| The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ... Nature 578 (7793), 94-101, 2020 | 3084 | 2020 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 2513* | 2020 |
| Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor SMA Islam, M Díaz-Gay, Y Wu, M Barnes, R Vangara, EN Bergstrom, ... Cell genomics 2 (11), 2022 | 255 | 2022 |
| SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events EN Bergstrom, MN Huang, U Mahto, M Barnes, MR Stratton, SG Rozen, ... BMC genomics 20, 1-12, 2019 | 229 | 2019 |
| Mechanisms of APOBEC3 mutagenesis in human cancer cells M Petljak, A Dananberg, K Chu, EN Bergstrom, J Striepen, P von Morgen, ... Nature 607 (7920), 799-807, 2022 | 166 | 2022 |
| Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence S Moody, S Senkin, SMA Islam, J Wang, D Nasrollahzadeh, ... Nature Genetics 53 (11), 1553-1563, 2021 | 121 | 2021 |
| Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA EN Bergstrom, J Luebeck, M Petljak, A Khandekar, M Barnes, T Zhang, ... Nature 602 (7897), 510-517, 2022 | 119 | 2022 |
| Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity L Mangiante, N Alcala, A Sexton-Oates, A Di Genova, A Gonzalez-Perez, ... Nature Genetics 55 (4), 607-618, 2023 | 49* | 2023 |
| Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples MH Bailey, WU Meyerson, LJ Dursi, LB Wang, G Dong, WW Liang, ... Nature communications 11 (1), 4748, 2020 | 45 | 2020 |
| APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer JL McCann, A Cristini, EK Law, SY Lee, M Tellier, MA Carpenter, C Beghè, ... Nature Genetics 55 (10), 1721-1734, 2023 | 40* | 2023 |
| Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator EN Bergstrom, M Barnes, I Martincorena, LB Alexandrov BMC bioinformatics 21, 1-10, 2020 | 34 | 2020 |
| Topography of mutational signatures in human cancer B Otlu, M Díaz-Gay, I Vermes, EN Bergstrom, M Zhivagui, M Barnes, ... Cell reports 42 (8), 2023 | 30 | 2023 |
| Geographic variation of mutagenic exposures in kidney cancer genomes S Senkin, S Moody, M Díaz-Gay, B Abedi-Ardekani, T Cattiaux, ... Nature 629 (8013), 910-918, 2024 | 29 | 2024 |
| Examining clustered somatic mutations with SigProfilerClusters EN Bergstrom, M Kundu, N Tbeileh, LB Alexandrov Bioinformatics 38 (13), 3470-3473, 2022 | 19 | 2022 |
| Deep learning artificial intelligence predicts homologous recombination deficiency and platinum response from histologic slides EN Bergstrom, A Abbasi, M Díaz-Gay, L Galland, S Ladoire, SM Lippman, ... Journal of Clinical Oncology 42 (30), 3550-3560, 2024 | 18* | 2024 |
| Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator A Khandekar, R Vangara, M Barnes, M Díaz-Gay, A Abbasi, ... BMC genomics 24 (1), 469, 2023 | 14 | 2023 |
| The Complexity of Tobacco Smoke-Induced Mutagenesis in Head and Neck Cancer L Torrens, S Moody, AC de Carvalho, M Kazachkova, B Abedi-Ardekani, ... medRxiv, 2024.04. 15.24305006, 2024 | 2 | 2024 |
| APOBEC shapes tumor evolution and age at onset of lung cancer in smokers T Zhang, J Sang, PH Hoang, W Zhao, J Rosenbaum, KE Johnson, ... bioRxiv, 2024 | 2 | 2024 |
| Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ... nature genetics 55 (6), 1076-1076, 2023 | 2 | 2023 |
| Synchronous, yet genomically distinct, GIST offer new insights into precise targeting of tumor driver mutations EA Makris, AK Sharma, EN Bergstrom, X Xu, J Torre, S Banerjee, ... JCO Precision Oncology 5, 525-532, 2021 | 2 | 2021 |