Статии с изисквания за обществен достъп - Philip CohenНаучете повече
Не е налице никъде: 2
Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors
R Akué-Gédu, E Rossignol, S Azzaro, S Knapp, P Filippakopoulos, ...
Journal of medicinal chemistry 52 (20), 6369-6381, 2009
Изисквания: Canadian Institutes of Health Research, Genome Canada
Bill Whelan's impact on my life and career
P Cohen
Molecular Aspects of Medicine 46, 11-13, 2015
Изисквания: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
Налице някъде: 65
The ground state of embryonic stem cell self-renewal
QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ...
nature 453 (7194), 519-523, 2008
Изисквания: Canadian Institutes of Health Research
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
Изисквания: US National Institutes of Health, Cancer Research UK, UK Medical Research …
Kinase drug discovery 20 years after imatinib: progress and future directions
P Cohen, D Cross, PA Jänne
Nature reviews drug discovery 20 (7), 551-569, 2021
Изисквания: UK Medical Research Council, Wellcome Trust
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
CH Emmerich, A Ordureau, S Strickson, JSC Arthur, PGA Pedrioli, ...
Proceedings of the National Academy of Sciences 110 (38), 15247-15252, 2013
Изисквания: UK Medical Research Council, Wellcome Trust
IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation
KM Lin, W Hu, TD Troutman, M Jennings, T Brewer, X Li, S Nanda, ...
Proceedings of the National Academy of Sciences 111 (2), 775-780, 2014
Изисквания: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
The IkappaB kinase family phosphorylates the Parkinson’s disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling
N Dzamko, F Inesta-Vaquera, J Zhang, C Xie, H Cai, S Arthur, L Tan, ...
PloS one 7 (6), e39132, 2012
Изисквания: US National Institutes of Health
The TLR and IL-1 signalling network at a glance
P Cohen
Journal of cell science 127 (11), 2383-2390, 2014
Изисквания: UK Medical Research Council, Wellcome Trust
The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
S Strickson, DG Campbell, CH Emmerich, A Knebel, L Plater, MS Ritorto, ...
Biochemical Journal 451 (3), 427-437, 2013
Изисквания: UK Medical Research Council, Wellcome Trust
Polyubiquitin binding to ABIN1 is required to prevent autoimmunity
SK Nanda, RKC Venigalla, A Ordureau, JC Patterson-Kane, DW Powell, ...
Journal of Experimental Medicine 208 (6), 1215-1228, 2011
Изисквания: US National Institutes of Health
TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages
S Rousseau, M Papoutsopoulou, A Symons, D Cook, JM Lucocq, ...
Journal of cell science 121 (2), 149-154, 2008
Изисквания: Versus Arthritis, UK
Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting
CH Emmerich, P Cohen
Biochemical and biophysical research communications 466 (1), 1-14, 2015
Изисквания: UK Medical Research Council, Wellcome Trust
Molecular control of the NEMO family of ubiquitin-binding proteins
K Clark, S Nanda, P Cohen
Nature reviews Molecular cell biology 14 (10), 673-685, 2013
Изисквания: UK Medical Research Council, Wellcome Trust
The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells
IR Kelsall, J Zhang, A Knebel, JSC Arthur, P Cohen
Proceedings of the National Academy of Sciences 116 (27), 13293-13298, 2019
Изисквания: UK Medical Research Council, Wellcome Trust
An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation
J Zhang, K Clark, T Lawrence, MW Peggie, P Cohen
Biochemical Journal 461 (3), 531-537, 2014
Изисквания: Versus Arthritis, UK, UK Medical Research Council, Wellcome Trust
The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways
P Cohen, S Strickson
Cell Death & Differentiation 24 (7), 1153-1159, 2017
Изисквания: UK Medical Research Council, Wellcome Trust
HCK is a survival determinant transactivated by mutated MYD88, and a direct target of ibrutinib
G Yang, SJ Buhrlage, L Tan, X Liu, J Chen, L Xu, N Tsakmaklis, JG Chen, ...
Blood, The Journal of the American Society of Hematology 127 (25), 3237-3252, 2016
Изисквания: UK Medical Research Council
Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells
M Lopez-Pelaez, DJ Lamont, M Peggie, N Shpiro, NS Gray, P Cohen
Proceedings of the National Academy of Sciences 111 (49), 17432-17437, 2014
Изисквания: UK Medical Research Council, Wellcome Trust
Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice
E Pauls, SK Nanda, H Smith, R Toth, JSC Arthur, P Cohen
The Journal of Immunology 191 (5), 2717-2730, 2013
Изисквания: UK Medical Research Council, Wellcome Trust
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