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Dr. Andrew Pocklington
Dr. Andrew Pocklington
Senior Lecturer in Bioinformatics and Biostatistics, Cardiff University, UK
Correu electrònic verificat a cardiff.ac.uk
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Biological insights from 108 schizophrenia-associated genetic loci
C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ...
Nature 511 (7510), 421-427, 2014
77572014
De novo mutations in schizophrenia implicate synaptic networks
M Fromer, AJ Pocklington, DH Kavanagh, HJ Williams, S Dwyer, ...
Nature 506 (7487), 179-184, 2014
18592014
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ...
Nature 604 (7906), 502-508, 2022
17512022
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
AF Pardiñas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ...
Nature genetics 50 (3), 381-389, 2018
16292018
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
14542015
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
CR Marshall, DP Howrigan, D Merico, B Thiruvahindrapuram, W Wu, ...
Nature genetics 49 (1), 27-35, 2017
10042017
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
G Kirov, AJ Pocklington, P Holmans, D Ivanov, M Ikeda, D Ruderfer, ...
Molecular psychiatry 17 (2), 142-153, 2012
9702012
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ...
The American Journal of Human Genetics 95 (5), 535-552, 2014
6852014
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ...
Cell 173 (7), 1705-1715. e16, 2018
5692018
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease
L Jones, PA Holmans, ML Hamshere, D Harold, V Moskvina, D Ivanov, ...
PloS one 5 (11), e13950, 2010
4682010
Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes
SE Morgan, J Seidlitz, KJ Whitaker, R Romero-Garcia, NE Clifton, ...
Proceedings of the National Academy of Sciences 116 (19), 9604-9609, 2019
2992019
Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia
AJ Pocklington, E Rees, JTR Walters, J Han, DH Kavanagh, KD Chambert, ...
Neuron 86 (5), 1203-1214, 2015
2452015
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
B Franke, JL Stein, S Ripke, V Anttila, DP Hibar, KJE Van Hulzen, ...
Nature neuroscience 19 (3), 420-431, 2016
2402016
Evolutionary expansion and anatomical specialization of synapse proteome complexity
RD Emes, AJ Pocklington, CNG Anderson, A Bayes, MO Collins, ...
Nature neuroscience 11 (7), 799-806, 2008
2342008
Complement genes contribute sex-biased vulnerability in diverse disorders
N Kamitaki, A Sekar, RE Handsaker, H De Rivera, K Tooley, DL Morris, ...
Nature 582 (7813), 577-581, 2020
2072020
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts
G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ...
Biological psychiatry 90 (9), 611-620, 2021
1692021
Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood
G Ni, G Moser, S Ripke, BM Neale, A Corvin, JTR Walters, KH Farh, ...
The American Journal of Human Genetics 102 (6), 1185-1194, 2018
1652018
Analysis of intellectual disability copy number variants for association with schizophrenia
E Rees, K Kendall, AF Pardiñas, SE Legge, A Pocklington, V Escott-Price, ...
JAMA psychiatry 73 (9), 963-969, 2016
1652016
Neurotransmitters drive combinatorial multistate postsynaptic density networks
MP Coba, AJ Pocklington, MO Collins, MV Kopanitsa, RT Uren, S Swamy, ...
Science signaling 2 (68), ra19-ra19, 2009
1532009
The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour
AJ Pocklington, M Cumiskey, JD Armstrong, SGN Grant
Molecular systems biology 2 (1), 2006.0023, 2006
1492006
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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