Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 879 | 2021 |
Etomoxir actions on regulatory and memory T cells are independent of Cpt1a-mediated fatty acid oxidation B Raud, DG Roy, AS Divakaruni, TN Tarasenko, R Franke, EH Ma, ... Cell metabolism 28 (3), 504-515. e7, 2018 | 360 | 2018 |
Targeting DnaN for tuberculosis therapy using novel griselimycins A Kling, P Lukat, DV Almeida, A Bauer, E Fontaine, S Sordello, ... Science 348 (6239), 1106-1112, 2015 | 356 | 2015 |
Industrial natural product chemistry for drug discovery and development A Bauer, M Brönstrup Natural product reports 31 (1), 35-60, 2014 | 309 | 2014 |
Labyrinthopeptins: a new class of carbacyclic lantibiotics K Meindl, T Schmiederer, K Schneider, A Reicke, D Butz, S Keller, ... Angewandte Chemie International Edition 49 (6), 1151-1154, 2010 | 278 | 2010 |
SKAR is a specific target of S6 kinase 1 in cell growth control CJ Richardson, M Bröenstrup, DC Fingar, K Jülich, BA Ballif, S Gygi, ... Current Biology 14 (17), 1540-1549, 2004 | 255 | 2004 |
Antiviral drug discovery: broad-spectrum drugs from nature JP Martinez, F Sasse, M Brönstrup, J Diez, A Meyerhans Natural product reports 32 (1), 29-48, 2015 | 253 | 2015 |
The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications G Férir, MI Petrova, G Andrei, D Huskens, B Hoorelbeke, R Snoeck, ... PloS one 8 (5), e64010, 2013 | 195 | 2013 |
Gold (I) NHC complexes: antiproliferative activity, cellular uptake, inhibition of mammalian and bacterial thioredoxin reductases, and gram‐positive directed antibacterial effects C Schmidt, B Karge, R Misgeld, A Prokop, R Franke, M Brönstrup, I Ott Chemistry–A European Journal 23 (8), 1869-1880, 2017 | 188 | 2017 |
Bifunctional antimicrobial conjugates and hybrid antimicrobials P Klahn, M Brönstrup Natural product reports 34 (7), 832-885, 2017 | 183 | 2017 |
Implementation of proteomic biomarkers: making it work H Mischak, JPA Ioannidis, A Argiles, TK Attwood, E Bongcam‐Rudloff, ... European journal of clinical investigation 42 (9), 1027-1036, 2012 | 182 | 2012 |
Absolute quantification strategies in proteomics based on mass spectrometry M Brönstrup Expert review of proteomics 1 (4), 503-512, 2004 | 162 | 2004 |
HCN Synthesis from Methane and Ammonia: Mechanisms of Pt+-Mediated C−N Coupling M Diefenbach, M Brönstrup, M Aschi, D Schröder, H Schwarz Journal of the American Chemical Society 121 (45), 10614-10625, 1999 | 142 | 1999 |
Platinum dioxide cation: Easy to generate experimentally but difficult to describe theoretically M Brönstrup, D Schröder, I Kretzschmar, H Schwarz, JN Harvey Journal of the American Chemical Society 123 (1), 142-147, 2001 | 136 | 2001 |
Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa R Sommer, S Wagner, K Rox, A Varrot, D Hauck, EC Wamhoff, ... Journal of the American Chemical Society 140 (7), 2537-2545, 2018 | 135 | 2018 |
Ion chemistry of the hexanuclear methoxo-oxovanadium cluster V6O7 (OCH3) 12 D Schröder, M Engeser, M Brönstrup, C Daniel, J Spandl, H Hartl International Journal of Mass Spectrometry 228 (2-3), 743-757, 2003 | 102 | 2003 |
Multivalent siderophore–DOTAM conjugates as theranostics for imaging and treatment of bacterial infections K Ferreira, HY Hu, V Fetz, H Prochnow, B Rais, PP Müller, M Brönstrup Angewandte Chemie International Edition 56 (28), 8272-8276, 2017 | 100 | 2017 |
A Gas‐Phase Model for the Pt+‐Catalyzed Coupling of Methane and Ammonia M Aschi, M Brönstrup, M Diefenbach, JN Harvey, D Schröder, H Schwarz Angewandte Chemie International Edition 37 (6), 829-832, 1998 | 94 | 1998 |
Discovery and Total synthesis of natural cystobactamid derivatives with superior activity against gram‐negative pathogens S Hüttel, G Testolin, J Herrmann, T Planke, F Gille, M Moreno, M Stadler, ... Angewandte Chemie International Edition 56 (41), 12760-12764, 2017 | 91* | 2017 |
Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity P Lukat, Y Katsuyama, S Wenzel, T Binz, C König, W Blankenfeldt, ... Chemical science 8 (11), 7521-7527, 2017 | 89 | 2017 |