Harvey W. Smith

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William J. MullerProfessor, McGill UniversityCorreu electrònic verificat a mcgill.ca
Morag ParkProfessor of Oncology and Biochemistry, McGill University, Director Goodman Cancer Research CentreCorreu electrònic verificat a mcgill.ca
Paul SavageGeneral Surgery Resident, University of TorontoCorreu electrònic verificat a mail.utoronto.ca
Vincent GiguereProfessor, McGill UniversityCorreu electrònic verificat a mcgill.ca
Guillaume BourqueProfessor, Human Genetics, McGill UniversityCorreu electrònic verificat a mcgill.ca
Stephen McLaughlinMRC Laboratory of Molecular BiologyCorreu electrònic verificat a mrc-lmb.cam.ac.uk
Dr S.E. JacksonUniversity of CambridgeCorreu electrònic verificat a cam.ac.uk
Michel L. TremblayGoodman Cancer Research Centre Biochemistry McGill UniversityCorreu electrònic verificat a mcgill.ca
Nicholas BertosResearch Associate, Goodman Cancer Research Center, McGill UniversityCorreu electrònic verificat a mcgill.ca
Elaine NganMcGill University Goodman Cancer Research CenterCorreu electrònic verificat a mail.mcgill.ca
Tina GruossoMcGill UniversityCorreu electrònic verificat a mail.mcgill.ca
David P. Labbé, Ph.D., agr., chm.Associate Professor at McGill UniversityCorreu electrònic verificat a mcgill.ca
Simon-Pierre GravelProfesseur agrégé / Associate professor - Faculté de pharmacie, Université de MontréalCorreu electrònic verificat a umontreal.ca
Genevieve DebloisUniversity of Montreal, IRICCorreu electrònic verificat a mail.mcgill.ca
Richard MarcotteNational Research Council CanadaCorreu electrònic verificat a cnrc-nrc.gc.ca
anne-claude gingrasLunenfeld-Tanenbaum Research Institute; University of TorontoCorreu electrònic verificat a lunenfeld.ca
Elena KuzminAssistant Professor, Concordia University; Adjunct Professor, McGill UniversityCorreu electrònic verificat a concordia.ca
Sadiq SalehCorreu electrònic verificat a mail.mcgill.ca
Wontae LeePh.D. candidate, McGill UniversityCorreu electrònic verificat a mail.mcgill.ca
Christopher MoraesCanada Research Chair in Advanced Cellular Microenvironments, McGill UniversityCorreu electrònic verificat a mcgill.ca

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Harvey W. Smith

Rosalind and Morris Goodman Cancer Institute, McGill University

Correu electrònic verificat a mcgill.ca

breast cancer tyrosine kinase signaling epigenetics metabolism targeted therapy resistance


Títol Ordena per cites Ordena per any Ordena per títol	Citada per Citada per	Any
Regulation of cell signalling by uPAR HW Smith, CJ Marshall Nature reviews Molecular cell biology 11 (1), 23-36, 2010	1121	2010
Stimulation of the weak ATPase activity of human hsp90 by a client protein SH McLaughlin, HW Smith, SE Jackson Journal of molecular biology 315 (4), 787-798, 2002	344	2002
uPAR promotes formation of the p130Cas–Crk complex to activate Rac through DOCK180 HW Smith, P Marra, CJ Marshall The journal of cell biology 182 (4), 777-790, 2008	138	2008
ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer G Deblois, HW Smith, IS Tam, SP Gravel, M Caron, P Savage, DP Labbé, ... Nature communications 7 (1), 12156, 2016	126	2016
Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program A Hirukawa, HW Smith, D Zuo, CR Dufour, P Savage, N Bertos, ... Nature communications 9 (1), 2547, 2018	89	2018
LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis E Ngan, K Stoletov, HW Smith, J Common, WJ Muller, JD Lewis, ... Nature communications 8 (1), 15059, 2017	78	2017
Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis R Marcotte, HW Smith, V Sanguin-Gendreau, RV McDonough, WJ Muller Proceedings of the National Academy of Sciences 109 (8), 2808-2813, 2012	58	2012
KIBRA (WWC1) Is a metastasis suppressor gene affected by chromosome 5q loss in triple-negative breast cancer JF Knight, VYC Sung, E Kuzmin, AL Couzens, DA de Verteuil, ... Cell reports 22 (12), 3191-3205, 2018	57	2018
Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy A Hirukawa, S Singh, J Wang, JP Rennhack, M Swiatnicki, ... Cell reports 29 (2), 249-257. e8, 2019	40	2019
Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in … T Rao, JJ Ranger, HW Smith, SH Lam, L Chodosh, WJ Muller Breast Cancer Research 16, 1-14, 2014	38	2014
An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis HW Smith, A Hirukawa, V Sanguin-Gendreau, I Nandi, CR Dufour, D Zuo, ... Nature Communications 10 (1), 2901, 2019	35	2019
Transgenic mouse models—A seminal breakthrough in oncogene research HW Smith, WJ Muller Cold Spring Harbor Protocols 2013 (12), pdb. top069765, 2013	27	2013
Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression I Nandi, HW Smith, V Sanguin-Gendreau, L Ji, A Pacis, V Papavasiliou, ... The Journal of Clinical Investigation 133 (7), 2023	20	2023
An ErbB2 splice variant lacking exon 16 drives lung carcinoma HW Smith, L Yang, C Ling, A Walsh, VD Martinez, J Boucher, D Zuo, ... Proceedings of the National Academy of Sciences 117 (33), 20139-20148, 2020	18	2020
Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer AH Mohammad, SH Kim, N Bertos, W El-Assaad, I Nandi, H Smith, J Yang, ... Molecular Cancer Research 18 (10), 1477-1490, 2020	13	2020
Integration of distinct ShcA signaling complexes promotes breast tumor growth and tyrosine kinase inhibitor resistance JR Ha, R Ahn, HW Smith, V Sabourin, S Hébert, E Cepeda Cañedo, ... Molecular Cancer Research 16 (5), 894-908, 2018	13	2018
Ezh2 promotes mammary tumor initiation through epigenetic regulation of the Wnt and mTORC1 signaling pathways L Liu, B Xiao, A Hirukawa, HW Smith, D Zuo, V Sanguin-Gendreau, ... Proceedings of the National Academy of Sciences 120 (33), e2303010120, 2023	8	2023
Targeting fatty acid oxidation enhances response to HER2-targeted therapy I Nandi, L Ji, HW Smith, D Avizonis, V Papavasiliou, C Lavoie, A Pacis, ... Nature Communications 15 (1), 6587, 2024	5	2024
ARF6 controls RHOB targeting to endosomes regulating cancer cell invasion K Zaoui, HW Smith, M Park, S Duhamel Molecular & Cellular Oncology 7 (5), 1766932, 2020	3	2020
Abstract B007: c-Src and PRC2 activity in ErbB2-driven mammary tumorigenesis and acquired resistance to ErbB2-targeted therapy HW Smith, A Hirukawa, V Sanguin-Gendreau, D Zuo, WJ Muller Molecular Cancer Research 11 (10_Supplement), B007-B007, 2013	2	2013

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