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| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 1533 | 2018 |
| Mitochondria as a therapeutic target for common pathologies MP Murphy, RC Hartley Nature reviews Drug discovery 17 (12), 865-886, 2018 | 688 | 2018 |
| Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ... Nature medicine 19 (6), 753-759, 2013 | 681 | 2013 |
| Mitochondrial pharmacology RAJ Smith, RC Hartley, HM Cocheme, MP Murphy Trends in pharmacological sciences 33 (6), 341-352, 2012 | 571 | 2012 |
| Mitochondria-targeted small molecule therapeutics and probes RAJ Smith, RC Hartley, MP Murphy Antioxidants & redox signaling 15 (12), 3021-3038, 2011 | 445 | 2011 |
| Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ... Cell metabolism 13 (3), 340-350, 2011 | 336 | 2011 |
| Are carotenoids a red herring in sexual display? RC Hartley, MW Kennedy Trends in Ecology & Evolution 19 (7), 353-354, 2004 | 258 | 2004 |
| Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus IA Buskiewicz, T Montgomery, EC Yasewicz, SA Huber, MP Murphy, ... Science signaling 9 (456), ra115-ra115, 2016 | 184 | 2016 |
| Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy DB McPhail, RC Hartley, PT Gardner, GG Duthie Journal of agricultural and food chemistry 51 (6), 1684-1690, 2003 | 182 | 2003 |
| Determination of Flavonol Metabolites in Plasma and Tissues of Rats by HPLC−Radiocounting and Tandem Mass Spectrometry Following Oral Ingestion of [2-14C … W Mullen, BA Graf, ST Caldwell, RC Hartley, GG Duthie, CA Edwards, ... Journal of agricultural and food chemistry 50 (23), 6902-6909, 2002 | 160 | 2002 |
| Potential therapeutic antioxidants that combine the radical scavenging ability of myricetin and the lipophilic chain of vitamin E to effectively inhibit microsomal lipid … CJ Bennett, ST Caldwell, DB McPhail, PC Morrice, GG Duthie, RC Hartley Bioorganic & medicinal chemistry 12 (9), 2079-2098, 2004 | 156 | 2004 |
| Bioavailability of [2-14C]Quercetin-4′-glucoside in Rats W Mullen, JM Rouanet, C Auger, PL Teissèdre, ST Caldwell, RC Hartley, ... Journal of agricultural and food chemistry 56 (24), 12127-12137, 2008 | 149 | 2008 |
| Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat EL Robb, JM Gawel, D Aksentijević, HM Cochemé, TS Stewart, ... Free Radical Biology and Medicine 89, 883-894, 2015 | 147 | 2015 |
| Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ... Journal of Biological Chemistry 293 (19), 7315-7328, 2018 | 145 | 2018 |
| Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore S Chalmers, ST Caldwell, C Quin, TA Prime, AM James, AG Cairns, ... Journal of the American Chemical Society 134 (2), 758-761, 2012 | 137 | 2012 |
| Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation JL Martin, ASH Costa, AV Gruszczyk, TE Beach, FM Allen, HA Prag, ... Nature metabolism 1 (10), 966-974, 2019 | 134 | 2019 |
| Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin PJ Lim, TL Duarte, J Arezes, D Garcia-Santos, A Hamdi, SR Pasricha, ... Nature Metabolism 1 (5), 519-531, 2019 | 131 | 2019 |
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| Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo K Salin, SK Auer, AM Rudolf, GJ Anderson, AG Cairns, W Mullen, ... Biology Letters 11 (9), 20150538, 2015 | 123 | 2015 |