Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring SF Zhou, CC Xue, XQ Yu, C Li, G Wang Therapeutic drug monitoring 29 (6), 687-710, 2007 | 462 | 2007 |
Farnesoid X receptor regulation of the NLRP3 inflammasome underlies cholestasis-associated sepsis H Hao, L Cao, C Jiang, Y Che, S Zhang, S Takahashi, G Wang, ... Cell metabolism 25 (4), 856-867. e5, 2017 | 385 | 2017 |
Extensive intestinal first-pass elimination and predominant hepatic distribution of berberine explain its low plasma levels in rats YT Liu, HP Hao, HG Xie, L Lai, Q Wang, CX Liu, GJ Wang Drug metabolism and disposition 38 (10), 1779-1784, 2010 | 322 | 2010 |
Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages X Zhang, G Wang, EC Gurley, H Zhou PloS one 9 (9), e107072, 2014 | 316 | 2014 |
The involvement of P‐glycoprotein in berberine absorption G Pan, GJ Wang, XD Liu, JP Fawcett, YY Xie Pharmacology & toxicology 91 (4), 193-197, 2002 | 278 | 2002 |
Gut microbial metabolites of aromatic amino acids as signals in host–microbe interplay Y Liu, Y Hou, G Wang, X Zheng, H Hao Trends in Endocrinology & Metabolism 31 (11), 818-834, 2020 | 262 | 2020 |
Drugs as CYP3A probes, inducers, and inhibitors YT Liu, HP Hao, CX Liu, GJ Wang, HG Xie Drug metabolism reviews 39 (4), 699-721, 2007 | 250 | 2007 |
The antihyperglycaemic activity of berberine arises from a decrease of glucose absorption GY Pan, ZJ Huang, GJ Wang, JP Fawcett, XD Liu, XC Zhao, JG Sun, ... Planta medica 69 (07), 632-636, 2003 | 219 | 2003 |
Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats T Lu, J Song, F Huang, Y Deng, L Xie, G Wang, X Liu Journal of Ethnopharmacology 110 (3), 412-418, 2007 | 218 | 2007 |
Betulinic acid and its derivatives as potential antitumor agents DM Zhang, HG Xu, L Wang, YJ Li, PH Sun, XM Wu, GJ Wang, WM Chen, ... Medicinal research reviews 35 (6), 1127-1155, 2015 | 216 | 2015 |
Antiobesity and antihyperglycemic effects of ginsenoside Rb1 in rats Y Xiong, L Shen, KJ Liu, P Tso, Y Xiong, G Wang, SC Woods, M Liu Diabetes 59 (10), 2505-2512, 2010 | 201 | 2010 |
Metabolic activation of herbal and dietary constituents and its clinical and toxicological implications: an update SF Zhou, CC Xue, XQ Yu, G Wang Current drug metabolism 8 (6), 526-553, 2007 | 194 | 2007 |
Herbal drug discovery for the treatment of nonalcoholic fatty liver disease T Yan, N Yan, P Wang, Y Xia, H Hao, G Wang, FJ Gonzalez Acta Pharmaceutica Sinica B 10 (1), 3-18, 2020 | 191 | 2020 |
Orally administered berberine modulates hepatic lipid metabolism by altering microbial bile acid metabolism and the intestinal FXR signaling pathway R Sun, N Yang, B Kong, B Cao, D Feng, X Yu, C Ge, J Huang, J Shen, ... Molecular pharmacology 91 (2), 110-122, 2017 | 182 | 2017 |
Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1‐phosphate receptor 2 R Liu, R Zhao, X Zhou, X Liang, DJW Campbell, X Zhang, L Zhang, R Shi, ... Hepatology 60 (3), 908-918, 2014 | 182 | 2014 |
Differences in metabolite profile between blood plasma and serum L Liu, J Aa, G Wang, B Yan, Y Zhang, X Wang, C Zhao, B Cao, J Shi, M Li, ... Analytical biochemistry 406 (2), 105-112, 2010 | 182 | 2010 |
PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis X Zhou, L Cao, C Jiang, Y Xie, X Cheng, KW Krausz, Y Qi, L Sun, ... Nature communications 5 (1), 4573, 2014 | 171 | 2014 |
Global detection and identification of nontarget components from herbal preparations by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a strategy H Hao, N Cui, G Wang, B Xiang, Y Liang, X Xu, H Zhang, J Yang, ... Analytical Chemistry 80 (21), 8187-8194, 2008 | 154 | 2008 |
Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes F Qiu, R Zhang, J Sun, A Jiye, H Hao, Y Peng, H Ai, G Wang Drug Metabolism and Disposition 36 (7), 1308-1314, 2008 | 154 | 2008 |
High performance liquid chromatographic–mass spectrometric determination of ginsenoside Rg3 and its metabolites in rat plasma using solid-phase extraction for pharmacokinetic … HT Xie, GJ Wang, JG Sun, I Tucker, XC Zhao, YY Xie, H Li, X Jiang, ... Journal of Chromatography B 818 (2), 167-173, 2005 | 152 | 2005 |