| Parkin-independent mitophagy controls chemotherapeutic response in cancer cells E Villa, E Proïcs, C Rubio-Patiño, S Obba, B Zunino, JP Bossowski, ... Cell reports 20 (12), 2846-2859, 2017 | 275 | 2017 |
| Cancer cells tune the signaling pathways to empower de novo synthesis of nucleotides E Villa, ES Ali, U Sahu, I Ben-Sahra Cancers 11 (5), 688, 2019 | 248 | 2019 |
| No Parkin zone: mitophagy without Parkin E Villa, S Marchetti, JE Ricci Trends in cell biology 28 (11), 882-895, 2018 | 219 | 2018 |
| CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis EC Genin, M Plutino, S Bannwarth, E Villa, E Cisneros‐Barroso, M Roy, ... EMBO molecular medicine 8 (1), 58-72, 2016 | 206 | 2016 |
| mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis E Villa, U Sahu, BP O’Hara, ES Ali, KA Helmin, JM Asara, P Gao, ... Molecular cell 81 (10), 2076-2093. e9, 2021 | 129 | 2021 |
| Low-protein diet induces IRE1α-dependent anticancer immunosurveillance C Rubio-Patino, JP Bossowski, GM De Donatis, L Mondragon, E Villa, ... Cell Metabolism 27 (4), 828-842. e7, 2018 | 125 | 2018 |
| Hyperthermic intraperitoneal chemotherapy leads to an anticancer immune response via exposure of cell surface heat shock protein 90 B Zunino, C Rubio-Patiño, E Villa, O Meynet, E Proics, A Cornille, ... Oncogene 35 (2), 261-268, 2016 | 80 | 2016 |
| GAPDH expression predicts the response to R-CHOP, the tumor metabolic status, and the response of DLBCL patients to metabolic inhibitors J Chiche, J Reverso-Meinietti, A Mouchotte, C Rubio-Patiño, R Mhaidly, ... Cell metabolism 29 (6), 1243-1257. e10, 2019 | 77 | 2019 |
| ERK2 phosphorylates PFAS to mediate posttranslational control of de novo purine synthesis ES Ali, U Sahu, E Villa, BP O’Hara, P Gao, C Beaudet, AW Wood, ... Molecular cell 78 (6), 1178-1191. e6, 2020 | 56 | 2020 |
| Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases EC Genin, S Bannwarth, F Lespinasse, B Ortega-Vila, K Fragaki, K Itoh, ... Neurobiology of Disease 119, 159-171, 2018 | 56 | 2018 |
| GAPDH overexpression in the T cell lineage promotes angioimmunoblastic T cell lymphoma through an NF-κB-dependent mechanism L Mondragón, R Mhaidly, GM De Donatis, M Tosolini, P Dao, AR Martin, ... Cancer Cell 36 (3), 268-287. e10, 2019 | 54 | 2019 |
| Glucose metabolism is inhibited by caspases upon the induction of apoptosis LA Pradelli, E Villa, B Zunino, S Marchetti, JE Ricci Cell death & disease 5 (9), e1406-e1406, 2014 | 53 | 2014 |
| Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway MH Soflaee, R Kesavan, U Sahu, A Tasdogan, E Villa, Z Djabari, F Cai, ... Nature communications 13 (1), 2698, 2022 | 44 | 2022 |
| Inactivation of Pif1 helicase causes a mitochondrial myopathy in mice S Bannwarth, L Berg-Alonso, G Augé, K Fragaki, JE Kolesar, ... Mitochondrion 30, 126-137, 2016 | 36 | 2016 |
| How does metabolism affect cell death in cancer? E Villa, JE Ricci The FEBS Journal 283 (14), 2653-2660, 2016 | 36 | 2016 |
| The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim LE Aira, E Villa, P Colosetti, P Gamas, L Signetti, S Obba, E Proics, ... Oncogene 37 (16), 2122-2136, 2018 | 15 | 2018 |
| Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis U Sahu, E Villa, CR Reczek, Z Zhao, BP O’Hara, MD Torno, R Mishra, ... Science 383 (6690), 1484-1492, 2024 | 13 | 2024 |
| The E3 ligase UBR2 regulates cell death under caspase deficiency via Erk/MAPK pathway E Villa, R Paul, O Meynet, S Volturo, G Pinna, JE Ricci Cell Death & Disease 11 (12), 1041, 2020 | 12 | 2020 |
| Pharmacological preconditioning protects from ischemia/reperfusion‐induced apoptosis by modulating Bcl‐xL expression through a ROS‐dependent mechanism R Rozier, R Paul, B Madji Hounoum, E Villa, R Mhaidly, J Chiche, ... The FEBS Journal 288 (11), 3547-3569, 2021 | 10 | 2021 |
| ASS1igning purine dependency to cancer E Villa, I Ben-Sahra Nature Cancer 1 (9), 862-863, 2020 | 2 | 2020 |