| The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods B Zdrazil, E Felix, F Hunter, EJ Manners, J Blackshaw, S Corbett, ... Nucleic acids research 52 (D1), D1180-D1192, 2024 | 387 | 2024 |
| Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 366 | 2017 |
| The N terminus of monoamine transporters is a lever required for the action of amphetamines S Sucic, S Dallinger, B Zdrazil, R Weissensteiner, TN Jørgensen, M Holy, ... Journal of Biological Chemistry 285 (14), 10924-10938, 2010 | 155 | 2010 |
| Artificial intelligence for natural product drug discovery MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ... Nature Reviews Drug Discovery 22 (11), 895-916, 2023 | 152 | 2023 |
| Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project SE Escher, H Kamp, SH Bennekou, A Bitsch, C Fisher, R Graepel, ... Archives of toxicology 93, 3643-3667, 2019 | 141 | 2019 |
| Scientific competency questions as the basis for semantically enriched open pharmacological space development K Azzaoui, E Jacoby, S Senger, EC Rodríguez, M Loza, B Zdrazil, M Pinto, ... Drug Discovery Today 18 (17-18), 843-852, 2013 | 71 | 2013 |
| The rise and fall of a scaffold: a trend analysis of scaffolds in the medicinal chemistry literature B Zdrazil, R Guha Journal of Medicinal Chemistry 61 (11), 4688-4703, 2017 | 56 | 2017 |
| EMBL’s European bioinformatics Institute (EMBL-EBI) in 2022 M Thakur, A Bateman, C Brooksbank, M Freeberg, M Harrison, M Hartley, ... Nucleic acids research 51 (D1), D9-D17, 2023 | 50 | 2023 |
| Moving targets in drug discovery B Zdrazil, L Richter, N Brown, R Guha Scientific reports 10 (1), 20213, 2020 | 42 | 2020 |
| The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research J Ratnam, B Zdrazil, D Digles, E Cuadrado-Rodriguez, JM Neefs, ... PLoS One 9 (12), e115460, 2014 | 41 | 2014 |
| Selectivity profiling of BCRP versus P-gp inhibition: from automated collection of polypharmacology data to multi-label learning F Montanari, B Zdrazil, D Digles, GF Ecker Journal of cheminformatics 8, 1-13, 2016 | 40 | 2016 |
| Differences in metformin and thiamine uptake between human and mouse organic cation transporter 1: structural determinants and potential consequences for intrahepatic … MJ Meyer, A Tuerkova, S Römer, C Wenzel, T Seitz, J Gaedcke, S Oswald, ... Drug Metabolism and Disposition 48 (12), 1380-1392, 2020 | 36 | 2020 |
| Annotating human P‐glycoprotein bioassay data B Zdrazil, M Pinto, P Vasanthanathan, AJ Williams, LZ Balderud, ... Molecular Informatics 31 (8), 599-609, 2012 | 35 | 2012 |
| A binding mode hypothesis of tiagabine confirms liothyronine effect on γ-aminobutyric acid transporter 1 (GAT1) A Jurik, B Zdrazil, M Holy, T Stockner, HH Sitte, GF Ecker Journal of medicinal chemistry 58 (5), 2149-2158, 2015 | 34 | 2015 |
| Opioids as substrates and inhibitors of the genetically highly variable organic cation transporter OCT1 MJ Meyer, VE Neumann, HR Friesacher, B Zdrazil, J Brockmöller, ... Journal of medicinal chemistry 62 (21), 9890-9905, 2019 | 30 | 2019 |
| Identification of anticancer OATP2B1 substrates by an in vitro triple-fluorescence-based cytotoxicity screen T Windt, S Tóth, I Patik, J Sessler, N Kucsma, Á Szepesi, B Zdrazil, ... Archives of toxicology 93 (4), 953-964, 2019 | 28 | 2019 |
| Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action SE Escher, A Aguayo-Orozco, E Benfenati, A Bitsch, T Braunbeck, ... Toxicology in vitro 79, 105269, 2022 | 27 | 2022 |
| Current advances in studying clinically relevant transporters of the solute carrier (SLC) family by connecting computational modeling and data science A Türková, B Zdrazil Computational and Structural Biotechnology Journal 17, 390-405, 2019 | 26 | 2019 |
| Exploiting open data: a new era in pharmacoinformatics D Goldmann, F Montanari, L Richter, B Zdrazil, GF Ecker Future medicinal chemistry 6 (5), 503-514, 2014 | 24 | 2014 |
| Identifying novel inhibitors for hepatic organic anion transporting polypeptides by machine learning-based virtual screening A Tuerkova, BJ Bongers, U Norinder, O Ungvári, V Székely, A Tarnovskiy, ... Journal of Chemical Information and Modeling 62 (24), 6323-6335, 2022 | 23 | 2022 |
Gerhard F EckerProfessor of Pharmacoinformatics, University of ViennaПотвърден имейл адрес: univie.ac.at