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Michael R. Lazear
Michael R. Lazear
Belharra Therapeutics
Correu electrònic verificat a scripps.edu - Pàgina d'inici
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Global profiling of lysine reactivity and ligandability in the human proteome
SM Hacker, KM Backus, MR Lazear, S Forli, BE Correia, BF Cravatt
Nature chemistry 9 (12), 1181-1190, 2017
4302017
An activity-guided map of electrophile-cysteine interactions in primary human T cells
EV Vinogradova, X Zhang, D Remillard, DC Lazar, RM Suciu, Y Wang, ...
Cell 182 (4), 1009-1026. e29, 2020
2692020
A proteome-wide atlas of lysine-reactive chemistry
ME Abbasov, ME Kavanagh, TA Ichu, MR Lazear, Y Tao, VM Crowley, ...
Nature chemistry 13 (11), 1081-1092, 2021
1702021
Proteome-wide map of targets of T790M-EGFR-directed covalent inhibitors
S Niessen, MM Dix, S Barbas, ZE Potter, S Lu, O Brodsky, S Planken, ...
Cell chemical biology 24 (11), 1388-1400. e7, 2017
942017
Proteomic discovery of chemical probes that perturb protein complexes in human cells
MR Lazear, JR Remsberg, MG Jaeger, K Rothamel, H Her, KE DeMeester, ...
Molecular cell 83 (10), 1725-1742. e12, 2023
552023
Investigation of a substrate-specifying residue within Papaver somniferum and Catharanthus roseus aromatic amino acid decarboxylases
MP Torrens-Spence, M Lazear, R von Guggenberg, H Ding, J Li
Phytochemistry 106, 37-43, 2014
512014
Sage: an open-source tool for fast proteomics searching and quantification at scale
MR Lazear
Journal of Proteome Research 22 (11), 3652-3659, 2023
432023
Diverse functional evolution of serine decarboxylases: identification of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates
MP Torrens-Spence, R von Guggenberg, M Lazear, H Ding, J Li
BMC plant biology 14, 1-10, 2014
212014
STEREOSELECTIVE COVALENT LIGANDS FOR ONCOGENIC AND IMMUNOLOGICAL PROTEINS
B Cravatt, J Remsberg, M Lazear, M Yokoyama, M Schafroth, ...
US Patent App. 18/712,449, 2025
2025
Open-source and FAIR Research Software for Proteomics
Y Perez-Riverol, W Bittremieux, WS Noble, L Martens, A Bilbao, ...
2024
Function-First Proteomic Strategies for Chemical Probe Discovery in Human Cells
MR Lazear
The Scripps Research Institute, 2022
2022
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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