mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases M Palmieri, R Pal, HR Nelvagal, P Lotfi, GR Stinnett, ML Seymour, ... Nature communications 8 (1), 14338, 2017 | 455 | 2017 |
CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis A di Ronza, L Bajaj, J Sharma, D Sanagasetti, P Lotfi, CJ Adamski, ... Nature cell biology 20 (12), 1370-1377, 2018 | 107 | 2018 |
MiR‐590 promotes transdifferentiation of porcine and human fibroblasts toward a cardiomyocyte‐like fate by directly repressing specificity protein 1 VP Singh, M Mathison, V Patel, D Sanagasetti, BW Gibson, J Yang, ... Journal of the American Heart Association 5 (11), e003922, 2016 | 59 | 2016 |
In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration M Mathison, VP Singh, MJ Chiuchiolo, D Sanagasetti, Y Mao, VB Patel, ... The Journal of thoracic and cardiovascular surgery 153 (2), 329-339. e3, 2017 | 49 | 2017 |
Enhanced generation of induced cardiomyocytes using a small‐molecule cocktail to overcome barriers to cardiac cellular reprogramming VP Singh, JP Pinnamaneni, A Pugazenthi, D Sanagasetti, M Mathison, ... Journal of the American Heart Association 9 (12), e015686, 2020 | 35 | 2020 |
The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis L Yang, L Liu, H Gao, JP Pinnamaneni, D Sanagasetti, VP Singh, K Wang, ... Journal of Hematology & Oncology 10, 1-15, 2017 | 35 | 2017 |
Cardiac reprogramming factor Gata4 reduces postinfarct cardiac fibrosis through direct repression of the profibrotic mediator snail M Mathison, VP Singh, D Sanagasetti, L Yang, JP Pinnamaneni, J Yang, ... The Journal of thoracic and cardiovascular surgery 154 (5), 1601-1610. e3, 2017 | 32 | 2017 |
Hippo pathway effector Tead1 induces cardiac fibroblast to cardiomyocyte reprogramming VP Singh, JP Pinnamaneni, A Pugazenthi, D Sanagasetti, M Mathison, ... Journal of the American Heart Association 10 (24), e022659, 2021 | 28 | 2021 |
Correction: Corrigendum: mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases M Palmieri, R Pal, HR Nelvagal, P Lotfi, GR Stinnett, ML Seymour, ... Nature communications 8 (1), 15793, 2017 | 20 | 2017 |
p63 Silencing induces reprogramming of cardiac fibroblasts into cardiomyocyte-like cells V Patel, VP Singh, JP Pinnamaneni, D Sanagasetti, J Olive, M Mathison, ... The Journal of thoracic and cardiovascular surgery 156 (2), 556-565. e1, 2018 | 18 | 2018 |
Fibroblast transition to an endothelial “trans” state improves cell reprogramming efficiency M Mathison, D Sanagasetti, VP Singh, A Pugazenthi, JP Pinnamaneni, ... Scientific Reports 11 (1), 22605, 2021 | 12 | 2021 |
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases. Nat Commun. 2017; 8: 14338 M Palmieri, R Pal, HR Nelvagal, P Lotfi, GR Stinnett, ML Seymour, ... | 12 | |
p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation JP Pinnamaneni, VP Singh, MB Kim, CT Ryan, A Pugazenthi, ... Scientific Reports 12 (1), 11416, 2022 | 10 | 2022 |
Sall4 blocks cardiac trans-differentiation but stimulates cardiac stem-like cell (iPSC) generation and improve post MI function in vivo L Yang, P Pinnamaneni, H Gao, D Sanagasetti, V Singh, M Mathison, ... Circulation Research 123 (Suppl_1), A349-A349, 2018 | 2 | 2018 |
Hippo Pathway Effector TEAD1 Promotes Direct Cardiac Reprogramming VP Singh, JP Pinnamaneni, A Pugazenthi, D Sanagasetti, A Almousa, ... Circulation 140 (Suppl_1), A15790-A15790, 2019 | 1 | 2019 |
Unlocking reprogramming capability: silencing antiplasticity gene p63 enhances the reprogramming of fibroblasts into induced cardiomyocytes V Patel, A Cooney, E Flores, V Singh, M Mathison, D Sanagasetti, ... Circulation Research 119 (suppl_1), A33-A33, 2016 | 1 | 2016 |
Direct reprogramming of cardiac fibroblasts into cardiomyocytes using an endothelial cell transdifferentiation strategy M Mathison, T Rosengart, VP Singh, D Sanagasetti, JP Pinnamaneni, ... US Patent App. 17/593,286, 2022 | | 2022 |
Fibroblast Transition to an Endothelial “Trans” State Improves Cell Reprogramming Efficiency and Post-Infarct Cardiac Function M Mathison, D Sanagasetti, VP Singh, A Jang, A Pugazenthi, ... Circulation 140 (Suppl_1), A16054-A16054, 2019 | | 2019 |
Downregulation of Gene p63 Enhances Reprogramming of Human Cardiac Fibroblasts Towards a Cardiac Fate JP Pinnamaneni, VP Singh, M Kim, A Almousa, D Sanagasetti, ... Circulation 140 (Suppl_1), A14878-A14878, 2019 | | 2019 |
Gata4, Mef2c and Tbx5 More Efficiently Transdifferentiate Endothelial Cells into Cardiomyocyte-like Cells Through Endothelial-Mesenchymal Transition Process D Sanagasetti, VP Singh, JP Pinnamaneni, A Pugazenthi, A Jang, D So, ... Circulation Research 123 (Suppl_1), A470-A470, 2018 | | 2018 |