Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin JA Rohde, O Roopnarine, DD Thomas, JM Muretta Proceedings of the National Academy of Sciences 115 (32), E7486-E7494, 2018 | 154 | 2018 |
The mechanism of force generation in myosin: a disorder-to-order transition, coupled to internal structural changes DD Thomas, S Ramachandran, O Roopnarine, DW Hayden, EM Ostap Biophysical journal 68 (4 Suppl), 135S, 1995 | 115 | 1995 |
Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy O Roopnarine, LA Leinwand Biophysical journal 75 (6), 3023-3030, 1998 | 74 | 1998 |
Orientation of intermediate nucleotide states of indane dione spin-labeled myosin heads in muscle fibers O Roopnarine, DD Thomas Biophysical journal 70 (6), 2795-2806, 1996 | 60 | 1996 |
Microsecond rotational dynamics of spin-labeled myosin regulatory light chain induced by relaxation and contraction of scallop muscle O Roopnarine, AG Szent-Györgyi, DD Thomas Biochemistry 37 (41), 14428-14436, 1998 | 44 | 1998 |
Context specific misreading of phenylalanine codons J Precup, AK Ulrich, O Roopnarine, J Parker Molecular and General Genetics MGG 218, 397-401, 1989 | 43 | 1989 |
Changes in actin and myosin structural dynamics due to their weak and strong interactions DD Thomas, E Prochniewicz, O Roopnarine Molecular Interactions of Actin: Actin-Myosin Interaction and Actin-Based …, 2002 | 38 | 2002 |
Mechanical defects of muscle fibers with myosin light chain mutants that cause cardiomyopathy O Roopnarine Biophysical journal 84 (4), 2440-2449, 2003 | 31 | 2003 |
Orientational dynamics of indane dione spin-labeled myosin heads in relaxed and contracting skeletal muscle fibers O Roopnarine, DD Thomas Biophysical journal 68 (4), 1461-1471, 1995 | 30 | 1995 |
Saturation transfer electron parametric resonance of an indane-dione spin-label. Calibration with hemoglobin and application to myosin rotational dynamics O Roopnarine, K Hideg, DD Thomas Biophysical journal 64 (6), 1896-1907, 1993 | 26 | 1993 |
A cardiomyopathy mutation in the myosin essential light chain alters actomyosin structure P Guhathakurta, E Prochniewicz, O Roopnarine, JA Rohde, DD Thomas Biophysical journal 113 (1), 91-100, 2017 | 23 | 2017 |
A spin label that binds to myosin heads in muscle fibers with its principal axis parallel to the fiber axis O Roopnarine, DD Thomas Biophysical journal 67 (4), 1634-1645, 1994 | 22 | 1994 |
A large-scale high-throughput screen for modulators of SERCA activity PA Bidwell, SL Yuen, J Li, K Berg, RT Rebbeck, CC Aldrich, ... Biomolecules 12 (12), 1789, 2022 | 17 | 2022 |
Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators O Roopnarine, SL Yuen, AR Thompson, LN Roelike, RT Rebbeck, ... Scientific reports 13 (1), 10673, 2023 | 9 | 2023 |
Interaction of DWORF with SERCA and PLB as determined by EPR spectroscopy MD Rustad, O Roopnarine, RL Cornea, DD Thomas Biochemical and biophysical research communications 645, 97-102, 2023 | 9 | 2023 |
Saturation transfer EPR spectroscopy with an indane dione spin label: calibration with hemoglobin and application to myosin rotational dynamics O Roopnarine, K Hideg, DD Thomas Biophys. J 64, 1986-1907, 1993 | 9 | 1993 |
Mechanistic analysis of actin-binding compounds that affect the kinetics of cardiac myosin–actin interaction O Roopnarine, DD Thomas Journal of Biological Chemistry 296, 2021 | 4 | 2021 |
An Overview of the Actin-Myosin Interaction DD Thomas, O Roopnarine Molecular Interactions of Actin: Actin-Myosin Interaction and Actin-Based …, 2002 | 4 | 2002 |
Saturation Transfer Electron Paramagnetic Resonance of Spin-Labeled Myosin Regulatory Light Chains in Contracting Muscle Fiber Bundles O Roopnarine, AG Szent-Györgyi, DD Thomas Biophysical Journal 68 (4 Suppl), 337s, 1995 | 4 | 1995 |
MUSCLE-CONTRACTION STUDIED WITH AN INDANE DIONE SPIN LABEL PROBING MYOSIN HEAVY AND LIGHT-CHAINS O Roopnarine, K Hideg, AG SZENTGYORGYI, DD Thomas BIOPHYSICAL JOURNAL 64 (2), A231-A231, 1993 | 3 | 1993 |