| Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach AK Krug, R Kolde, JA Gaspar, E Rempel, NV Balmer, K Meganathan, ... Archives of toxicology 87, 123-143, 2013 | 254 | 2013 |
| ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-κB to regulate the inducible nitric-oxide synthase gene S Rudders, J Gaspar, R Madore, C Voland, F Grall, A Patel, A Pellacani, ... Journal of Biological Chemistry 276 (5), 3302-3309, 2001 | 119 | 2001 |
| Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety … U Chaudhari, H Nemade, V Wagh, JA Gaspar, JK Ellis, SP Srinivasan, ... Archives of toxicology 90, 2763-2777, 2016 | 118 | 2016 |
| Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells T Waldmann, E Rempel, NV Balmer, A König, R Kolde, JA Gaspar, ... Chemical research in toxicology 27 (3), 408-420, 2014 | 114 | 2014 |
| MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes U Chaudhari, H Nemade, JA Gaspar, J Hescheler, JG Hengstler, ... Archives of toxicology 90, 3087-3098, 2016 | 105 | 2016 |
| A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors E Rempel, L Hoelting, T Waldmann, NV Balmer, S Schildknecht, ... Archives of toxicology 89, 1599-1618, 2015 | 103 | 2015 |
| Unique metabolic features of stem cells, cardiomyocytes, and their progenitors JA Gaspar, MX Doss, JG Hengstler, C Cadenas, J Hescheler, ... Circulation research 114 (8), 1346-1360, 2014 | 102 | 2014 |
| Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells K Meganathan, S Jagtap, V Wagh, J Winkler, JA Gaspar, D Hildebrand, ... Public Library of Science 7 (8), e44228, 2012 | 101 | 2012 |
| ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation C Brown, J Gaspar, A Pettit, R Lee, X Gu, H Wang, C Manning, C Voland, ... Journal of Biological Chemistry 279 (13), 12794-12803, 2004 | 75 | 2004 |
| Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic acid exposure S Colleoni, C Galli, JA Gaspar, K Meganathan, S Jagtap, J Hescheler, ... Toxicological sciences 124 (2), 370-377, 2011 | 73 | 2011 |
| Elf-1 is a transcriptional regulator of the Tie2 gene during vascular development A Dube, S Thai, J Gaspar, S Rudders, TA Libermann, L Iruela-Arispe, ... Circulation research 88 (2), 237-244, 2001 | 71 | 2001 |
| Mesoderm-derived stem cells: the link between the transcriptome and their differentiation potential J De Kock, M Najar, J Bolleyn, F Al Battah, RM Rodrigues, K Buyl, ... Stem cells and development 21 (18), 3309-3323, 2012 | 64 | 2012 |
| Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox ukn and STOP-Tox ukk tests V Shinde, L Hoelting, SP Srinivasan, J Meisig, K Meganathan, S Jagtap, ... Archives of toxicology 91, 839-864, 2017 | 63 | 2017 |
| Effects of cryopreservation on the transcriptome of human embryonic stem cells after thawing and culturing V Wagh, K Meganathan, S Jagtap, JA Gaspar, J Winkler, D Spitkovsky, ... Stem Cell Reviews and Reports 7, 506-517, 2011 | 59 | 2011 |
| Cytosine arabinoside induces ectoderm and inhibits mesoderm expression in human embryonic stem cells during multilineage differentiation S Jagtap, K Meganathan, J Gaspar, V Wagh, J Winkler, J Hescheler, ... British journal of pharmacology 162 (8), 1743-1756, 2011 | 51 | 2011 |
| Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ P Khatri, K Obernier, IK Simeonova, A Hellwig, G Hölzl-Wenig, C Mandl, ... Scientific reports 4 (1), 3803, 2014 | 50 | 2014 |
| Ascorbic acid-induced cardiac differentiation of murine pluripotent stem cells: transcriptional profiling and effect of a small molecule synergist of Wnt/β-catenin signaling … D Ivanyuk, G Budash, Y Zheng, JA Gaspar, U Chaudhari, A Fatima, ... Cellular Physiology and Biochemistry 36 (2), 810-830, 2015 | 45 | 2015 |
| Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: effects of CREB pathway inhibition F Pistollato, J Louisse, B Scelfo, M Mennecozzi, B Accordi, G Basso, ... Toxicology and applied pharmacology 280 (2), 378-388, 2014 | 42 | 2014 |
| Extensive transcriptional regulation of chromatin modifiers during human neurodevelopment MK Weng, B Zimmer, D Pöltl, MP Broeg, V Ivanova, JA Gaspar, ... PLoS One 7 (5), e36708, 2012 | 35 | 2012 |
| Neuronal-Specific Deficiency of the Splicing Factor Tra2b Causes Apoptosis in Neurogenic Areas of the Developing Mouse Brain M Storbeck, K Hupperich, JA Gaspar, K Meganathan, L Martínez Carrera, ... PLoS One 9 (2), e89020, 2014 | 33 | 2014 |