A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4769 | 2020 |
α-Synuclein impairs macroautophagy: implications for Parkinson’s disease AR Winslow, CW Chen, S Corrochano, A Acevedo-Arozena, DE Gordon, ... Journal of Cell Biology 190 (6), 1023-1037, 2010 | 1008 | 2010 |
The global phosphorylation landscape of SARS-CoV-2 infection M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ... Cell 182 (3), 685-712. e19, 2020 | 963 | 2020 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 689 | 2020 |
CRISPR interference efficiently induces specific and reversible gene silencing in human iPSCs MA Mandegar, N Huebsch, EB Frolov, E Shin, A Truong, MP Olvera, ... Cell stem cell 18 (4), 541-553, 2016 | 577 | 2016 |
Genetic interaction mapping in mammalian cells using CRISPR interference D Du, A Roguev, DE Gordon, M Chen, SH Chen, M Shales, JP Shen, ... Nature methods 14 (6), 577-580, 2017 | 179 | 2017 |
A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress MA Surma, C Klose, D Peng, M Shales, C Mrejen, A Stefanko, H Braberg, ... Molecular cell 51 (4), 519-530, 2013 | 155 | 2013 |
A targeted siRNA screen to identify SNAREs required for constitutive secretion in mammalian cells DE Gordon, LM Bond, DA Sahlender, AA Peden Traffic 11 (9), 1191-1204, 2010 | 153 | 2010 |
A genome‐wide RNA interference screen identifies two novel components of the metazoan secretory pathway F Wendler, AK Gillingham, R Sinka, C Rosa‐Ferreira, DE Gordon, ... The EMBO journal 29 (2), 304-314, 2010 | 109 | 2010 |
Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1 MY Jeng, PA Hull, M Fei, HS Kwon, CL Tsou, H Kasler, CP Ng, ... Journal of Experimental Medicine 215 (1), 51-62, 2018 | 108 | 2018 |
SARS-CoV-2 ORF9c is a membrane-associated protein that suppresses antiviral responses in cells A Dominguez Andres, Y Feng, AR Campos, J Yin, CC Yang, B James, ... BioRxiv, 2020.08. 18.256776, 2020 | 71 | 2020 |
ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection R Hüttenhain, J Xu, LA Burton, DE Gordon, JF Hultquist, JR Johnson, ... Cell host & microbe 26 (1), 86-99. e7, 2019 | 62 | 2019 |
Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins J Hiatt, DA Cavero, MJ McGregor, W Zheng, JM Budzik, TL Roth, ... Cell reports 35 (6), 2021 | 51 | 2021 |
VAMP3/Syb and YKT6 are required for the fusion of constitutive secretory carriers with the plasma membrane DE Gordon, J Chia, K Jayawardena, R Antrobus, F Bard, AA Peden PLoS Genetics 13 (4), e1006698, 2017 | 50 | 2017 |
The landscape of human cancer proteins targeted by SARS-CoV-2 B Tutuncuoglu, M Cakir, J Batra, M Bouhaddou, M Eckhardt, DE Gordon, ... Cancer discovery 10 (7), 916-921, 2020 | 49 | 2020 |
Coiled‐coil interactions are required for post‐Golgi R‐SNARE trafficking DE Gordon, M Mirza, DA Sahlender, J Jakovleska, AA Peden EMBO reports 10 (8), 851-856, 2009 | 35 | 2009 |
Willingness to use a wearable device capable of detecting and reversing overdose among people who use opioids in Philadelphia K Kanter, R Gallagher, F Eweje, A Lee, D Gordon, S Landy, J Gasior, ... Harm reduction journal 18, 1-14, 2021 | 34 | 2021 |
The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity A Gokhale, AP Mullin, SA Zlatic, CA Easley, ME Merritt, N Raj, J Larimore, ... Journal of Neuroscience 35 (19), 7643-7653, 2015 | 29 | 2015 |
CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling SH Chen, GM Jang, R Hüttenhain, DE Gordon, D Du, BW Newton, ... The EMBO journal 37 (18), e97508, 2018 | 26 | 2018 |
A quantitative genetic interaction map of HIV infection DE Gordon, A Watson, A Roguev, S Zheng, GM Jang, J Kane, J Xu, ... Molecular cell 78 (2), 197-209. e7, 2020 | 25 | 2020 |