Alemayehu (Alex) Gorfe

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John F HancockUniversity of Texas Medial School at HoustonCorreu electrònic verificat a uth.tmc.edu
Priyanka PrakashMcGovern Medical School, University of Texas Health Science Center at HoustonCorreu electrònic verificat a uth.tmc.edu
Prof. J. Andrew McCammonUniversity of California, San DiegoCorreu electrònic verificat a ucsd.edu
Yong ZhouAssociate Professor, McGovern Medical School, University of Texas Health Science CenterCorreu electrònic verificat a uth.tmc.edu
Abdallah Sayyed-AhmadProfessor of Physics, Birzeit UniversityCorreu electrònic verificat a birzeit.edu
Xubo LinAssociate Professor, Beihang UniversityCorreu electrònic verificat a buaa.edu.cn
Barry GrantUniversity of California, San DiegoCorreu electrònic verificat a ucsd.edu
Ilya LeventalUniversity of VirginiaCorreu electrònic verificat a virginia.edu
Lorant JanosiSenior Researcher I, National Institute for Research and Development of Isotopic and Molecular TechnologiesCorreu electrònic verificat a itim-cj.ro
Daniel AbankwaUniversité du LuxembourgCorreu electrònic verificat a uni.lu
Joseph H. LorentUCLouvainCorreu electrònic verificat a uclouvain.be
Kandice R. LeventalUniversity of VirginiaCorreu electrònic verificat a virginia.edu
Suparna Sarkar-BanerjeeScientific Lead-BioImaging, Discovery TechnologyCorreu electrònic verificat a lilly.com
Cynthia V. PagbaUT Health at HoustonCorreu electrònic verificat a uth.tmc.edu
Amedeo CaflischDepartment of Biochemistry, University of ZurichCorreu electrònic verificat a bioc.uzh.ch
Robert G. PartonUniversity of QueenslandCorreu electrònic verificat a imb.uq.edu.au
Amit K GuptaBCM,UPenn,Univ of Florida, Univ of TexasCorreu electrònic verificat a uthscsa.edu
Michael J McCarthyArvinasCorreu electrònic verificat a arvinas.com
L M LichtenbergerCorreu electrònic verificat a uth.edu
Angela SalimThe University of QueenslandCorreu electrònic verificat a uq.edu.au

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Alemayehu (Alex) Gorfe

Altres nomsAlemayehu G Abebe, Alemayehu Gorfe Abebe, Alex Gorfe

Professor, University of Texas McGovern Medical School-Houston

Correu electrònic verificat a uth.tmc.edu - Pàgina d'inici

Protein/Membrane: Simulation and experiment


Títol Ordena per cites Ordena per any Ordena per títol	Citada per Citada per	Any
Structural determinants and functional consequences of protein affinity for membrane rafts JH Lorent, B Diaz-Rohrer, X Lin, K Spring, AA Gorfe, KR Levental, ... Nature communications 8 (1), 1219, 2017	285	2017
Lipid-sorting specificity encoded in K-Ras membrane anchor regulates signal output Y Zhou, P Prakash, H Liang, KJ Cho, AA Gorfe, JF Hancock Cell 168 (1), 239-251. e16, 2017	281	2017
Large conformational changes in proteins: signaling and other functions BJ Grant, AA Gorfe, JA McCammon Current opinion in structural biology 20 (2), 142-147, 2010	280	2010
Ras membrane orientation and nanodomain localization generate isoform diversity D Abankwa, AA Gorfe, K Inder, JF Hancock Proceedings of the National Academy of Sciences 107 (3), 1130-1135, 2010	261	2010
Mapping the nucleotide and isoform-dependent structural and dynamical features of Ras proteins AA Gorfe, BJ Grant, JA McCammon Structure 16 (6), 885-896, 2008	243	2008
Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1, 2-dimyristoylglycero-3-phosphocholine bilayer AA Gorfe, M Hanzal-Bayer, D Abankwa, JF Hancock, JA McCammon Journal of medicinal chemistry 50 (4), 674-684, 2007	222	2007
A novel switch region regulates H‐ras membrane orientation and signal output D Abankwa, M Hanzal‐Bayer, N Ariotti, SJ Plowman, AA Gorfe, RG Parton, ... The EMBO journal 27 (5), 727-735, 2008	211	2008
Polyunsaturated lipids regulate membrane domain stability by tuning membrane order KR Levental, JH Lorent, X Lin, AD Skinkle, MA Surma, EA Stockenbojer, ... Biophysical journal 110 (8), 1800-1810, 2016	208	2016
Ras conformational switching: simulating nucleotide-dependent conformational transitions with accelerated molecular dynamics BJ Grant, AA Gorfe, JA McCammon PLoS computational biology 5 (3), e1000325, 2009	204	2009
Novel allosteric sites on Ras for lead generation BJ Grant, S Lukman, HJ Hocker, J Sayyah, JH Brown, JA McCammon, ... PloS one 6 (10), e25711, 2011	200	2011
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains L Janosi, Z Li, JF Hancock, AA Gorfe Proceedings of the National Academy of Sciences, 2012	185	2012
Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function HJ Hocker, KJ Cho, CYK Chen, N Rambahal, SR Sagineedu, K Shaari, ... Proceedings of the National Academy of Sciences 110 (25), 10201-10206, 2013	166	2013
Ras nanoclusters: molecular structure and assembly D Abankwa, AA Gorfe, JF Hancock Seminars in cell & developmental biology 18 (5), 599-607, 2007	150	2007
Oncogenic K-Ras binds to an anionic membrane in two distinct orientations: a molecular dynamics analysis P Prakash, Y Zhou, H Liang, JF Hancock, AA Gorfe Biophysical journal 110 (5), 1125-1138, 2016	141	2016
Simulating POPC and POPC/POPG bilayers: conserved packing and altered surface reactivity L Janosi, AA Gorfe Journal of chemical theory and computation 6 (10), 3267-3273, 2010	133	2010
Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins K Cho, JH Park, AM Piggott, AA Salim, AA Gorfe, RG Parton, RJ Capon, ... Journal of Biological Chemistry 287 (52), 43573-43584, 2012	115	2012
Functional plasticity in the substrate binding site of β-secretase AA Gorfe, A Caflisch Structure 13 (10), 1487-1498, 2005	112	2005
Computational and biochemical characterization of two partially overlapping interfaces and multiple weak-affinity K-Ras dimers P Prakash, A Sayyed-Ahmad, KJ Cho, DM Dolino, W Chen, H Li, BJ Grant, ... Scientific reports 7 (1), 40109, 2017	106	2017
Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds CS Brand, HJ Hocker, AA Gorfe, CN Cavasotto, CW Dessauer Journal of Pharmacology and Experimental Therapeutics 347 (2), 265-275, 2013	101	2013
The distinct conformational dynamics of K-Ras and H-Ras A59G S Lukman, BJ Grant, AA Gorfe, GH Grant, JA McCammon PLoS computational biology 6 (9), e1000922, 2010	100	2010

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