| CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells SJ Liu, MA Horlbeck, SW Cho, HS Birk, M Malatesta, D He, FJ Attenello, ... Science 355 (6320), eaah7111, 2017 | 786 | 2017 |
| Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system MJ Workman, MM Mahe, S Trisno, HM Poling, CL Watson, N Sundaram, ... Nature medicine 23 (1), 49-59, 2017 | 645 | 2017 |
| CRISPR interference efficiently induces specific and reversible gene silencing in human iPSCs MA Mandegar, N Huebsch, EB Frolov, E Shin, A Truong, MP Olvera, ... Cell stem cell 18 (4), 541-553, 2016 | 577 | 2016 |
| Human iPSC-based cardiac microphysiological system for drug screening applications A Mathur, P Loskill, K Shao, N Huebsch, SG Hong, SG Marcus, N Marks, ... Scientific reports 5 (1), 8883, 2015 | 573 | 2015 |
| Automated video-based analysis of contractility and calcium flux in human-induced pluripotent stem cell-derived cardiomyocytes cultured over different spatial scales N Huebsch, P Loskill, MA Mandegar, NC Marks, AS Sheehan, Z Ma, ... Tissue Engineering Part C: Methods 21 (5), 467-479, 2015 | 325 | 2015 |
| Miniaturized iPS-cell-derived cardiac muscles for physiologically relevant drug response analyses N Huebsch, P Loskill, N Deveshwar, CI Spencer, LM Judge, ... Scientific reports 6 (1), 24726, 2016 | 254 | 2016 |
| Esophageal organoids from human pluripotent stem cells delineate Sox2 functions during esophageal specification SL Trisno, KED Philo, KW McCracken, EM Catá, S Ruiz-Torres, ... Cell stem cell 23 (4), 501-515. e7, 2018 | 163 | 2018 |
| A non-invasive platform for functional characterization of stem-cell-derived cardiomyocytes with applications in cardiotoxicity testing M Maddah, JD Heidmann, MA Mandegar, CD Walker, S Bolouki, ... Stem cell reports 4 (4), 621-631, 2015 | 161 | 2015 |
| Multi-imaging method to assay the contractile mechanical output of micropatterned human iPSC-derived cardiac myocytes AJS Ribeiro, O Schwab, MA Mandegar, YS Ang, BR Conklin, D Srivastava, ... Circulation research 120 (10), 1572-1583, 2017 | 124 | 2017 |
| Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload Z Ma, N Huebsch, S Koo, MA Mandegar, B Siemons, S Boggess, ... Nature biomedical engineering 2 (12), 955-967, 2018 | 113 | 2018 |
| Haploids adapt faster than diploids across a range of environments AC Gerstein, LA Cleathero, MA Mandegar, SP Otto Journal of evolutionary biology 24 (3), 531-540, 2011 | 102 | 2011 |
| A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress LM Judge, JA Perez-Bermejo, A Truong, AJS Ribeiro, JC Yoo, CL Jensen, ... JCI insight 2 (14), e94623, 2017 | 94 | 2017 |
| Mitotic recombination counteracts the benefits of genetic segregation MA Mandegar, SP Otto Proceedings of the Royal Society B: Biological Sciences 274 (1615), 1301-1307, 2007 | 94 | 2007 |
| An improved technique for chromosomal analysis of human ES and iPS cells D Moralli, M Yusuf, MA Mandegar, S Khoja, ZL Monaco, EV Volpi Stem Cell Reviews and Reports 7, 471-477, 2011 | 63 | 2011 |
| Deep profiling reveals substantial heterogeneity of integration outcomes in CRISPR knock-in experiments H Canaj, JA Hussmann, H Li, KA Beckman, L Goodrich, NH Cho, YJ Li, ... BioRxiv, 841098, 2019 | 55 | 2019 |
| A model of the evolution of dichogamy incorporating sex‐ratio selection, anther‐stigma interference, and inbreeding depression RD Sargent, MA Mandegar, SP Otto Evolution 60 (5), 934-944, 2006 | 49 | 2006 |
| Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes Francis Grafton, Jaclyn Ho, Sara Ranjbarvaziri, Farshad Farshidfar ... eLife, 2021 | 46 | 2021 |
| Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy J Yang, F Grafton, S Ranjbarvaziri, A Budan, F Farshidfar, M Cho, E Xu, ... Science translational medicine 14 (652), eabl5654, 2022 | 36 | 2022 |
| Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference ARG Libby, DA Joy, PL So, MA Mandegar, JM Muncie, ... Elife 7, e36045, 2018 | 36 | 2018 |
| Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells MA Mandegar, D Moralli, S Khoja, S Cowley, DYL Chan, M Yusuf, ... Human molecular genetics 20 (15), 2905-2913, 2011 | 29 | 2011 |