Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature neuroscience 25 (2), 213-225, 2022 | 363 | 2022 |
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis AP Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, ... Nature genetics 53 (2), 143-146, 2021 | 271 | 2021 |
Brain proteome-wide association study implicates novel proteins in depression pathogenesis TS Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, ... Nature neuroscience 24 (6), 810-817, 2021 | 134 | 2021 |
Shared proteomic effects of cerebral atherosclerosis and Alzheimer’s disease on the human brain AP Wingo, W Fan, DM Duong, ES Gerasimov, EB Dammer, Y Liu, ... Nature neuroscience 23 (6), 696-700, 2020 | 131 | 2020 |
Shared mechanisms across the major psychiatric and neurodegenerative diseases TS Wingo, Y Liu, ES Gerasimov, SM Vattathil, ME Wynne, J Liu, A Lori, ... Nature communications 13 (1), 4314, 2022 | 108 | 2022 |
Genetic control of the human brain proteome C Robins, Y Liu, W Fan, DM Duong, J Meigs, NV Harerimana, ... The American Journal of Human Genetics 108 (3), 400-410, 2021 | 91 | 2021 |
Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia TS Wingo, J Yang, W Fan, S Min Canon, ES Gerasimov, A Lori, ... NPJ genomic medicine 5 (1), 6, 2020 | 51 | 2020 |
Genetic evidence supporting a causal role of depression in Alzheimer’s disease NV Harerimana, Y Liu, ES Gerasimov, D Duong, TG Beach, EM Reiman, ... Biological psychiatry 92 (1), 25-33, 2022 | 50 | 2022 |
Benchmarking of computational error-correction methods for next-generation sequencing data K Mitchell, JJ Brito, I Mandric, Q Wu, S Knyazev, S Chang, LS Martin, ... Genome biology 21, 1-13, 2020 | 50 | 2020 |
A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease Y Huang, X Sun, H Jiang, S Yu, C Robins, MJ Armstrong, R Li, Z Mei, ... Nature communications 12 (1), 4472, 2021 | 47 | 2021 |
Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer’s disease J Gockley, KS Montgomery, WL Poehlman, JC Wiley, Y Liu, E Gerasimov, ... Genome medicine 13 (1), 76, 2021 | 39 | 2021 |
Sex differences in brain protein expression and disease AP Wingo, Y Liu, ES Gerasimov, SM Vattathil, J Liu, DJ Cutler, MP Epstein, ... Nature medicine 29 (9), 2224-2232, 2023 | 33 | 2023 |
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder TS Wingo, ES Gerasimov, Y Liu, DM Duong, SM Vattathil, A Lori, ... Molecular psychiatry 27 (7), 3075-3084, 2022 | 28 | 2022 |
Transcriptome-wide association study of post-trauma symptom trajectories identified GRIN3B as a potential biomarker for PTSD development A Lori, K Schultebraucks, I Galatzer-Levy, NP Daskalakis, S Katrinli, ... Neuropsychopharmacology 46 (10), 1811-1820, 2021 | 25 | 2021 |
Antibody response to Lyme disease spirochetes in the context of VlsE-mediated immune evasion AS Rogovskyy, DC Gillis, Y Ionov, E Gerasimov, A Zelikovsky Infection and immunity 85 (1), 10.1128/iai. 00890-16, 2017 | 20 | 2017 |
Identification of surface epitopes associated with protection against highly immune-evasive VlsE-expressing Lyme disease spirochetes M Batool, SEC Caoili, LJ Dangott, E Gerasimov, Y Ionov, H Piontkivska, ... Infection and Immunity 86 (8), 10.1128/iai. 00182-18, 2018 | 12 | 2018 |
Identification of cancer-specific motifs in mimotope profiles of serum antibody repertoire E Gerasimov, A Zelikovsky, I Măndoiu, Y Ionov BMC bioinformatics 18, 1-6, 2017 | 11 | 2017 |
Alzheimer's disease genetic burden is associated with mid‐life depression among persons with normal cognition TS Wingo, ES Gerasimov, SM Canon, JJ Lah, AI Levey, AP Wingo Alzheimer's & Dementia 19 (3), 868-874, 2023 | 10 | 2023 |
Proteomic analysis of Alzheimer’s disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment EB Dammer, A Shantaraman, L Ping, DM Duong, ES Gerasimov, ... Science translational medicine 16 (753), eadn3504, 2024 | 6 | 2024 |
Proteomic Network Analysis of Alzheimer’s Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE ε4 Genotype and Atomoxetine Treatment EB Dammer, A Shantaraman, L Ping, DM Duong, ES Gerasimov, ... medRxiv, 2023 | 5 | 2023 |