DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation F Quaglia, B Mészáros, E Salladini, A Hatos, R Pancsa, LB Chemes, ... Nucleic acids research 50 (D1), D480-D487, 2022 | 154 | 2022 |
AlphaFold and the amyloid landscape F Pinheiro, J Santos, S Ventura Journal of Molecular Biology 433 (20), 167059, 2021 | 71 | 2021 |
pH-dependent aggregation in intrinsically disordered proteins is determined by charge and lipophilicity J Santos, V Iglesias, J Santos-Suárez, M Mangiagalli, S Brocca, I Pallarès, ... Cells 9 (1), 145, 2020 | 66 | 2020 |
Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications J Santos, J Pujols, I Pallarès, V Iglesias, S Ventura Computational and structural biotechnology journal 18, 1403-1413, 2020 | 64 | 2020 |
α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity J Santos, P Gracia, S Navarro, S Peña-Díaz, J Pujols, N Cremades, ... Nature communications 12 (1), 3752, 2021 | 63 | 2021 |
DisProt in 2024: improving function annotation of intrinsically disordered proteins MC Aspromonte, MV Nugnes, F Quaglia, A Bouharoua, SCE Tosatto, ... Nucleic Acids Research 52 (D1), D434-D441, 2024 | 54 | 2024 |
Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis F Pinheiro, N Varejão, S Esperante, J Santos, A Velázquez‐Campoy, ... The FEBS Journal 288 (1), 310-324, 2021 | 52 | 2021 |
ZPD-2, a small compound that inhibits α-synuclein amyloid aggregation and its seeded polymerization S Peña-Díaz, J Pujols, M Conde-Giménez, A Čarija, E Dalfo, J García, ... Frontiers in molecular neuroscience 12, 306, 2019 | 42 | 2019 |
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses E Medina-Carmona, I Betancor-Fernández, J Santos, N Mesa-Torres, ... Human Molecular Genetics 28 (1), 1-15, 2019 | 32 | 2019 |
Inhibition of α-synuclein aggregation and mature fibril disassembling with a minimalistic compound, ZPDm S Peña-Díaz, J Pujols, F Pinheiro, J Santos, I Pallarés, S Navarro, ... Frontiers in Bioengineering and Biotechnology 8, 588947, 2020 | 21 | 2020 |
Functional amyloids germinate in plants J Santos, S Ventura Trends in plant science 26 (1), 7-10, 2021 | 19 | 2021 |
DispHred: A server to predict pH-dependent order–disorder transitions in intrinsically disordered proteins J Santos, V Iglesias, C Pintado, J Santos-Suárez, S Ventura International journal of molecular sciences 21 (16), 5814, 2020 | 19 | 2020 |
Arabidopsis metacaspase MC1 localizes in stress granules, clears protein aggregates, and delays senescence N Ruiz-Solaní, J Salguero-Linares, L Armengot, J Santos, I Pallarès, ... The Plant Cell 35 (9), 3325-3344, 2023 | 17 | 2023 |
Cryptic amyloidogenic regions in intrinsically disordered proteins: function and disease association J Santos, I Pallarès, V Iglesias, S Ventura Computational and Structural Biotechnology Journal 19, 4192-4206, 2021 | 16 | 2021 |
A targetable N-terminal motif orchestrates α-synuclein oligomer-to-fibril conversion J Santos, J Cuellar, I Pallarès, EJ Byrd, A Lends, F Moro, ... Journal of the American Chemical Society 146 (18), 12702-12711, 2024 | 15* | 2024 |
SolupHred: a server to predict the pH-dependent aggregation of intrinsically disordered proteins C Pintado, J Santos, V Iglesias, S Ventura Bioinformatics 37 (11), 1602-1603, 2021 | 15 | 2021 |
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains S Peña-Díaz, J Pujols, E Vasili, F Pinheiro, J Santos, ... Journal of Biological Chemistry 298 (5), 2022 | 14 | 2022 |
Is a cure for Parkinson’s disease hiding inside us? J Santos, I Pallarès, S Ventura Trends in Biochemical Sciences 47 (8), 641-644, 2022 | 13 | 2022 |
SGnn: a web server for the prediction of prion-like domains recruitment to stress granules upon heat stress V Iglesias, J Santos, J Santos-Suárez, C Pintado-Grima, S Ventura Frontiers in Molecular Biosciences 8, 718301, 2021 | 13 | 2021 |
Computational prediction and redesign of aberrant protein oligomerization J Santos, V Iglesias, S Ventura Progress in Molecular Biology and Translational Science 169, 43-83, 2020 | 12 | 2020 |