Allosteric modulation of GPCRs: new insights and potential utility for treatment of schizophrenia and other CNS disorders DJ Foster, PJ Conn Neuron 94 (3), 431-446, 2017 | 260 | 2017 |
Antipsychotic-like effects of M4 positive allosteric modulators are mediated by CB2 receptor-dependent inhibition of dopamine release DJ Foster, JM Wilson, DH Remke, MS Mahmood, MJ Uddin, J Wess, ... Neuron 91 (6), 1244-1252, 2016 | 151 | 2016 |
Biased mGlu5-positive allosteric modulators provide in vivo efficacy without potentiating mGlu5 modulation of NMDAR currents JM Rook, Z Xiang, X Lv, A Ghoshal, JW Dickerson, TM Bridges, ... Neuron 86 (4), 1029-1040, 2015 | 143 | 2015 |
Activation of M₁ and M₄ muscarinic receptors as potential treatments for Alzheimer's disease and schizophrenia. DJ Foster, DL Choi, PJ Conn, JM Rook Neuropsychiatric disease and treatment, 2014 | 119 | 2014 |
M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location DJ Foster, PR Gentry, JE Lizardi-Ortiz, TM Bridges, MR Wood, ... Journal of Neuroscience 34 (9), 3253-3262, 2014 | 92 | 2014 |
Targeting muscarinic receptors to treat schizophrenia DJ Foster, ZK Bryant, PJ Conn Behavioural brain research 405, 113201, 2021 | 73 | 2021 |
Roles of methanogens on volatile organic sulfur compound production in anaerobically digested wastewater biosolids Y Chen, MJ Higgins, NA Maas, SN Murthy, WE Toffey, DJ Foster Water Science and Technology 52 (1-2), 67-72, 2005 | 65 | 2005 |
Emerging approaches for treatment of schizophrenia: modulation of cholinergic signaling DJ Foster, CK Jones, PJ Conn Discovery medicine 14 (79), 413, 2012 | 57 | 2012 |
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice T Pancani, DJ Foster, MS Moehle, TJ Bichell, E Bradley, TM Bridges, ... Proceedings of the National Academy of Sciences 112 (45), 14078-14083, 2015 | 50 | 2015 |
Receptor regulation of osmolyte homeostasis in neural cells SK Fisher, AM Heacock, RF Keep, DJ Foster The Journal of physiology 588 (18), 3355-3364, 2010 | 49 | 2010 |
Volume‐dependent osmolyte efflux from neural tissues: regulation by G‐protein‐coupled receptors SK Fisher, TA Cheema, DJ Foster, AM Heacock Journal of neurochemistry 106 (5), 1998-2014, 2008 | 46 | 2008 |
Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulators SE Yohn, DJ Foster, DP Covey, MS Moehle, J Galbraith, ... Molecular Psychiatry 25 (11), 2786-2799, 2020 | 41 | 2020 |
Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward IA Reddy, NK Smith, K Erreger, D Ghose, C Saunders, DJ Foster, ... PLoS Biology 16 (7), e2006682, 2018 | 36 | 2018 |
Discovery of the First Selective M4 Muscarinic Acetylcholine Receptor Antagonists with in Vivo Antiparkinsonian and Antidystonic Efficacy MS Moehle, AM Bender, JW Dickerson, DJ Foster, A Qi, HP Cho, ... ACS Pharmacology & Translational Science 4 (4), 1306-1321, 2021 | 24 | 2021 |
Examining the role of muscarinic M5 receptors in VTA cholinergic modulation of depressive-like and anxiety-related behaviors in rats EJ Nunes, LE Rupprecht, DJ Foster, CW Lindsley, PJ Conn, NA Addy Neuropharmacology 171, 108089, 2020 | 21 | 2020 |
Co-activation of metabotropic glutamate receptor 3 and beta-adrenergic receptors modulates cyclic-AMP and long-term potentiation, and disrupts memory reconsolidation AG Walker, DJ Sheffler, AS Lewis, JW Dickerson, DJ Foster, RK Senter, ... Neuropsychopharmacology 42 (13), 2553-2566, 2017 | 17 | 2017 |
Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the … AT Garrison, DL Orsi, RA Capstick, D Whomble, J Li, TR Carter, AS Felts, ... Journal of Medicinal Chemistry 65 (8), 6273-6286, 2022 | 14 | 2022 |
Muscarinic receptor regulation of osmosensitive taurine transport in human SH‐SY5Y neuroblastoma cells DJ Foster, VM Vitvitsky, R Banerjee, AM Heacock, SK Fisher Journal of neurochemistry 108 (2), 437-449, 2009 | 11 | 2009 |
Activation of muscarinic cholinergic receptors on human SH-SY5Y neuroblastoma cells enhances both the influx and efflux of K+ under conditions of hypo-osmolarity DJ Foster, AM Heacock, RF Keep, SK Fisher The Journal of pharmacology and experimental therapeutics 325 (2), 457-465, 2008 | 10 | 2008 |
Prostanoid receptors regulate the volume-sensitive efflux of osmolytes from murine fibroblasts via a cyclic AMP-dependent mechanism AM Heacock, DJ Foster, SK Fisher The Journal of pharmacology and experimental therapeutics 319 (2), 963-971, 2006 | 8 | 2006 |