| Novel method for generating structure-based pharmacophores using energetic analysis NK Salam, R Nuti, W Sherman Journal of chemical information and modeling 49 (10), 2356-2368, 2009 | 368 | 2009 |
| Synthesis, activity, and pharmacophore development for isatin-β-thiosemicarbazones with selective activity toward multidrug-resistant cells MD Hall, NK Salam, JL Hellawell, HM Fales, CB Kensler, JA Ludwig, ... Journal of medicinal chemistry 52 (10), 3191-3204, 2009 | 215 | 2009 |
| Energetic analysis of fragment docking and application to structure-based pharmacophore hypothesis generation K Loving, NK Salam, W Sherman Journal of computer-aided molecular design 23, 541-554, 2009 | 196 | 2009 |
| Novel PPAR‐gamma agonists identified from a natural product library: A virtual screening, induced‐fit docking and biological assay study NK Salam, THW Huang, BP Kota, MS Kim, Y Li, DE Hibbs Chemical Biology & Drug Design 71 (1), 57-70, 2008 | 162 | 2008 |
| Contribution of explicit solvent effects to the binding affinity of small‐molecule inhibitors in blood coagulation factor serine proteases R Abel, NK Salam, J Shelley, R Farid, RA Friesner, W Sherman ChemMedChem 6 (6), 1049-1066, 2011 | 140 | 2011 |
| Structure-based approach to the prediction of disulfide bonds in proteins NK Salam, M Adzhigirey, W Sherman, DA Pearlman Protein Engineering, Design & Selection 27 (10), 365-374, 2014 | 113 | 2014 |
| 7-Hydroxy-benzopyran-4-one derivatives: A novel pharmacophore of peroxisome proliferator-activated receptor α and-γ (PPARα and γ) dual agonists A Matin, N Gavande, MS Kim, NX Yang, NK Salam, JR Hanrahan, ... Journal of medicinal chemistry 52 (21), 6835-6850, 2009 | 113 | 2009 |
| A novel LXR-α activator identified from the natural product Gynostemma pentaphyllum THW Huang, V Razmovski-Naumovski, NK Salam, RK Duke, CC Duke, ... Biochemical Pharmacology 70 (9), 1298-1308, 2005 | 104 | 2005 |
| Lycium barbarum (Goji Berry) extracts and its taurine component inhibit PPAR-γ-dependent gene transcription in human retinal pigment epithelial cells: Possible implications for … MK Song, NK Salam, BD Roufogalis, THW Huang Biochemical pharmacology 82 (9), 1209-1218, 2011 | 103 | 2011 |
| Novel γ-Aminobutyric Acid ρ1 Receptor Antagonists; Synthesis, Pharmacological Activity and Structure−Activity Relationships RJ Kumar, M Chebib, DE Hibbs, HL Kim, GAR Johnston, NK Salam, ... Journal of medicinal chemistry 51 (13), 3825-3840, 2008 | 46 | 2008 |
| Novel Cyclic Phosphinic Acids as GABAC ρ Receptor Antagonists: Design, Synthesis, and Pharmacology N Gavande, I Yamamoto, NK Salam, TH Ai, PM Burden, GAR Johnston, ... ACS Medicinal Chemistry Letters 2 (1), 11-16, 2011 | 37 | 2011 |
| On the value of homology models for virtual screening: discovering hCXCR3 antagonists by pharmacophore-based and structure-based approaches D Huang, Q Gu, H Ge, J Ye, NK Salam, A Hagler, H Chen, J Xu Journal of chemical information and modeling 52 (5), 1356-1366, 2012 | 34 | 2012 |
| Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site A Manos-Turvey, KM Cergol, NK Salam, EMM Bulloch, G Chi, A Pang, ... Organic & biomolecular chemistry 10 (46), 9223-9236, 2012 | 25 | 2012 |
| Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions TYE Liaw, NK Salam, MJ McKay, AM Cunningham, DE Hibbs, ... Molecular cancer therapeutics 7 (10), 3150-3159, 2008 | 23 | 2008 |
| T-cell antigen receptor-alpha chain transmembrane peptides: Correlation between structure and function M Ali, NK Salam, M Amon, V Bender, DE Hibbs, N Manolios International Journal of Peptide Research and Therapeutics 12, 261-267, 2006 | 21 | 2006 |
| High resolution crystal structures of human kynurenine aminotransferase‐I bound to PLP cofactor, and in complex with aminooxyacetate NA Nadvi, NK Salam, J Park, FN Akladios, V Kapoor, CA Collyer, ... Protein Science 26 (4), 727-736, 2017 | 16 | 2017 |
| Polyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metal ATS Lo, NK Salam, DE Hibbs, PJ Rutledge, MH Todd PLoS One 6 (5), e17446, 2011 | 13 | 2011 |
| A benchmark server using high resolution protein structure data, and benchmark results for membrane helix predictions EM Rath, D Tessier, AA Campbell, HC Lee, T Werner, NK Salam, LK Lee, ... BMC bioinformatics 14, 1-11, 2013 | 12 | 2013 |
| Generation of structure-based pharmacophores using energetic analysis–application on fragment docking K Loving, N Salam, D Cappel, W Sherman Journal of Cheminformatics 3 (Suppl 1), O20, 2011 | 2 | 2011 |
| Compounds with mdr1-inverse activity MD Hall, MM Gottesman, JL Hellawell, JA Ludwig, HM Fales, NK Salam, ... US Patent App. 12/867,206, 2010 | 2 | 2010 |