| A gene network regulating lysosomal biogenesis and function M Sardiello, M Palmieri, A Di Ronza, DL Medina, M Valenza, ... Science 325 (5939), 473-477, 2009 | 2637 | 2009 |
| Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes C Zuccato, M Tartari, A Crotti, D Goffredo, M Valenza, L Conti, ... Nature genetics 35 (1), 76-83, 2003 | 1181 | 2003 |
| Molecular mechanisms and potential therapeutical targets in Huntington's disease C Zuccato, M Valenza, E Cattaneo Physiological reviews 90 (3), 905-981, 2010 | 1027 | 2010 |
| Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease M Valenza, D Rigamonti, D Goffredo, C Zuccato, S Fenu, L Jamot, ... Journal of Neuroscience 25 (43), 9932-9939, 2005 | 326 | 2005 |
| Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses S Sipione, D Rigamonti, M Valenza, C Zuccato, L Conti, J Pritchard, ... Human molecular genetics 11 (17), 1953-1965, 2002 | 300 | 2002 |
| Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery C Zuccato, D Liber, C Ramos, A Tarditi, D Rigamonti, M Tartari, ... Pharmacological research 52 (2), 133-139, 2005 | 254 | 2005 |
| Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes M Valenza, V Leoni, JM Karasinska, L Petricca, J Fan, J Carroll, ... Journal of Neuroscience 30 (32), 10844-10850, 2010 | 180 | 2010 |
| Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease V Leoni, C Mariotti, SJ Tabrizi, M Valenza, EJ Wild, SMD Henley, ... Brain 131 (11), 2851-2859, 2008 | 166 | 2008 |
| Brain-derived neurotrophic factor in patients with Huntington's disease C Zuccato, M Marullo, B Vitali, A Tarditi, C Mariotti, M Valenza, N Lahiri, ... PLoS One 6 (8), e22966, 2011 | 157 | 2011 |
| Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease Z Xiang, M Valenza, L Cui, V Leoni, HK Jeong, E Brilli, J Zhang, Q Peng, ... Journal of Neuroscience 31 (26), 9544-9553, 2011 | 142 | 2011 |
| Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation M Valenza, JB Carroll, V Leoni, LN Bertram, I Björkhem, RR Singaraja, ... Human molecular genetics 16 (18), 2187-2198, 2007 | 137 | 2007 |
| Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington’s disease M Valenza, V Leoni, A Tarditi, C Mariotti, I Björkhem, S Di Donato, ... Neurobiology of disease 28 (1), 133-142, 2007 | 136 | 2007 |
| Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington’s disease M Valenza, M Marullo, E Di Paolo, E Cesana, C Zuccato, G Biella, ... Cell Death & Differentiation 22 (4), 690-702, 2015 | 127 | 2015 |
| Emerging roles for cholesterol in Huntington's disease M Valenza, E Cattaneo Trends in neurosciences 34 (9), 474-486, 2011 | 127 | 2011 |
| An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin V Lo Sardo, C Zuccato, G Gaudenzi, B Vitali, C Ramos, M Tartari, ... Nature neuroscience 15 (5), 713-721, 2012 | 125 | 2012 |
| Cholesterol‐loaded nanoparticles ameliorate synaptic and cognitive function in H untington's disease mice M Valenza, JY Chen, E Di Paolo, B Ruozi, D Belletti, C Ferrari Bardile, ... EMBO molecular medicine 7 (12), 1547-1564, 2015 | 104 | 2015 |
| Whole body cholesterol metabolism is impaired in Huntington's disease V Leoni, C Mariotti, L Nanetti, E Salvatore, F Squitieri, AR Bentivoglio, ... Neuroscience letters 494 (3), 245-249, 2011 | 101 | 2011 |
| Cholesterol dysfunction in neurodegenerative diseases: is Huntington's disease in the list? M Valenza, E Cattaneo Progress in neurobiology 80 (4), 165-176, 2006 | 92 | 2006 |
| Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease D Goffredo, D Rigamonti, C Zuccato, M Tartari, M Valenza, E Cattaneo Pharmacological research 52 (2), 140-150, 2005 | 66 | 2005 |
| Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators D Rigamonti, D Bolognini, C Mutti, C Zuccato, M Tartari, F Sola, ... Journal of Biological Chemistry 282 (34), 24554-24562, 2007 | 60 | 2007 |
