Master transcription factors and mediator establish super-enhancers at key cell identity genes WA Whyte, DA Orlando, D Hnisz, BJ Abraham, CY Lin, MH Kagey, ... Cell 153 (2), 307-319, 2013 | 4081 | 2013 |
Selective inhibition of tumor oncogenes by disruption of super-enhancers J Lovén, HA Hoke, CY Lin, A Lau, DA Orlando, CR Vakoc, JE Bradner, ... Cell 153 (2), 320-334, 2013 | 2995 | 2013 |
Transcriptional amplification in tumor cells with elevated c-Myc CY Lin, J Lovén, PB Rahl, RM Paranal, CB Burge, JE Bradner, TI Lee, ... Cell 151 (1), 56-67, 2012 | 1711 | 2012 |
c-Myc regulates transcriptional pause release PB Rahl, CY Lin, AC Seila, RA Flynn, S McCuine, CB Burge, PA Sharp, ... Cell 141 (3), 432-445, 2010 | 1478 | 2010 |
Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma B Chapuy, MR McKeown, CY Lin, S Monti, MGM Roemer, J Qi, PB Rahl, ... Cancer cell 24 (6), 777-790, 2013 | 861 | 2013 |
Revisiting global gene expression analysis J Lovén, DA Orlando, AA Sigova, CY Lin, PB Rahl, CB Burge, DL Levens, ... Cell 151 (3), 476-482, 2012 | 724 | 2012 |
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer S Shu, CY Lin, HH He, RM Witwicki, DP Tabassum, JM Roberts, ... Nature 529 (7586), 413-417, 2016 | 651 | 2016 |
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis JD Brown, CY Lin, Q Duan, G Griffin, AJ Federation, RM Paranal, S Bair, ... Molecular cell 56 (2), 219-231, 2014 | 629 | 2014 |
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells AA Sigova, AC Mullen, B Molinie, S Gupta, DA Orlando, MG Guenther, ... Proceedings of the National Academy of Sciences 110 (8), 2876-2881, 2013 | 520 | 2013 |
Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers D Hnisz, J Schuijers, CY Lin, AS Weintraub, BJ Abraham, TI Lee, ... Molecular cell 58 (2), 362-370, 2015 | 512 | 2015 |
DHODH modulates transcriptional elongation in the neural crest and melanoma RM White, J Cech, S Ratanasirintrawoot, CY Lin, PB Rahl, CJ Burke, ... Nature 471 (7339), 518-522, 2011 | 499 | 2011 |
BET bromodomains mediate transcriptional pause release in heart failure P Anand, JD Brown, CY Lin, J Qi, R Zhang, PC Artero, MA Alaiti, J Bullard, ... Cell 154 (3), 569-582, 2013 | 443 | 2013 |
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ... Molecular cell 67 (1), 5-18. e19, 2017 | 439 | 2017 |
Active medulloblastoma enhancers reveal subgroup-specific cellular origins CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ... Nature 530 (7588), 57-62, 2016 | 425 | 2016 |
In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice LW Koblan, MR Erdos, C Wilson, WA Cabral, JM Levy, ZM Xiong, ... Nature 589 (7843), 608-614, 2021 | 406 | 2021 |
Global control of cell-cycle transcription by coupled CDK and network oscillators DA Orlando, CY Lin, A Bernard, JY Wang, JES Socolar, ES Iversen, ... Nature 453 (7197), 944-947, 2008 | 396 | 2008 |
SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase X Ji, Y Zhou, S Pandit, J Huang, H Li, CY Lin, R Xiao, CB Burge, XD Fu Cell 153 (4), 855-868, 2013 | 370 | 2013 |
Memory-based model editing at scale E Mitchell, C Lin, A Bosselut, CD Manning, C Finn International Conference on Machine Learning, 15817-15831, 2022 | 322 | 2022 |
Models of human core transcriptional regulatory circuitries V Saint-André, AJ Federation, CY Lin, BJ Abraham, J Reddy, TI Lee, ... Genome research 26 (3), 385-396, 2016 | 299 | 2016 |
Mutant NPM1 maintains the leukemic state through HOX expression L Brunetti, MC Gundry, D Sorcini, AG Guzman, YH Huang, ... Cancer cell 34 (3), 499-512. e9, 2018 | 287 | 2018 |