundu, A Chen, S Anderson, M Kirby, LP Xu, LH Castilla, D Bodine, ...
Blood, The Journal of the American Society of Hematology 100 (7), 2449-2456, 2002
832002
Access to substance use treatment among young adults who use prescription opioids non-medically
EJ Liebling, JL Yedinak, TC Green, SE Hadland, MA Clark, BDL Marshall
Substance Abuse Treatment, Prevention, and Policy 11, 1-12, 2016
812016
Системата не може да изпълни операцията сега. Опитайте отново по-късно.
Статии 1–20