Protein mistranslation: friend or foe? LR de Pouplana, MAS Santos, JH Zhu, PJ Farabaugh, B Javid Trends in biochemical sciences 39 (8), 355-362, 2014 | 170 | 2014 |
Pyrazinamide triggers degradation of its target aspartate decarboxylase P Gopal, JP Sarathy, M Yee, P Ragunathan, J Shin, S Bhushan, J Zhu, ... Nature communications 11 (1), 1661, 2020 | 108 | 2020 |
Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair M Ruetz, GC Campanello, M Purchal, H Shen, L McDevitt, H Gouda, ... Science 366 (6465), 589-593, 2019 | 108 | 2019 |
Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription JH Zhu, BW Wang, M Pan, YN Zeng, H Rego, B Javid Nature communications 9 (1), 4218, 2018 | 94 | 2018 |
The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity HW Su, JH Zhu, H Li, RJ Cai, C Ealand, X Wang, YX Chen, TF Zhu, ... Nature microbiology 1 (11), 1-9, 2016 | 85 | 2016 |
Tuberculosis treatment failure associated with evolution of antibiotic resilience Q Liu, J Zhu, CL Dulberger, S Stanley, S Wilson, ES Chung, X Wang, ... Science 378 (6624), 1111-1118, 2022 | 58 | 2022 |
Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation S Chaudhuri, L Li, M Zimmerman, Y Chen, YX Chen, MN Toosky, ... Elife 7, e36782, 2018 | 28 | 2018 |
A mycobacterial systems resource for the research community JA Judd, J Canestrari, R Clark, A Joseph, P Lapierre, ... MBio 12 (2), 10.1128/mbio. 02401-20, 2021 | 27 | 2021 |
Spatiotemporal localization of proteins in mycobacteria J Zhu, ID Wolf, CL Dulberger, HI Won, JC Kester, JA Judd, SE Wirth, ... Cell reports 37 (13), 2021 | 25 | 2021 |
Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity C Akusobi, BS Benghomari, J Zhu, ID Wolf, S Singhvi, CL Dulberger, ... Elife 11, e71947, 2022 | 24 | 2022 |
Mycobacterial nucleoid-associated protein Lsr2 is required for productive mycobacteriophage infection CL Dulberger, CA Guerrero-Bustamante, SV Owen, S Wilson, MG Wuo, ... Nature microbiology 8 (4), 695-710, 2023 | 15 | 2023 |
Clinically relevant mutations in mycobacterial LepA cause rifampicin-specific phenotypic resistance BW Wang, JH Zhu, B Javid Scientific Reports 10 (1), 8402, 2020 | 12 | 2020 |
Uniform and amorphous rifampicin microspheres obtained by freezing induced LLPS during lyophilization C Liu, C Kong, G Wu, J Zhu, B Javid, F Qian International journal of pharmaceutics 495 (1), 500-507, 2015 | 12 | 2015 |
HspX promotes the polar localization of mycobacterial protein aggregates YW Zhang, JH Zhu, ZQ Wang, Y Wu, X Meng, X Zheng, B Javid Scientific Reports 9 (1), 14571, 2019 | 9 | 2019 |
ClpX is essential and activated by single-strand DNA binding protein in mycobacteria JC Kester, O Kandror, T Akopian, MR Chase, J Zhu, EJ Rubin, ... Journal of Bacteriology 203 (4), 10.1128/jb. 00608-20, 2021 | 8 | 2021 |
A mycobacterial systems resource for the research community. mBio 12: e02401-20 JA Judd, J Canestrari, R Clark, A Joseph, P Lapierre, ... | 7 | 2021 |
Pyrazinamide triggers degradation of its target aspartate decarboxylase. Nat Commun 11: 1661 P Gopal, JP Sarathy, M Yee, P Ragunathan, J Shin, S Bhushan, J Zhu, ... | 7 | 2020 |
Peptidyl tRNA hydrolase is required for robust prolyl-tRNA turnover in Mycobacterium tuberculosis FG Tomasi, JTP Schweber, S Kimura, J Zhu, LAT Cleghorn, SH Davis, ... Mbio 14 (1), e03469-22, 2023 | 6 | 2023 |
Targeted protein degradation in mycobacteria uncovers antibacterial effects and potentiates antibiotic efficacy HI Won, S Zinga, O Kandror, T Akopian, ID Wolf, JTP Schweber, ... Nature Communications 15 (1), 4065, 2024 | 5 | 2024 |
CRISPRi–TnSeq maps genome-wide interactions between essential and non-essential genes in bacteria B Jana, X Liu, J Dénéréaz, H Park, D Leshchiner, B Liu, C Gallay, J Zhu, ... Nature microbiology 9 (9), 2395-2409, 2024 | 4 | 2024 |