Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia JA Pulikkan, V Dengler, PS Peramangalam, AA Peer Zada, ... Blood, The Journal of the American Society of Hematology 115 (9), 1768-1778, 2010 | 350 | 2010 |
C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations JA Pulikkan, PS Peramangalam, V Dengler, PA Ho, C Preudhomme, ... Blood, The Journal of the American Society of Hematology 116 (25), 5638-5649, 2010 | 164 | 2010 |
A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice A Illendula, JA Pulikkan, H Zong, J Grembecka, L Xue, S Sen, Y Zhou, ... Science 347 (6223), 779-784, 2015 | 132 | 2015 |
Small molecule inhibitor of CBFβ-RUNX binding for RUNX transcription factor driven cancers A Illendula, J Gilmour, J Grembecka, VSS Tirumala, A Boulton, ... EBioMedicine 8, 117-131, 2016 | 124 | 2016 |
CBFβ-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia JA Pulikkan, M Hegde, HM Ahmad, H Belaghzal, A Illendula, J Yu, ... Cell 174 (1), 172-186. e21, 2018 | 95 | 2018 |
Target proteins of C/EBPαp30 in AML: C/EBPαp30 enhances sumoylation of C/EBPαp42 via up-regulation of Ubc9 M Geletu, MY Balkhi, AA Peer Zada, M Christopeit, JA Pulikkan, ... Blood, The Journal of the American Society of Hematology 110 (9), 3301-3309, 2007 | 92 | 2007 |
C/EBPα deregulation as a paradigm for leukemogenesis JA Pulikkan, DG Tenen, G Behre Leukemia 31 (11), 2279-2285, 2017 | 78 | 2017 |
RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia AH Choi, A Illendula, JA Pulikkan, JE Roderick, J Tesell, J Yu, ... Blood, The Journal of the American Society of Hematology 130 (15), 1722-1733, 2017 | 77 | 2017 |
Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML JA Pulikkan, V Dengler, AA Peer Zada, A Kawasaki, M Geletu, Z Pasalic, ... Leukemia 24 (5), 914-923, 2010 | 77 | 2010 |
Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling JA Pulikkan, D Madera, L Xue, P Bradley, SF Landrette, YH Kuo, S Abbas, ... Blood, The Journal of the American Society of Hematology 120 (4), 868-879, 2012 | 58 | 2012 |
Proteomic discovery of Max as a novel interacting partner of C/EBPα: a Myc/Max/Mad link AA Zada, JA Pulikkan, D Bararia, M Geletu, AK Trivedi, MY Balkhi, ... Leukemia 20 (12), 2137-2146, 2006 | 42 | 2006 |
NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis L Xue, JA Pulikkan, PJM Valk, LH Castilla Blood, The Journal of the American Society of Hematology 124 (3), 426-436, 2014 | 31 | 2014 |
Proteomic analysis of acute promyelocytic leukemia: PML‐RARα leads to decreased phosphorylation of OP18 at serine 63 AAP Zada, MH Geletu, JA Pulikkan, C Müller‐Tidow, VA Reddy, ... Proteomics 6 (21), 5705-5719, 2006 | 23 | 2006 |
Emerging therapies for inv (16) AML S Surapally, DG Tenen, JA Pulikkan Blood, The Journal of the American Society of Hematology 137 (19), 2579-2584, 2021 | 19 | 2021 |
Core-binding factor leukemia hijacks the T-cell–prone PU. 1 antisense promoter E van der Kouwe, G Heller, A Czibere, JA Pulikkan, C Agreiter, ... Blood, The Journal of the American Society of Hematology 138 (15), 1345-1358, 2021 | 18 | 2021 |
Preleukemia and leukemia-initiating cell activity in inv (16) acute myeloid leukemia JA Pulikkan, LH Castilla Frontiers in oncology 8, 129, 2018 | 18 | 2018 |
DOT1L inhibitors block abnormal self-renewal induced by cohesin loss KE Heimbruch, JB Fisher, CT Stelloh, E Phillips, MH Reimer Jr, ... Scientific Reports 11 (1), 7288, 2021 | 13 | 2021 |
Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis M Guo, THM Chan, Q Zhou, O An, Y Li, Y Song, ZH Tan, VHE Ng, ... Blood, The Journal of the American Society of Hematology 141 (25), 3078-3090, 2023 | 10 | 2023 |
Selective Inhibition of the Leukemia Fusion Protein CBFβ-SMMHC By Small Molecule AI-10-49 in the Treatment of Inv(16) AML JA Pulikkan, A Illendula, J Grembecka, M Guzman, JH Bushweller, ... Blood 124 (21), 390, 2014 | 2 | 2014 |
MYCN regulates cell survival via EIF4G1 in Inv (16) acute myeloid leukemia PS Peramangalam, S Surapally, S Zheng, R Burns, N Zhu, S Rao, ... Blood 140 (Supplement 1), 9117-9118, 2022 | 1 | 2022 |