| SAAM II: simulation, analysis, and modeling software for tracer and pharmacokinetic studies PHR Barrett, BM Bell, C Cobelli, H Golde, A Schumitzky, P Vicini, ... Metabolism 47 (4), 484-492, 1998 | 527 | 1998 |
| Quantitative magnetic resonance imaging analysis of neovasculature volume in carotid atherosclerotic plaque W Kerwin, A Hooker, M Spilker, P Vicini, M Ferguson, T Hatsukami, ... Circulation 107 (6), 851-856, 2003 | 525 | 2003 |
| alpha-Lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes. T Konrad, P Vicini, K Kusterer, A Höflich, A Assadkhani, HJ Böhles, ... Diabetes care 22 (2), 280-287, 1999 | 333 | 1999 |
| Quantitative and systems pharmacology in the post-genomic era: new approaches to discovering drugs and understanding therapeutic mechanisms PK Sorger, SRB Allerheiligen, DR Abernethy, RB Altman, KLR Brouwer, ... An NIH white paper by the QSP workshop group 48, 1-47, 2011 | 332 | 2011 |
| Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice MF Hebert, X Ma, SB Naraharisetti, KM Krudys, JG Umans, GDV Hankins, ... Clinical Pharmacology & Therapeutics 85 (6), 607-614, 2009 | 277 | 2009 |
| Why has model‐informed precision dosing not yet become common clinical reality? Lessons from the past and a roadmap for the future AS Darwich, K Ogungbenro, AA Vinks, JR Powell, JL Reny, N Marsousi, ... Clinical Pharmacology & Therapeutics 101 (5), 646-656, 2017 | 238 | 2017 |
| Catch-bond model derived from allostery explains force-activated bacterial adhesion W Thomas, M Forero, O Yakovenko, L Nilsson, P Vicini, E Sokurenko, ... Biophysical journal 90 (3), 753-764, 2006 | 237 | 2006 |
| The hot IVGTT two-compartment minimal model: indexes of glucose effectiveness and insulin sensitivity P Vicini, A Caumo, C Cobelli American Journal of Physiology-Endocrinology And Metabolism 273 (5), E1024-E1032, 1997 | 191 | 1997 |
| Pubertal adolescent male-female differences in insulin sensitivity and glucose effectiveness determined by the one compartment minimal model RP Hoffman, P Vicini, WI Sivitz, C Cobelli Pediatric research 48 (3), 384-388, 2000 | 171 | 2000 |
| POPED, a software for optimal experiment design in population kinetics M Foracchia, A Hooker, P Vicini, A Ruggeri Computer methods and programs in biomedicine 74 (1), 29-46, 2004 | 163 | 2004 |
| A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition C Gong, O Milberg, B Wang, P Vicini, R Narwal, L Roskos, AS Popel Journal of the Royal Society Interface 14 (134), 20170320, 2017 | 160 | 2017 |
| Amoxicillin pharmacokinetics in pregnant women: modeling and simulations of dosage strategies MA Andrew, TR Easterling, DB Carr, D Shen, ML Buchanan, T Rutherford, ... Clinical Pharmacology & Therapeutics 81 (4), 547-556, 2007 | 148 | 2007 |
| Population pharmacokinetics of durvalumab in cancer patients and association with longitudinal biomarkers of disease status PG Baverel, VFS Dubois, CY Jin, Y Zheng, X Song, X Jin, ... Clinical Pharmacology & Therapeutics 103 (4), 631-642, 2018 | 144 | 2018 |
| Evaluation of factors controlling glucose tolerance in patients with HCV infection before and after 4 months therapy with interferon‐α Konrad, Zeuzem, Vicini, Toffolo, Briem, Lormann, Herrmann, Kusterer, ... European journal of clinical investigation 30 (2), 111-121, 2000 | 132 | 2000 |
| Forearm nitric oxide balance, vascular relaxation, and glucose metabolism in NIDDM patients A Avogaro, F Piarulli, A Valerio, M Miola, M Calveri, P Pavan, P Vicini, ... Diabetes 46 (6), 1040-1047, 1997 | 131 | 1997 |
| Systems pharmacology for drug discovery and development: paradigm shift or flash in the pan? P Vicini, PH Van Der Graaf Clinical Pharmacology & Therapeutics 93 (5), 379-381, 2013 | 122 | 2013 |
| Undermodeling affects minimal model indexes: insights from a two-compartment model A Caumo, P Vicini, JJ Zachwieja, A Avogaro, K Yarasheski, DM Bier, ... American Journal of Physiology-Endocrinology And Metabolism 276 (6), E1171-E1193, 1999 | 121 | 1999 |
| Serum and lower respiratory tract drug concentrations after tobramycin inhalation in young children with cystic fibrosis M Rosenfeld, R Gibson, S McNamara, J Emerson, KS McCoy, R Shell, ... The Journal of pediatrics 139 (4), 572-577, 2001 | 98 | 2001 |
| Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through … S Planken, DC Behenna, SK Nair, TO Johnson, A Nagata, C Almaden, ... Journal of Medicinal Chemistry 60 (7), 3002-3019, 2017 | 97 | 2017 |
| Obstetric-Fetal Pharmacology Research Unit Network. Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice MF Hebert, X Ma, SB Naraharisetti, KM Krudys, JG Umans, GD Hankins, ... Clin Pharmacol Ther 85 (6), 607-614, 2009 | 93 | 2009 |