Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis BL Jutras, RB Lochhead, ZA Kloos, J Biboy, K Strle, CJ Booth, SK Govers, ... Proceedings of the National Academy of Sciences 116 (27), 13498-13507, 2019 | 164 | 2019 |
Lyme arthritis: linking infection, inflammation and autoimmunity RB Lochhead, K Strle, SL Arvikar, JJ Weis, AC Steere Nature Reviews Rheumatology 17 (8), 449-461, 2021 | 109 | 2021 |
Quorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidius MH Pontes, M Babst, R Lochhead, K Oakeson, K Smith, C Dale PloS one 3 (10), e3541, 2008 | 57 | 2008 |
MicroRNA-146a Provides Feedback Regulation of Lyme Arthritis but Not Carditis during Infection with Borrelia burgdorferi RB Lochhead, Y Ma, JF Zachary, D Baltimore, JL Zhao, JH Weis, ... PLoS pathogens 10 (6), e1004212, 2014 | 51 | 2014 |
Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected … RB Lochhead, FL Sonderegger, Y Ma, JE Brewster, D Cornwall, ... The Journal of Immunology 189 (5), 2488-2501, 2012 | 48 | 2012 |
Interferon‐gamma production in Lyme arthritis synovial tissue promotes differentiation of fibroblast‐like synoviocytes into immune effector cells RB Lochhead, D Ordoñez, SL Arvikar, JM Aversa, LS Oh, B Heyworth, ... Cellular microbiology 21 (2), e12992, 2019 | 47 | 2019 |
Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with postinfectious, Borrelia burgdorferi‐induced Lyme … RB Lochhead, SL Arvikar, JM Aversa, RI Sadreyev, K Strle, AC Steere Cellular microbiology 21 (2), e12954, 2019 | 47 | 2019 |
MicroRNA expression shows inflammatory dysregulation and tumor‐like proliferative responses in joints of patients with postinfectious Lyme arthritis RB Lochhead, K Strle, ND Kim, MJ Kohler, SL Arvikar, JM Aversa, ... Arthritis & Rheumatology 69 (5), 1100-1110, 2017 | 44 | 2017 |
Borrelia burgdorferi Arthritis–Associated Locus Bbaa1 Regulates Lyme Arthritis and K/B× N Serum Transfer Arthritis through Intrinsic Control of Type I IFN Production Y Ma, KKC Bramwell, RB Lochhead, JK Paquette, JF Zachary, JH Weis, ... The Journal of Immunology 193 (12), 6050-6060, 2014 | 32 | 2014 |
Antagonistic interplay between microRNA-155 and IL-10 during Lyme carditis and arthritis RB Lochhead, JF Zachary, L Dalla Rosa, Y Ma, JH Weis, RM O’Connell, ... PLoS One 10 (8), e0135142, 2015 | 31 | 2015 |
Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis K Kanjana, K Strle, RB Lochhead, A Pianta, LM Mateyka, Q Wang, ... The Journal of Clinical Investigation 133 (17), 2023 | 19 | 2023 |
Correlation of Lyme disease–associated IgG4 autoantibodies with synovial pathology in antibiotic‐refractory Lyme arthritis KB Sulka, K Strle, JT Crowley, RB Lochhead, R Anthony, AC Steere Arthritis & Rheumatology 70 (11), 1835-1846, 2018 | 19 | 2018 |
Report of the pathogenesis and pathophysiology of Lyme disease subcommittee of the HHS Tick Borne Disease Working Group ST Donta, LJ States, WA Adams, T Bankhead, N Baumgarth, ME Embers, ... Frontiers in Medicine 8, 643235, 2021 | 12 | 2021 |
Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation MN Holub, A Wahhab, JR Rouse, R Danner, LG Hackner, CB Duris, ... Arthritis Research & Therapy 26 (1), 77, 2024 | 10 | 2024 |
Cell‐Mediated Cytotoxicity in Lyme Arthritis D Ordóñez, RB Lochhead, K Strle, A Pianta, S Arvikar, I Van Rhijn, ... Arthritis & Rheumatology 75 (5), 782-793, 2023 | 6 | 2023 |
HLA‐DR–Expressing Fibroblast‐Like Synoviocytes Are Inducible Antigen Presenting Cells That Present Autoantigens in Lyme Arthritis JR Rouse, R Danner, A Wahhab, M Pereckas, C Nguyen, ME McClune, ... ACR open rheumatology 6 (10), 678-689, 2024 | 3 | 2024 |
Immune fibroblasts are unconventional antigen presenting cells and nonprofessional phagocytes in Lyme arthritis RB Lochhead, R Danner, A Wahhab, J Rouse The Journal of Immunology 204 (1_Supplement), 148.29-148.29, 2020 | 2 | 2020 |
Extracellular micrornas in synovial fluid reveal a marked proliferative signature in patients with antibiotic-refractory lyme arthritis RB Lochhead, ND Kim, S Arvikar, K Strle, AC Steere ARTHRITIS & RHEUMATOLOGY 67, 2015 | 2 | 2015 |
Identification of Major Histocompatibility Complex Class II Epitopes From Lyme Autoantigen Apolipoprotein B-100 and Borrelia burgdorferi Mcp4 in Murine Lyme … R Danner, LM Prochniak, M Pereckas, JR Rouse, A Wahhab, LG Hackner, ... The Journal of Infectious Diseases 230 (Supplement_1), S27-S39, 2024 | 1 | 2024 |
Human leukocyte antigen HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis JR Rouse, R Danner, A Wahhab, M Pereckas, ME McClune, AC Steere, ... bioRxiv, 2023 | 1 | 2023 |