The positive side of the Alzheimer’s disease amyloid cross-interactions: the case of the Aβ 1-42 peptide with Tau, TTR, CysC, and ApoA1 L Ciccone, C Shi, D Di Lorenzo, AC Van Baelen, N Tonali Molecules 25 (10), 2439, 2020 | 67 | 2020 |
Carbonic anhydrase inhibitors and epilepsy: State of the art and future perspectives L Ciccone, C Cerri, S Nencetti, E Orlandini Molecules 26 (21), 6380, 2021 | 64 | 2021 |
A soluble metabolon synthesizes the isoprenoid lipid ubiquinone MH Chehade, L Pelosi, CD Fyfe, L Loiseau, B Rascalou, S Brugière, ... Cell chemical biology 26 (4), 482-492. e7, 2019 | 57 | 2019 |
Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: Analysis of structural data for future drug design L Ciccone, N Tonali, S Nencetti, E Orlandini Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1145-1162, 2020 | 49 | 2020 |
Development of thioaryl-based matrix metalloproteinase-12 inhibitors with alternative zinc-binding groups: synthesis, potentiometric, NMR, and crystallographic studies E Nuti, D Cuffaro, E Bernardini, C Camodeca, L Panelli, S Chaves, ... Journal of Medicinal Chemistry 61 (10), 4421-4435, 2018 | 48 | 2018 |
Sugar‐Based Arylsulfonamide Carboxylates as Selective and Water‐Soluble Matrix Metalloproteinase‐12 Inhibitors E Nuti, D Cuffaro, F D'Andrea, L Rosalia, L Tepshi, M Fabbi, G Carbotti, ... ChemMedChem 11 (15), 1626-1637, 2016 | 48 | 2016 |
Natural marine and terrestrial compounds as modulators of matrix metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer’s disease L Ciccone, J Vandooren, S Nencetti, E Orlandini Pharmaceuticals 14 (2), 86, 2021 | 43 | 2021 |
Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures L Ciccone, L Tepshi, S Nencetti, EA Stura New biotechnology 32 (1), 54-64, 2015 | 38 | 2015 |
Copper mediated amyloid-β binding to Transthyretin L Ciccone, C Fruchart-Gaillard, G Mourier, M Savko, S Nencetti, ... Scientific Reports 8 (1), 13744, 2018 | 35 | 2018 |
Resveratrol-like compounds as SIRT1 activators L Ciccone, E Piragine, S Brogi, C Camodeca, R Fucci, V Calderone, ... International Journal of Molecular Sciences 23 (23), 15105, 2022 | 33 | 2022 |
Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies I Polsinelli, M Savko, C Rouanet-Mehouas, L Ciccone, S Nencetti, ... Synchrotron Radiation 24 (1), 42-52, 2017 | 29 | 2017 |
Multicomponent mixtures for cryoprotection and ligand solubilization L Ciccone, L Vera, L Tepshi, L Rosalia, A Rossello, EA Stura Biotechnology Reports 7, 120-127, 2015 | 25 | 2015 |
Neuroglobin and neuroprotection: The role of natural and synthetic compounds in neuroglobin pharmacological induction L Ciccone, S Nencetti, S Socci, E Orlandini Neural regeneration research 16 (12), 2353-2358, 2021 | 23 | 2021 |
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR) L Ciccone, S Nencetti, A Rossello, EA Stura, E Orlandini Journal of Enzyme Inhibition and Medicinal Chemistry 31 (sup1), 40-51, 2016 | 21 | 2016 |
Targeting aggrecanases for Osteoarthritis Therapy: from zinc chelation to Exosite Inhibition D Cuffaro, L Ciccone, A Rossello, E Nuti, S Santamaria Journal of medicinal chemistry 65 (20), 13505-13532, 2022 | 20 | 2022 |
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide S Santamaria, D Cuffaro, E Nuti, L Ciccone, T Tuccinardi, F Liva, ... Scientific reports 11 (1), 949, 2021 | 20 | 2021 |
A new crystal form of human transthyretin obtained with a curcumin derived ligand I Polsinelli, S Nencetti, W Shepard, L Ciccone, E Orlandini, EA Stura Journal of structural biology 194 (1), 8-17, 2016 | 20 | 2016 |
Targeting different transthyretin binding sites with unusual natural compounds G Ortore, E Orlandini, A Braca, L Ciccone, A Rossello, A Martinelli, ... ChemMedChem 11 (16), 1865-1874, 2016 | 19 | 2016 |
Bifunctional inhibitors as a new tool to reduce cancer cell invasion by impairing MMP-9 homodimerization E Nuti, L Rosalia, D Cuffaro, C Camodeca, C Giacomelli, E Da Pozzo, ... ACS Medicinal Chemistry Letters 8 (3), 293-298, 2017 | 18 | 2017 |
Human TTR conformation altered by rhenium tris-carbonyl derivatives L Ciccone, C Policar, EA Stura, W Shepard Journal of structural biology 195 (3), 353-364, 2016 | 18 | 2016 |