| The diversification of cell death and immunity: memento mori AJ Legrand, M Konstantinou, EF Goode, P Meier Molecular cell 76 (2), 232-242, 2019 | 159 | 2019 |
| Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity P Meier, AJ Legrand, D Adam, J Silke Nature Reviews Cancer 24 (5), 299-315, 2024 | 79 | 2024 |
| RIPK1 and caspase-8 ensure chromosome stability independently of their role in cell death and inflammation G Liccardi, LR Garcia, T Tenev, A Annibaldi, AJ Legrand, D Robertson, ... Molecular cell 73 (3), 413-428. e7, 2019 | 69 | 2019 |
| p53 coordinates base excision repair to prevent genomic instability M Poletto, AJ Legrand, SC Fletcher, GL Dianov Nucleic acids research 44 (7), 3165-3175, 2016 | 66 | 2016 |
| The NUCKS1-SKP2-p21/p27 axis controls S phase entry S Hume, CP Grou, P Lascaux, V D’Angiolella, AJ Legrand, K Ramadan, ... Nature Communications 12 (1), 6959, 2021 | 51 | 2021 |
| Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients X Chen, AJ Legrand, S Cunniffe, S Hume, M Poletto, B Vaz, K Ramadan, ... Cellular Oncology 41, 527-539, 2018 | 43 | 2018 |
| The level of Ets-1 protein is regulated by poly (ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage AJ Legrand, S Choul-Li, C Spriet, T Idziorek, D Vicogne, H Drobecq, ... PloS one 8 (2), e55883, 2013 | 38 | 2013 |
| Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent DNA damage SC Fletcher, CP Grou, AJ Legrand, X Chen, K Soderstrom, M Poletto, ... Nucleic Acids Research 46 (4), 1834-1846, 2018 | 29 | 2018 |
| Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts AJ Legrand, M Poletto, D Pankova, E Clementi, J Moore, F Castro-Giner, ... Oncotarget 9 (17), 13666, 2018 | 22 | 2018 |
| Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells M Poletto, D Yang, SC Fletcher, I Vendrell, R Fischer, AJ Legrand, ... Nucleic acids research 45 (17), 10042-10055, 2017 | 20 | 2017 |
| DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment? M Poletto, AJ Legrand, GL Dianov Current Pharmaceutical Design 23 (32), 4758-4772, 2017 | 16 | 2017 |
| A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death J Mannion, V Gifford, B Bellenie, W Fernando, LR Garcia, R Wilson, ... Immunity, 2024 | 11 | 2024 |
| Ets-1 interacts through a similar binding interface with Ku70 and Poly (ADP-Ribose) Polymerase-1 S Choul-Li, AJ Legrand, B Bidon, D Vicogne, V Villeret, M Aumercier Bioscience, Biotechnology, and Biochemistry 82 (10), 1753-1759, 2018 | 11 | 2018 |
| Poly (ADP-ribose) Polyremase-1 (PARP-1) Inhibition: A Promising Therapeutic Strategy for ETS-Expressing Tumours AJ Legrand, S Choul-Li, V Villeret, M Aumercier International Journal of Molecular Sciences 24 (17), 13454, 2023 | 7 | 2023 |
| Identification de nouveaux partenaires protéiques de l'oncoprotéine Ets-1 et étude de sa régulation par l'enzyme de réparation de l'ADN PARP-1 au sein des cellules tumorales A Legrand Université du Droit et de la Santé-Lille II, 2013 | 1 | 2013 |
| PARP‐1 Inhibition Increases Oxidative Stress in Ets‐1‐Expressing MDA‐MB‐231 Breast Cancer Cells M Hervieu, AJ Legrand, E Floquet, T Idziorek, C Spriet, D Monté, V Villeret, ... Cancer reports 8 (1), e70119, 2025 | | 2025 |
| PARP inhibitors enhance reovirus-mediated cell killing through the death-inducing signaling complex (DISC) with an associated NF-κB-regulated immune response J Kyula-Currie, V Roulstone, J Wright, F Butera, A Legrand, R Elliott, ... bioRxiv, 2023.12. 21.572541, 2023 | | 2023 |
| Talazoparib interacts with oncolytic reovirus to enhance death-inducing signalling complex (DISC)-mediated apoptosis and immune response J Kyula, V Roulstone, R Elliott, H Whittock, G Bozhanova, M McLaughlin, ... Stat 4 (50), 107.103333-126.573333, 2021 | | 2021 |
| Correction: Ets-1 interacts through a similar binding interface with Ku70 and Poly (ADP-Ribose) Polymerase-1 S Choul-Li, AJ Legrand, B Bidon, D Vicogne, V Villeret, M Aumercier Bioscience, Biotechnology and Biochemistry 83 (11), 2175-2175, 2019 | | 2019 |
| PARP-1 regulates Ets-1 transcriptional activity in cancer cells A Legrand, D Vicogne, H Drobecq, V Villeret, M Aumercier FEBS JOURNAL 279, 136-136, 2012 | | 2012 |