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Laura E. Newman
Laura E. Newman
Assistant Professor of Cell Biology, UVA
Correu electrònic verificat a virginia.edu - Pàgina d'inici
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Mitochondrial DNA stress signalling protects the nuclear genome
Z Wu, S Oeck, AP West, KC Mangalhara, AG Sainz, LE Newman, ...
Nature metabolism 1 (12), 1209-1218, 2019
1142019
Mitohormesis in mice via sustained basal activation of mitochondrial and antioxidant signaling
CS Cox, SE McKay, MA Holmbeck, BE Christian, AC Scortea, AJ Tsay, ...
Cell metabolism 28 (5), 776-786. e5, 2018
1142018
Mitochondrial DNA release in innate immune signaling
LE Newman, GS Shadel
Annual review of biochemistry 92 (1), 299-332, 2023
952023
Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration
LE Newman, GS Shadel
The Journal of cell biology 217 (10), 3327, 2018
642018
The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels
LE Newman, C Zhou, S Mudigonda, AL Mattheyses, E Paradies, ...
PloS one 9 (6), e99270, 2014
482014
A trimer consisting of the tubulin-specific chaperone D (TBCD), regulatory GTPase ARL2, and β-tubulin is required for maintaining the microtubule network
JW Francis, LE Newman, LA Cunningham, RA Kahn
Journal of Biological Chemistry 292 (10), 4336-4349, 2017
462017
The polyadenosine RNA-binding protein, zinc finger Cys3His protein 14 (ZC3H14), regulates the pre-mRNA processing of a key ATP synthase subunit mRNA
CP Wigington, KJ Morris, LE Newman, AH Corbett
Journal of Biological Chemistry 291 (43), 22442-22459, 2016
342016
Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal
LE Newman, S Weiser Novak, GR Rojas, N Tadepalle, CR Schiavon, ...
Nature cell biology 26 (2), 194-206, 2024
322024
Oligomerization of the Sec7 domain Arf guanine nucleotide exchange factor GBF1 is dispensable for Golgi localization and function but regulates degradation
JM Bhatt, EG Viktorova, T Busby, P Wyrozumska, LE Newman, H Lin, ...
American Journal of Physiology-Cell Physiology 310 (6), C456-C469, 2016
272016
ELMOD2 regulates mitochondrial fusion in a mitofusin-dependent manner, downstream of ARL2
CR Schiavon, RE Turn, LE Newman, RA Kahn
Molecular biology of the cell 30 (10), 1198-1213, 2019
232019
The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space
LE Newman, CR Schiavon, RE Turn, RA Kahn
Cellular logistics 7 (3), e1340104, 2017
232017
Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions
JW Francis, RE Turn, LE Newman, C Schiavon, RA Kahn
Small GTPases 7 (4), 188-196, 2016
222016
The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors
LE Newman, CR Schiavon, C Zhou, RA Kahn
PloS one 12 (4), e0175164, 2017
212017
Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
I Al Khatib, J Deng, Y Lei, S Torres-Odio, GR Rojas, LE Newman, ...
Human Molecular Genetics 32 (15), 2422-2440, 2023
182023
Plasmids for variable expression of proteins targeted to the mitochondrial matrix or intermembrane space
LE Newman, C Schiavon, RA Kahn
Cellular logistics 6 (4), e1247939, 2016
182016
The biology of aging in a social world: insights from free-ranging rhesus macaques
LE Newman, C Testard, AR DeCasien, KL Chiou, MM Watowich, ...
Neuroscience & Biobehavioral Reviews 154, 105424, 2023
132023
Intrasexual male competition
LE Newman, JP Higham
Encyclopedia of Evolutionary Psychological Science, 4204-4209, 2021
42021
Endosomal removal and disposal of dysfunctional, immunostimulatory mitochondrial DNA
LE Newman, N Tadepalle, SW Novak, CR Schiavon, GR Rojas, ...
bioRxiv, 2022.10. 12.511955, 2022
32022
Social Status is Associated with Impaired Anti-Inflammatory Response in Free-Ranging Male Rhesus Macaques
MR Sanchez Rosado, L Newman, M Watowich, M Pavez-Fox, JND Valle, ...
The Journal of Immunology 210 (Supplement_1), 248.13-248.13, 2023
12023
Conserved and distinct signatures of transcriptional aging across tissues in rhesus macaques
LE Newman
American Journal of Biological Anthropology 180 (S75), 2023
2023
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
Articles 1–20