| A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation BW Ramsey, J Davies, NG McElvaney, E Tullis, SC Bell, P Dřevínek, ... New England Journal of Medicine 365 (18), 1663-1672, 2011 | 2554 | 2011 |
| Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis RG Crystal, NG McElvaney, MA Rosenfeld, CS Chu, A Mastrangeli, ... Nature genetics 8 (1), 42-51, 1994 | 1044 | 1994 |
| Characterization of the inflammatory response to severe COVID-19 illness OJ McElvaney, NL McEvoy, OF McElvaney, TP Carroll, MP Murphy, ... American journal of respiratory and critical care medicine 202 (6), 812-821, 2020 | 714 | 2020 |
| Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. H Nakamura, K Yoshimura, NG McElvaney, RG Crystal The Journal of clinical investigation 89 (5), 1478-1484, 1992 | 637 | 1992 |
| Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial KR Chapman, JGW Burdon, E Piitulainen, RA Sandhaus, N Seersholm, ... The Lancet 386 (9991), 360-368, 2015 | 541 | 2015 |
| Systemic deficiency of glutathione in cystic fibrosis JH Roum, R Buhl, NG McElvaney, Z Borok, RG Crystal Journal of applied physiology 75 (6), 2419-2424, 1993 | 493 | 1993 |
| Protease-antiprotease imbalance in the lungs of children with cystic fibrosis. P Birrer, NG McElvaney, A Rüdeberg, CW Sommer, S Liechti-Gallati, ... American journal of respiratory and critical care medicine 150 (1), 207-213, 1994 | 467 | 1994 |
| Aerosol α1-antitrypsin treatment for cystic fibrosis NG McElvaney, RC Hubbard, P Birrer, RG Crystal, MS Chernick, ... The Lancet 337 (8738), 392-394, 1991 | 437 | 1991 |
| Alpha1-Antitrypsin Deficiency P Strnad, NG McElvaney, DA Lomas New England Journal of Medicine 382 (15), 1443-1455, 2020 | 435 | 2020 |
| Oxidation of either methionine 351 or methionine 358 in α1-antitrypsin causes loss of anti-neutrophil elastase activity C Taggart, D Cervantes-Laurean, G Kim, NG McElvaney, N Wehr, J Moss, ... Journal of Biological Chemistry 275 (35), 27258-27265, 2000 | 433 | 2000 |
| Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing α1-Antitrypsin: Interim Results TR Flotte, BC Trapnell, M Humphries, B Carey, R Calcedo, F Rouhani, ... Human gene therapy 22 (10), 1239-1247, 2011 | 410 | 2011 |
| European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α1-antitrypsin deficiency M Miravitlles, A Dirksen, I Ferrarotti, V Koblizek, P Lange, R Mahadeva, ... European Respiratory Journal 50 (5), 2017 | 363 | 2017 |
| Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant … NG McElvaney, H Nakamura, P Birrer, CA Hebert, WL Wong, M Alphonso, ... The Journal of clinical investigation 90 (4), 1296-1301, 1992 | 353 | 1992 |
| α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8 DA Bergin, EP Reeves, P Meleady, M Henry, OJ McElvaney, TP Carroll, ... The Journal of clinical investigation 120 (12), 4236-4250, 2010 | 344 | 2010 |
| Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α IS Afonina, GA Tynan, SE Logue, SP Cullen, M Bots, AU Lüthi, EP Reeves, ... Molecular cell 44 (2), 265-278, 2011 | 343 | 2011 |
| Innate immunity in cystic fibrosis lung disease D Hartl, A Gaggar, E Bruscia, A Hector, V Marcos, A Jung, C Greene, ... Journal of Cystic Fibrosis 11 (5), 363-382, 2012 | 322 | 2012 |
| α1-Antitrypsin deficiency CM Greene, SJ Marciniak, J Teckman, I Ferrarotti, ML Brantly, DA Lomas, ... Nature reviews Disease primers 2 (1), 1-17, 2016 | 313 | 2016 |
| Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4 JM Devaney, CM Greene, CC Taggart, TP Carroll, SJ O’Neill, ... FEBS letters 544 (1-3), 129-132, 2003 | 297 | 2003 |
| Baseline characteristics of enrollees in the National Heart, Lung and Blood Institute Registry of alpha1-antitrypsin deficiency NG McElvaney, JK Stoller, AS Buist, UBS Prakash Chest 111 (2), 394, 1997 | 297 | 1997 |
| Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding CC Taggart, SA Cryan, S Weldon, A Gibbons, CM Greene, E Kelly, ... The Journal of experimental medicine 202 (12), 1659-1668, 2005 | 292 | 2005 |
