Следене
Houda Belaghzal
Houda Belaghzal
Associate Director at Omega Therapeutics
Потвърден имейл адрес: omegatherapeutics.com
Заглавие
Позовавания
Позовавания
Година
Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation
H Belaghzal, J Dekker, JH Gibcus
Methods 123, 56-65, 2017
3232017
Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics
H Belaghzal, T Borrman, AD Stephens, DL Lafontaine, SV Venev, Z Weng, ...
Nature genetics 53 (3), 367-378, 2021
1002021
CBFβ-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia
JA Pulikkan, M Hegde, HM Ahmad, H Belaghzal, A Illendula, J Yu, ...
Cell 174 (1), 172-186. e21, 2018
952018
Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6
YJ Hu, H Belaghzal, WY Hsiao, J Qi, JE Bradner, DA Guertin, S Sif, ...
Nucleic Acids Research 43 (16), 7790-7804, 2015
402015
Compartment-dependent chromatin interaction dynamics revealed by liquid chromatin Hi-C
H Belaghzal, T Borrman, AD Stephens, DL Lafontaine, SV Venev, Z Weng, ...
BioRxiv, 704957, 2019
272019
RNA-mediated symmetry breaking enables singular olfactory receptor choice
AD Pourmorady, EV Bashkirova, AM Chiariello, H Belagzhal, A Kodra, ...
Nature 625 (7993), 181-188, 2024
182024
Compartment-dependent chromatin interaction dynamics revealed by liquid chromatin Hi-C. bioRxiv, 704957
H Belaghzal, T Borrman, AD Stephens, DL Lafontaine, SV Venev, Z Weng, ...
82019
CBFβ-SMMHC Inhibition Disrupts Enhancer Chromatin Dynamics and Represses MYC Transcriptional Program in Inv (16) Leukemia
JA Pulikkan, M Hegde, H Belaghzal, A Illendula, J Yu, H Ahmed, ...
Blood 130, 784, 2017
12017
1360 Controlled epigenetic upregulation of CXCL9 and CXCL10 in hepatocellular carcinoma promotes T-cell recruitment
E Lee, H Belaghzal, M Pacaro, C Vergato, S Mildrum, S Siecinski, D Yarar, ...
Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024
2024
Compositions and methods for modulating myc expression
AE Witt, JD Farelli, AW Scheidegger, WT Senapedis Jr, JM Kennedy, ...
US Patent App. 18/257,483, 2024
2024
Tuned Upregulation of Diverse Gene Targets Using Programmable Epigenomic Controllers
J Farelli, C Morrison-Smith, M Gibson, M Gurnani, P Dhanania, ...
MOLECULAR THERAPY 32 (4), 351-352, 2024
2024
Detection and quantification of site-specific DNA methylation from liquid biopsies as a pharmacodynamic biomarker of OTX-2002, a novel MYC-targeting epigenomic mRNA therapeutic
J Chen, W Senapedis, S Siecinski, E Figueroa, A Katz, S Mildrum, ...
Cancer Research 84 (6), 2024
2024
Compositions and methods for inhibiting the expression of multiple genes
LM Beech, JJ Smith, R Karnik, KA Goss, AW Scheidegger, JM Kennedy, ...
US Patent App. 18/028,975, 2023
2023
Novel Epigenetic Targeting of the MYC Oncogene for the Treatment of NSCLC
D Yarar, E Lee, H Belaghzal, KY Chen, C Vergato, S Siecinski, J Farelli, ...
MOLECULAR THERAPY 30 (4), 519-520, 2022
2022
Long-lived memory and dynamics of liquefied chromatin
E Banigan, H Belaghzal, T Borrman, J Dekker, L Mirny
Bulletin of the American Physical Society 65, 2020
2020
Chromatin Interaction Dynamics Revealed by Liquid Chromatin Hi-C
H Belaghzal
University of Massachusetts Medical School, 2019
2019
Polymer Modeling of Dynamics and Disrupted Organization of Fragmented Chromatin
E Banigan, H Belaghzal, T Borrman, J Dekker, L Mirny
APS March Meeting Abstracts 2018, R49. 012, 2018
2018
HI-C 2.0: An Optimized Hi-C Procedure for High-Resolution Genome-Wide Mapping of Chromosome Conformation [preprint]
H Belaghzal, J Dekker, JH Gibcus
2016
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H Belaghzal
2016
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