| Insulin receptor signaling in normal and insulin-resistant states J Boucher, A Kleinridders, CR Kahn Cold Spring Harbor perspectives in biology 6 (1), a009191, 2014 | 1804 | 2014 |
| Insulin action in brain regulates systemic metabolism and brain function A Kleinridders, HA Ferris, W Cai, CR Kahn Diabetes 63 (7), 2232-2243, 2014 | 757 | 2014 |
| MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity A Kleinridders, D Schenten, AC Könner, BF Belgardt, J Mauer, T Okamura, ... Cell metabolism 10 (4), 249-259, 2009 | 567 | 2009 |
| Insulin resistance in brain alters dopamine turnover and causes behavioral disorders A Kleinridders, W Cai, L Cappellucci, A Ghazarian, WR Collins, ... Proceedings of the National Academy of Sciences 112 (11), 3463-3468, 2015 | 467 | 2015 |
| Trimethylamine N-oxide binds and activates PERK to promote metabolic dysfunction S Chen, A Henderson, MC Petriello, KA Romano, M Gearing, J Miao, ... Cell metabolism 30 (6), 1141-1151. e5, 2019 | 313 | 2019 |
| Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation E Jing, BT O’Neill, MJ Rardin, A Kleinridders, OR Ilkeyeva, S Ussar, ... Diabetes 62 (10), 3404-3417, 2013 | 287 | 2013 |
| Myeloid-cell-derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity A Jais, M Solas, H Backes, B Chaurasia, A Kleinridders, S Theurich, ... Cell 165 (4), 882-895, 2016 | 260 | 2016 |
| Riboflavin kinase couples TNF receptor 1 to NADPH oxidase B Yazdanpanah, K Wiegmann, V Tchikov, O Krut, C Pongratz, ... Nature 460 (7259), 1159-1163, 2009 | 253 | 2009 |
| ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes S Ussar, KY Lee, SN Dankel, J Boucher, MF Haering, A Kleinridders, ... Science translational medicine 6 (247), 247ra103-247ra103, 2014 | 227 | 2014 |
| Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and InsulinSignaling in Obesity MB Ernst, CM Wunderlich, S Hess, M Paehler, A Mesaros, SB Koralov, ... Journal of Neuroscience 29 (37), 11582-11593, 2009 | 225 | 2009 |
| Insulin regulates astrocyte gliotransmission and modulates behavior W Cai, C Xue, M Sakaguchi, M Konishi, A Shirazian, HA Ferris, ME Li, ... The Journal of clinical investigation 128 (7), 2914-2926, 2018 | 216 | 2018 |
| Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis AC Könner, S Hess, S Tovar, A Mesaros, C Sánchez-Lasheras, N Evers, ... Cell metabolism 13 (6), 720-728, 2011 | 199 | 2011 |
| Central nervous pathways of insulin action in the control of metabolism and food intake S Kullmann, A Kleinridders, DM Small, A Fritsche, HU Häring, H Preissl, ... The lancet Diabetes & endocrinology 8 (6), 524-534, 2020 | 194 | 2020 |
| Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression W Cai, M Sakaguchi, A Kleinridders, G Gonzalez-Del Pino, JM Dreyfuss, ... Nature communications 8 (1), 14892, 2017 | 175 | 2017 |
| Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis BT O’Neill, KY Lee, K Klaus, S Softic, MT Krumpoch, J Fentz, KI Stanford, ... The Journal of clinical investigation 126 (9), 3433-3446, 2016 | 170 | 2016 |
| Differential roles of insulin and IGF-1 receptors in adipose tissue development and function J Boucher, S Softic, A El Ouaamari, MT Krumpoch, A Kleinridders, ... Diabetes 65 (8), 2201-2213, 2016 | 156 | 2016 |
| Leptin regulation of Hsp60 impacts hypothalamic insulin signaling A Kleinridders, HPMM Lauritzen, S Ussar, JH Christensen, MA Mori, ... The Journal of clinical investigation 123 (11), 4667-4680, 2013 | 150 | 2013 |
| Reversible gene knockdown in mice using a tight, inducible shRNA expression system J Seibler, A Kleinridders, B Küter-Luks, S Niehaves, JC Brüning, ... Nucleic acids research 35 (7), e54, 2007 | 148 | 2007 |
| Hepatic Bax inhibitor-1 inhibits IRE1α and protects from obesity-associated insulin resistance and glucose intolerance B Bailly-Maitre, BF Belgardt, SD Jordan, B Coornaert, MJ von Freyend, ... Journal of Biological Chemistry 285 (9), 6198-6207, 2010 | 135 | 2010 |
| Secondary consequences of β cell inexcitability: identification and prevention in a murine model of KATP-induced neonatal diabetes mellitus MS Remedi, HT Kurata, A Scott, FT Wunderlich, E Rother, A Kleinridders, ... Cell metabolism 9 (2), 140-151, 2009 | 108 | 2009 |
