| Structure of the TRPV1 ion channel determined by electron cryo-microscopy M Liao, E Cao, D Julius, Y Cheng Nature 504 (7478), 107-112, 2013 | 1931 | 2013 |
| TRPV1 structures in distinct conformations reveal activation mechanisms E Cao, M Liao, Y Cheng, D Julius Nature 504 (7478), 113-118, 2013 | 1185 | 2013 |
| TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action Y Gao, E Cao, D Julius, Y Cheng Nature 534 (7607), 347-351, 2016 | 890 | 2016 |
| Structural and functional analysis of the costimulatory receptor programmed death-1 X Zhang, JCD Schwartz, X Guo, S Bhatia, E Cao, L Chen, ZY Zhang, ... Immunity 20 (3), 337-347, 2004 | 628 | 2004 |
| TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids E Cao, JF Cordero-Morales, B Liu, F Qin, D Julius Neuron 77 (4), 667-679, 2013 | 385 | 2013 |
| Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2 E Lazar-Molnar, Q Yan, E Cao, U Ramagopal, SG Nathenson, SC Almo Proceedings of the National Academy of Sciences 105 (30), 10483-10488, 2008 | 295 | 2008 |
| The structure of the polycystic kidney disease channel PKD2 in lipid nanodiscs PS Shen, X Yang, PG DeCaen, X Liu, D Bulkley, DE Clapham, E Cao Cell 167 (3), 763-773. e11, 2016 | 294 | 2016 |
| T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface E Cao, X Zang, UA Ramagopal, A Mukhopadhaya, A Fedorov, E Fedorov, ... Immunity 26 (3), 311-321, 2007 | 264 | 2007 |
| Gene Cluster Responsible for Validamycin Biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008 Y Yu, L Bai, K Minagawa, X Jian, L Li, J Li, S Chen, E Cao, T Mahmud, ... Applied and Environmental Microbiology 71 (9), 5066-5076, 2005 | 105 | 2005 |
| Structural mechanisms of transient receptor potential ion channels E Cao Journal of General Physiology 152 (3), e201811998, 2020 | 100 | 2020 |
| NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family E Cao, UA Ramagopal, A Fedorov, E Fedorov, Q Yan, JW Lary, JL Cole, ... Immunity 25 (4), 559-570, 2006 | 91 | 2006 |
| Single particle electron cryo-microscopy of a mammalian ion channel M Liao, E Cao, D Julius, Y Cheng Current opinion in structural biology 27, 1-7, 2014 | 90 | 2014 |
| Structure of CD84 provides insight into SLAM family function Q Yan, VN Malashkevich, A Fedorov, E Fedorov, E Cao, JW Lary, JL Cole, ... Proceedings of the National Academy of Sciences 104 (25), 10583-10588, 2007 | 88 | 2007 |
| The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus K Ha, M Nobuhara, Q Wang, RV Walker, F Qian, C Schartner, E Cao, ... Elife 9, e60684, 2020 | 69 | 2020 |
| Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels W Zheng, X Yang, R Hu, R Cai, L Hofmann, Z Wang, Q Hu, X Liu, ... Nature communications 9 (1), 2302, 2018 | 66 | 2018 |
| Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy X Yang, Q Wang, E Cao Nature communications 11 (1), 1016, 2020 | 63 | 2020 |
| Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide Y Zhao, K Roy, P Vidossich, L Cancedda, M De Vivo, B Forbush, E Cao Nature communications 13 (1), 2747, 2022 | 40 | 2022 |
| Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain TN Vien, J Wang, LCT Ng, E Cao, PG DeCaen Proceedings of the National Academy of Sciences 117 (19), 10329-10338, 2020 | 37 | 2020 |
| Structure of the human cation–chloride cotransport KCC1 in an outward-open state Y Zhao, J Shen, Q Wang, MJ Ruiz Munevar, P Vidossich, M De Vivo, ... Proceedings of the National Academy of Sciences 119 (27), e2109083119, 2022 | 20 | 2022 |
| Structural pharmacology of cation-chloride cotransporters Y Zhao, E Cao Membranes 12 (12), 1206, 2022 | 16 | 2022 |
