Glutaminolysis as a target for cancer therapy L Jin, GN Alesi, S Kang Oncogene 35 (28), 3619-3625, 2016 | 452 | 2016 |
Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ... Cancer cell 27 (2), 257-270, 2015 | 362 | 2015 |
The PLAG1-GDH1 axis promotes anoikis resistance and tumor metastasis through CamKK2-AMPK signaling in LKB1-deficient lung cancer L Jin, J Chun, C Pan, A Kumar, G Zhang, Y Ha, D Li, GN Alesi, Y Kang, ... Molecular cell 69 (1), 87-99. e7, 2018 | 273 | 2018 |
Naringenin as a potential immunomodulator in therapeutics W Zeng, L Jin, F Zhang, C Zhang, W Liang Pharmacological research 135, 122-126, 2018 | 262 | 2018 |
Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis L Jin, J Chun, C Pan, GN Alesi, D Li, KR Magliocca, Y Kang, ZG Chen, ... Oncogene 36 (27), 3797-3806, 2017 | 261 | 2017 |
Prevention of dietary-fat-fueled ketogenesis attenuates BRAF V600E tumor growth S Xia, R Lin, L Jin, L Zhao, HB Kang, Y Pan, S Liu, G Qian, Z Qian, ... Cell metabolism 25 (2), 358-373, 2017 | 183 | 2017 |
Naringenin: a potential immunomodulator for inhibiting lung fibrosis and metastasis G Du, L Jin, X Han, Z Song, H Zhang, W Liang Cancer research 69 (7), 3205-3212, 2009 | 166 | 2009 |
Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling HB Kang, J Fan, R Lin, S Elf, Q Ji, L Zhao, L Jin, JH Seo, C Shan, ... Molecular cell 59 (3), 345-358, 2015 | 158 | 2015 |
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth C Shan, S Elf, Q Ji, HB Kang, L Zhou, T Hitosugi, L Jin, R Lin, L Zhang, ... Molecular cell 55 (4), 552-565, 2014 | 154 | 2014 |
Naringenin reduces lung metastasis in a breast cancer resection model L Qin, L Jin, L Lu, X Lu, C Zhang, F Zhang, W Liang Protein & cell 2 (6), 507-516, 2011 | 128 | 2011 |
PPARα inhibition overcomes tumor-derived exosomal lipid-induced dendritic cell dysfunction X Yin, W Zeng, B Wu, L Wang, Z Wang, H Tian, L Wang, Y Jiang, R Clay, ... Cell reports 33 (3), 2020 | 123 | 2020 |
MAST1 drives cisplatin resistance in human cancers by rewiring cRaf-independent MEK activation L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, ... Cancer cell 34 (2), 315-330. e7, 2018 | 117 | 2018 |
Naringenin ameliorates acute inflammation by regulating intracellular cytokine degradation L Jin, W Zeng, F Zhang, C Zhang, W Liang The Journal of Immunology 199 (10), 3466-3477, 2017 | 112 | 2017 |
Critical role of ASCT2-mediated amino acid metabolism in promoting leukaemia development and progression F Ni, WM Yu, Z Li, DK Graham, L Jin, S Kang, MR Rossi, S Li, ... Nature metabolism 1 (3), 390-403, 2019 | 89 | 2019 |
The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor … D Li, L Jin, GN Alesi, YM Kim, J Fan, JH Seo, D Wang, M Tucker, TL Gu, ... Journal of Biological Chemistry 288 (45), 32528-32538, 2013 | 60 | 2013 |
DGKA provides platinum resistance in ovarian cancer through activation of c-JUN–WEE1 signaling J Li, C Pan, AC Boese, JH Kang, AD Umano, KR Magliocca, W Yang, ... Clinical Cancer Research 26 (14), 3843-3855, 2020 | 51 | 2020 |
Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1 C Pan, JH Kang, JS Hwang, J Li, AC Boese, X Wang, L Yang, TJ Boggon, ... Nature communications 12 (1), 4960, 2021 | 45 | 2021 |
p90RSK2 is essential for FLT3-ITD–but dispensable for BCR-ABL–induced myeloid leukemia S Elf, D Blevins, L Jin, TW Chung, IR Williams, BH Lee, JX Lin, ... Blood, The Journal of the American Society of Hematology 117 (25), 6885-6894, 2011 | 41 | 2011 |
BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers S Khan, J Wiegand, P Zhang, W Hu, D Thummuri, V Budamagunta, N Hua, ... Journal of Hematology & Oncology 15 (1), 23, 2022 | 39 | 2022 |
RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis GN Alesi, L Jin, D Li, KR Magliocca, Y Kang, ZG Chen, DM Shin, FR Khuri, ... Oncogene 35 (41), 5412-5421, 2016 | 39 | 2016 |