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Bingxu Liu
Bingxu Liu
Current: IPD, UW Past: MIT/Broad/Koch
Correu electrònic verificat a uw.edu
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Gene essentiality profiling reveals gene networks and synthetic lethal interactions with oncogenic Ras
T Wang, H Yu, NW Hughes, B Liu, A Kendirli, K Klein, WW Chen, ...
Cell 168 (5), 890-903. e15, 2017
7112017
Human STING is a proton channel
B Liu, RJ Carlson, IS Pires, M Gentili, E Feng, Q Hellier, MA Schwartz, ...
Science 381 (6657), 508-514, 2023
802023
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro
MJ Dolan, M Therrien, S Jereb, T Kamath, V Gazestani, T Atkeson, ...
Nature immunology 24 (8), 1382-1390, 2023
722023
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling
M Gentili, B Liu, M Papanastasiou, D Dele-Oni, MA Schwartz, RJ Carlson, ...
Nature communications 14 (1), 611, 2023
612023
A resource for generating and manipulating human microglial states in vitro
MJ Dolan, M Therrien, S Jereb, T Kamath, T Atkeson, SE Marsh, A Goeva, ...
BioRxiv, 2022.05. 02.490100, 2022
152022
An efficient lentiviral CRISPRi approach to silence genes in primary human monocytes
B Liu, M Gentili, D Lieb, T Eisenhaure, DJ Irvine, N Hacohen
Biorxiv, 2020.12. 23.424242, 2020
62020
Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
M Gentili, RJ Carlson, B Liu, Q Hellier, J Andrews, Y Qin, PC Blainey, ...
Cell Systems 15 (12), 1264-1277. e8, 2024
22024
ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling
M Gentili, B Liu, M Papanastasiou, D Dele-Oni, MA Schwartz, RJ Carlson, ...
bioRxiv, 2022.09. 22.509044, 2022
12022
Methods and compositions for modulating sting signaling and innate immune responses
N Hacohen, M Gentile, LIU Bingxu
US Patent App. 18/568,797, 2024
2024
Abstract 2356 Targeting Cancer peptide-MHC Neoantigens with de novo Designed Proteins
N Greenwood, A Motmaen, B Liu, D Baker
Journal of Biological Chemistry 300 (3), 2024
2024
Protons are the new first responders
B Liu
Science 383 (6684), 713-714, 2024
2024
Design of high specificity binders for peptide-MHC-I complexes
B Liu, NF Greenwood, JE Bonzanini, A Motmaen, J Sharp, C Wang, ...
bioRxiv, 2024.11. 28.625793, 2024
2024
Inheritance, innovation, and adaptation of immune systems: Regulation of the Innate Immunity Sensor Stimulator of Interferon Genes (STING)
B Liu
Massachusetts Institute of Technology, 2023
2023
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
Articles 1–13