Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation H Belaghzal, J Dekker, JH Gibcus Methods 123, 56-65, 2017 | 323 | 2017 |
Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics H Belaghzal, T Borrman, AD Stephens, DL Lafontaine, SV Venev, Z Weng, ... Nature genetics 53 (3), 367-378, 2021 | 100 | 2021 |
CBFβ-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia JA Pulikkan, M Hegde, HM Ahmad, H Belaghzal, A Illendula, J Yu, ... Cell 174 (1), 172-186. e21, 2018 | 95 | 2018 |
Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6 YJ Hu, H Belaghzal, WY Hsiao, J Qi, JE Bradner, DA Guertin, S Sif, ... Nucleic Acids Research 43 (16), 7790-7804, 2015 | 40 | 2015 |
Compartment-dependent chromatin interaction dynamics revealed by liquid chromatin Hi-C H Belaghzal, T Borrman, AD Stephens, DL Lafontaine, SV Venev, Z Weng, ... BioRxiv, 704957, 2019 | 27 | 2019 |
RNA-mediated symmetry breaking enables singular olfactory receptor choice AD Pourmorady, EV Bashkirova, AM Chiariello, H Belagzhal, A Kodra, ... Nature 625 (7993), 181-188, 2024 | 18 | 2024 |
Compartment-dependent chromatin interaction dynamics revealed by liquid chromatin Hi-C. bioRxiv, 704957 H Belaghzal, T Borrman, AD Stephens, DL Lafontaine, SV Venev, Z Weng, ... | 8 | 2019 |
CBFβ-SMMHC Inhibition Disrupts Enhancer Chromatin Dynamics and Represses MYC Transcriptional Program in Inv (16) Leukemia JA Pulikkan, M Hegde, H Belaghzal, A Illendula, J Yu, H Ahmed, ... Blood 130, 784, 2017 | 1 | 2017 |
1360 Controlled epigenetic upregulation of CXCL9 and CXCL10 in hepatocellular carcinoma promotes T-cell recruitment E Lee, H Belaghzal, M Pacaro, C Vergato, S Mildrum, S Siecinski, D Yarar, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
Compositions and methods for modulating myc expression AE Witt, JD Farelli, AW Scheidegger, WT Senapedis Jr, JM Kennedy, ... US Patent App. 18/257,483, 2024 | | 2024 |
Tuned Upregulation of Diverse Gene Targets Using Programmable Epigenomic Controllers J Farelli, C Morrison-Smith, M Gibson, M Gurnani, P Dhanania, ... MOLECULAR THERAPY 32 (4), 351-352, 2024 | | 2024 |
Detection and quantification of site-specific DNA methylation from liquid biopsies as a pharmacodynamic biomarker of OTX-2002, a novel MYC-targeting epigenomic mRNA therapeutic J Chen, W Senapedis, S Siecinski, E Figueroa, A Katz, S Mildrum, ... Cancer Research 84 (6), 2024 | | 2024 |
Compositions and methods for inhibiting the expression of multiple genes LM Beech, JJ Smith, R Karnik, KA Goss, AW Scheidegger, JM Kennedy, ... US Patent App. 18/028,975, 2023 | | 2023 |
Novel Epigenetic Targeting of the MYC Oncogene for the Treatment of NSCLC D Yarar, E Lee, H Belaghzal, KY Chen, C Vergato, S Siecinski, J Farelli, ... MOLECULAR THERAPY 30 (4), 519-520, 2022 | | 2022 |
Long-lived memory and dynamics of liquefied chromatin E Banigan, H Belaghzal, T Borrman, J Dekker, L Mirny Bulletin of the American Physical Society 65, 2020 | | 2020 |
Chromatin Interaction Dynamics Revealed by Liquid Chromatin Hi-C H Belaghzal University of Massachusetts Medical School, 2019 | | 2019 |
Polymer Modeling of Dynamics and Disrupted Organization of Fragmented Chromatin E Banigan, H Belaghzal, T Borrman, J Dekker, L Mirny APS March Meeting Abstracts 2018, R49. 012, 2018 | | 2018 |
HI-C 2.0: An Optimized Hi-C Procedure for High-Resolution Genome-Wide Mapping of Chromosome Conformation [preprint] H Belaghzal, J Dekker, JH Gibcus | | 2016 |
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