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Jacklyn N. Hellwege
Jacklyn N. Hellwege
Research Assistant Professor, Division of Genetic Medicine, Vanderbilt University Medical Center
Correu electrònic verificat a vanderbilt.edu
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ...
Nature genetics 50 (10), 1412-1425, 2018
13562018
A catalog of genetic loci associated with kidney function from analyses of a million individuals
M Wuttke, Y Li, M Li, KB Sieber, MF Feitosa, M Gorski, A Tin, L Wang, ...
Nature genetics 51 (6), 957-972, 2019
7192019
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
A Giri, JN Hellwege, JM Keaton, J Park, C Qiu, HR Warren, ES Torstenson, ...
Nature genetics 51 (1), 51-62, 2019
4162019
Population stratification in genetic association studies
JN Hellwege, JM Keaton, A Giri, X Gao, DR Velez Edwards, TL Edwards
Current protocols in human genetics 95 (1), 1.22. 1-1.22. 23, 2017
2572017
Obesity and pelvic organ prolapse: a systematic review and meta-analysis of observational studies
A Giri, KE Hartmann, JN Hellwege, DRV Edwards, TL Edwards
American journal of obstetrics and gynecology 217 (1), 11-26. e3, 2017
1752017
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
P Surendran, EV Feofanova, N Lahrouchi, I Ntalla, S Karthikeyan, J Cook, ...
Nature genetics 52 (12), 1314-1332, 2020
1582020
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale, Z Miao, MJ Seasock, ...
Nature genetics 53 (9), 1322-1333, 2021
1212021
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program
JN Hellwege, DR Velez Edwards, A Giri, C Qiu, J Park, ES Torstenson, ...
Nature communications 10 (1), 3842, 2019
1182019
Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans
JN Cooke, MA Bostrom, PJ Hicks, MCY Ng, JN Hellwege, ME Comeau, ...
Nephrology Dialysis Transplantation 27 (4), 1505-1511, 2012
1062012
Genome-wide polygenic score to predict chronic kidney disease across ancestries
A Khan, MC Turchin, A Patki, V Srinivasasainagendra, N Shang, ...
Nature medicine 28 (7), 1412-1420, 2022
1042022
Relationship between blood pressure and incident cardiovascular disease: linear and nonlinear Mendelian randomization analyses
R Malik, MK Georgakis, M Vujkovic, SM Damrauer, P Elliott, V Karhunen, ...
Hypertension 77 (6), 2004-2013, 2021
762021
Returning integrated genomic risk and clinical recommendations: The eMERGE study
JE Linder, A Allworth, HT Bland, PJ Caraballo, RL Chisholm, EW Clayton, ...
Genetics in Medicine 25 (4), 100006, 2023
722023
Genetic risk score is associated with prevalence of advanced neoplasms in a colorectal cancer screening population
K Weigl, H Thomsen, Y Balavarca, JN Hellwege, MJ Shrubsole, ...
Gastroenterology 155 (1), 88-98. e10, 2018
702018
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants
A Wang, J Shen, AA Rodriguez, EJ Saunders, F Chen, R Janivara, ...
Nature genetics 55 (12), 2065-2074, 2023
622023
Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics
JN Hellwege, ND Palmer, JT Ziegler, CD Langefeld, C Lorenzo, JM Norris, ...
Gene 534 (1), 33-39, 2014
592014
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis
Y Guan, X Liang, Z Ma, H Hu, H Liu, Z Miao, A Linkermann, JN Hellwege, ...
Nature communications 12 (1), 5078, 2021
552021
A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids
TL Edwards, A Giri, JN Hellwege, KE Hartmann, EA Stewart, JM Jeff, ...
Frontiers in Genetics 10, 511, 2019
542019
A multi-stage genome-wide association study of uterine fibroids in African Americans
JN Hellwege, JM Jeff, LA Wise, CS Gallagher, M Wellons, KE Hartmann, ...
Human genetics 136, 1363-1373, 2017
542017
Heritability and genome-wide association study of benign prostatic hyperplasia (BPH) in the eMERGE network
JN Hellwege, S Stallings, ES Torstenson, R Carroll, KM Borthwick, ...
Scientific reports 9 (1), 6077, 2019
342019
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
JM Keaton, Z Kamali, T Xie, A Vaez, A Williams, SB Goleva, A Ani, ...
Nature genetics, 1-14, 2024
332024
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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