The mitochondrial calcium uniporter matches energetic supply with cardiac workload during stress and modulates permeability transition TS Luongo, JP Lambert, A Yuan, X Zhang, P Gross, J Song, ... Cell reports 12 (1), 23-34, 2015 | 413 | 2015 |
The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability TS Luongo, JP Lambert, P Gross, M Nwokedi, AA Lombardi, ... Nature 545 (7652), 93-97, 2017 | 406 | 2017 |
A proliferative burst during preadolescence establishes the final cardiomyocyte number N Naqvi, M Li, JW Calvert, T Tejada, JP Lambert, J Wu, SH Kesteven, ... Cell 157 (4), 795-807, 2014 | 318 | 2014 |
Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease P Jadiya, DW Kolmetzky, D Tomar, A Di Meco, AA Lombardi, JP Lambert, ... Nature communications 10 (1), 3885, 2019 | 286 | 2019 |
Hydrogen sulfide preconditions the db/db diabetic mouse heart against ischemia-reperfusion injury by activating Nrf2 signaling in an Erk-dependent manner BF Peake, CK Nicholson, JP Lambert, RL Hood, H Amin, S Amin, ... American Journal of Physiology-Heart and Circulatory Physiology 304 (9 …, 2013 | 202 | 2013 |
MCUB regulates the molecular composition of the mitochondrial calcium uniporter channel to limit mitochondrial calcium overload during stress JP Lambert, TS Luongo, D Tomar, P Jadiya, E Gao, X Zhang, ... Circulation 140 (21), 1720-1733, 2019 | 135 | 2019 |
Hydrogen sulfide attenuates high fat diet-induced cardiac dysfunction via the suppression of endoplasmic reticulum stress LA Barr, Y Shimizu, JP Lambert, CK Nicholson, JW Calvert Nitric Oxide 46, 145-156, 2015 | 108 | 2015 |
DJ-1 protects the heart against ischemia–reperfusion injury by regulating mitochondrial fission Y Shimizu, JP Lambert, CK Nicholson, JJ Kim, DW Wolfson, HC Cho, ... Journal of molecular and cellular cardiology 97, 56-66, 2016 | 98 | 2016 |
Thioredoxin 1 is essential for sodium sulfide–mediated cardioprotection in the setting of heart failure CK Nicholson, JP Lambert, JD Molkentin, J Sadoshima, JW Calvert Arteriosclerosis, thrombosis, and vascular biology 33 (4), 744-751, 2013 | 72 | 2013 |
Spatial separation of mitochondrial calcium uptake and extrusion for energy-efficient mitochondrial calcium signaling in the heart S De La Fuente, JP Lambert, Z Nichtova, CF Sanz, JW Elrod, SS Sheu, ... Cell reports 24 (12), 3099-3107. e4, 2018 | 66 | 2018 |
Sodium sulfide attenuates ischemic-induced heart failure by enhancing proteasomal function in an Nrf2-dependent manner Y Shimizu, CK Nicholson, JP Lambert, LA Barr, N Kuek, D Herszenhaut, ... Circulation: Heart Failure 9 (4), e002368, 2016 | 65 | 2016 |
Interaction of the Joining Region in Junctophilin-2 With the L-Type Ca2+ Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca2+ Dynamics P Gross, J Johnson, CM Romero, DM Eaton, C Poulet, J Sanchez-Alonso, ... Circulation research 128 (1), 92-114, 2021 | 62 | 2021 |
Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure D Murashige, JW Jung, MD Neinast, MG Levin, Q Chu, JP Lambert, ... Cell metabolism 34 (11), 1749-1764. e7, 2022 | 59 | 2022 |
Hydrogen sulfide provides cardioprotection against myocardial/ischemia reperfusion injury in the diabetic state through the activation of the RISK pathway JP Lambert, CK Nicholson, H Amin, S Amin, JW Calvert Medical gas research 4, 1-11, 2014 | 56 | 2014 |
IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction T Tejada, L Tan, RA Torres, JW Calvert, JP Lambert, M Zaidi, M Husain, ... Proceedings of the National Academy of Sciences 113 (25), 6949-6954, 2016 | 46 | 2016 |
Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia–reperfusion CK Nicholson, JP Lambert, CW Chow, DJ Lefer, JW Calvert Journal of molecular and cellular cardiology 64, 1-10, 2013 | 26 | 2013 |
Altered composition of the mitochondrial Ca2+ uniporter in the failing human heart M Paillard, KT Huang, D Weaver, JP Lambert, JW Elrod, G Hajnóczky Cell Calcium 105, 102618, 2022 | 21 | 2022 |
Exercise training provides cardioprotection by activating and coupling endothelial nitric oxide synthase via a β3-adrenergic receptor-AMP-activated protein kinase signaling pathway LA Barr, JP Lambert, Y Shimizu, LA Barouch, N Naqvi, JW Calvert Medical gas research 7 (1), 1-8, 2017 | 21 | 2017 |
Dysregulation of PINCH signaling in mesial temporal epilepsy C Liu, J Russin, C Heck, K Kawata, R Adiga, W Yen, J Lambert, B Stear, ... Journal of Clinical Neuroscience 36, 43-52, 2017 | 20 | 2017 |
MCUB and mitochondrial calcium uptake–modeling, function, and therapeutic potential JP Lambert, EK Murray, JW Elrod Expert opinion on therapeutic targets 24 (3), 163-169, 2020 | 18 | 2020 |