Codon and codon-pair usage tables (CoCoPUTs): facilitating genetic variation analyses and recombinant gene design A Alexaki, J Kames, DD Holcomb, J Athey, LV Santana-Quintero, ... Journal of molecular biology 431 (13), 2434-2441, 2019 | 142 | 2019 |
Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies A Alexaki, GK Hettiarachchi, JC Athey, UK Katneni, V Simhadri, ... Scientific reports 9 (1), 15449, 2019 | 61 | 2019 |
Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design J Kames, DD Holcomb, O Kimchi, M DiCuccio, N Hamasaki-Katagiri, ... Scientific reports 10 (1), 15643, 2020 | 58 | 2020 |
TissueCoCoPUTs: novel human tissue-specific codon and codon-pair usage tables based on differential tissue gene expression J Kames, A Alexaki, DD Holcomb, LV Santana-Quintero, JC Athey, ... Journal of molecular biology 432 (11), 3369-3378, 2020 | 35 | 2020 |
A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity R Hunt, G Hettiarachchi, U Katneni, N Hernandez, D Holcomb, J Kames, ... International journal of molecular sciences 20 (22), 5734, 2019 | 26 | 2019 |
Gene variants of coagulation related proteins that interact with SARS-CoV-2 D Holcomb, A Alexaki, N Hernandez, R Hunt, K Laurie, J Kames, ... PLoS computational biology 17 (3), e1008805, 2021 | 23 | 2021 |
Translational and transcriptional responses in human primary hepatocytes under hypoxia GK Hettiarachchi, UK Katneni, RC Hunt, JM Kames, JC Athey, H Bar, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 316 (6 …, 2019 | 21 | 2019 |
Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage D Meyer, J Kames, H Bar, AA Komar, A Alexaki, J Ibla, RC Hunt, ... Genome Medicine 13, 1-18, 2021 | 13 | 2021 |
Structural, functional, and immunogenicity implications of F9 gene recoding UK Katneni, A Alexaki, RC Hunt, N Hamasaki-Katagiri, GK Hettiarachchi, ... Blood Advances 6 (13), 3932-3944, 2022 | 10 | 2022 |
New approaches to predict the effect of co-occurring variants on protein characteristics D Holcomb, N Hamasaki-Katagiri, K Laurie, U Katneni, J Kames, ... The American Journal of Human Genetics 108 (8), 1502-1511, 2021 | 8 | 2021 |
In silico evaluation of cyclophilin inhibitors as potential treatment for SARS-COV-2 K Laurie, D Holcomb, J Kames, AA Komar, M DiCuccio, JC Ibla, ... Open Forum Infectious Diseases 8 (6), ofab189, 2021 | 7 | 2021 |
Synonymous ADAMTS13 variants impact molecular characteristics and contribute to variability in active protein abundance KI Jankowska, D Meyer, DD Holcomb, J Kames, N Hamasaki-Katagiri, ... Blood advances 6 (18), 5364-5378, 2022 | 4 | 2022 |
Ribosome profiling of HEK293T cells overexpressing codon optimized coagulation factor IX A Alexaki, J Kames, GK Hettiarachchi, JC Athey, UK Katneni, RC Hunt, ... F1000Research 9, 2020 | 4 | 2020 |
Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer S Clavé, JB Jackson, M Salido, J Kames, KMR Gerding, EL Verner, ... Frontiers in Oncology 13, 1225646, 2023 | 3 | 2023 |
Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2 D Holcomb, A Alexaki, N Hernandez, K Laurie, J Kames, ... bioRxiv, 2020.09. 08.272328, 2020 | 3 | 2020 |
Protocol to identify host-viral protein interactions between coagulation-related proteins and their genetic variants with SARS-CoV-2 proteins DD Holcomb, KI Jankowska, N Hernandez, K Laurie, J Kames, ... STAR protocols 3 (3), 101648, 2022 | 1 | 2022 |
Complimentary use of DNA-and RNA-based NGS assays optimizes detection of clinically relevant translocations for comprehensive genomic profiling R Ren, J Jackson, J Kames, D Riles, C Coldren, S Wheeler, P Chandra, ... Cancer Research 83 (7_Supplement), 5452-5452, 2023 | | 2023 |
SYNONYMOUS ADAMTS13 VARIANTS IMPACT MOLECULAR CHARACTERISTICS AND CONTRIBUTE TO VARIABILITY IN ACTIVE PROTEIN ABUNDANCE KI Jankowska, D Meyer, DD Holcomb, J Kames, N Katagiri, ... AMERICAN JOURNAL OF HEMATOLOGY 98, E49-E50, 2023 | | 2023 |
Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer B Sun, E Arriola, S Clavé, JB Jackson, M Salido, J Kames, KMR Gerding, ... | | 2023 |
Ribosome profiling of HEK293T cells overexpressin g codon optimized coagulation factor IX [version 2; peer review A Alexaki, J Kames, GK Hettiarachchi, JC Athey, UK Katneni, RC Hunt, ... | | 2020 |