| Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011 | 794 | 2011 |
| Recent developments in targeting carbonic anhydrase IX for cancer therapeutics PC McDonald, JY Winum, CT Supuran, S Dedhar Oncotarget 3 (1), 84, 2012 | 456 | 2012 |
| Carbonic anhydrase IX: a new druggable target for the design of antitumor agents JY Winum, M Rami, A Scozzafava, JL Montero, C Supuran Medicinal research reviews 28 (3), 445-463, 2008 | 296 | 2008 |
| Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors N Touisni, A Maresca, PC McDonald, Y Lou, A Scozzafava, S Dedhar, ... Journal of medicinal chemistry 54 (24), 8271-8277, 2011 | 284 | 2011 |
| Sulfamates and their therapeutic potential JY Winum, A Scozzafava, JL Montero, CT Supuran Medicinal research reviews 25 (2), 186-228, 2005 | 261 | 2005 |
| Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic … A Cecchi, A Hulikova, J Pastorek, S Pastoreková, A Scozzafava, ... Journal of medicinal chemistry 48 (15), 4834-4841, 2005 | 238 | 2005 |
| Therapeutic potential of sulfamides as enzyme inhibitors JY Winum, A Scozzafava, JL Montero, CT Supuran Medicinal research reviews 26 (6), 767-792, 2006 | 226 | 2006 |
| Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1, 3, 5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II … V Garaj, L Puccetti, G Fasolis, JY Winum, JL Montero, A Scozzafava, ... Bioorganic & medicinal chemistry letters 15 (12), 3102-3108, 2005 | 188 | 2005 |
| Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts RG Gieling, M Babur, L Mamnani, N Burrows, BA Telfer, F Carta, ... Journal of medicinal chemistry 55 (11), 5591-5600, 2012 | 181 | 2012 |
| Carbonic anhydrase IX inhibitors in cancer therapy: an update CT Supuran, JY Winum Future medicinal chemistry 7 (11), 1407-1414, 2015 | 176 | 2015 |
| Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid … JY Winum, D Vullo, A Casini, JL Montero, A Scozzafava, CT Supuran Journal of Medicinal Chemistry 46 (11), 2197-2204, 2003 | 175 | 2003 |
| Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the … JY Winum, C Temperini, K El Cheikh, A Innocenti, D Vullo, S Ciattini, ... Journal of Medicinal Chemistry 49 (24), 7024-7031, 2006 | 171 | 2006 |
| Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase F Abbate, JY Winum, BVL Potter, A Casini, JL Montero, A Scozzafava, ... Bioorganic & medicinal chemistry letters 14 (1), 231-234, 2004 | 166 | 2004 |
| Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment A Angeli, F Carta, A Nocentini, JY Winum, R Zalubovskis, A Akdemir, ... Metabolites 10 (10), 412, 2020 | 147 | 2020 |
| Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1, 2, 4-triazine … V Garaj, L Puccetti, G Fasolis, JY Winum, JL Montero, A Scozzafava, ... Bioorganic & Medicinal Chemistry Letters 14 (21), 5427-5433, 2004 | 135 | 2004 |
| The importance of sulfur-containing motifs in drug design and discovery M Mustafa, JY Winum Expert opinion on drug discovery 17 (5), 501-512, 2022 | 134 | 2022 |
| Drug design of zinc-enzyme inhibitors: functional, structural, and disease applications B Wang John Wiley & Sons, 2009 | 131 | 2009 |
| Therapeutic applications of glycosidic carbonic anhydrase inhibitors JY Winum, SA Poulsen, CT Supuran Medicinal research reviews 29 (3), 419-435, 2009 | 129 | 2009 |
| Benzoxaborole compounds for therapeutic uses: a patent review (2010-2018) A Nocentini, CT Supuran, JY Winum Expert opinion on therapeutic patents 28 (6), 493-504, 2018 | 125 | 2018 |
| Carbonic anhydrase inhibitors: hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX G De Simone, RM Vitale, A Di Fiore, C Pedone, A Scozzafava, JL Montero, ... Journal of medicinal chemistry 49 (18), 5544-5551, 2006 | 124 | 2006 |
Andrea ScozzafavaProfessore di chimica, Università di FirenzeПотвърден имейл адрес: unifi.it
