Thioflavin T as an efficient inducer and selective fluorescent sensor for the human telomeric G-quadruplex DNA J Mohanty, N Barooah, V Dhamodharan, S Harikrishna, PI Pradeepkumar, ... Journal of the American Chemical Society 135 (1), 367-376, 2013 | 667 | 2013 |
Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook S Shukla, CS Sumaria, PI Pradeepkumar ChemMedChem 5 (3), 328-349, 2010 | 247 | 2010 |
A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H E Zamaratski, PI Pradeepkumar, J Chattopadhyaya Journal of biochemical and biophysical methods 48 (3), 189-208, 2001 | 185 | 2001 |
DNA-catalyzed formation of nucleopeptide linkages PI Pradeepkumar, C Hobartner, DA Baum, SK Silverman ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH- 47 (9), 1753, 2008 | 103 | 2008 |
Selective G-quadruplex DNA stabilizing agents based on bisquinolinium and bispyridinium derivatives of 1, 8-naphthyridine V Dhamodharan, S Harikrishna, C Jagadeeswaran, K Halder, ... The Journal of organic chemistry 77 (1), 229-242, 2012 | 80 | 2012 |
Synthesis of [Ru(phen)2dppz]2+-Tethered Oligo-DNA and Studies on the Metallointercalation Mode into the DNA Duplex D Ossipov, PI Pradeepkumar, M Holmer, J Chattopadhyaya Journal of the American Chemical Society 123 (15), 3551-3562, 2001 | 76 | 2001 |
Specific recognition of promoter G-quadruplex DNAs by small molecule ligands and light-up probes V Dhamodharan, PI Pradeepkumar ACS Chemical Biology 14 (10), 2102-2114, 2019 | 74 | 2019 |
Synthesis, Physicochemical and Biochemical Studies of 1 ‘, 2 ‘-Oxetane Constrained Adenosine and Guanosine Modified Oligonucleotides, and Their Comparison with Those of the … PI Pradeepkumar, P Cheruku, O Plashkevych, P Acharya, S Gohil, ... Journal of the American Chemical Society 126 (37), 11484-11499, 2004 | 68 | 2004 |
Topology specific stabilization of promoter over telomeric G-quadruplex DNAs by bisbenzimidazole carboxamide derivatives V Dhamodharan, S Harikrishna, AC Bhasikuttan, PI Pradeepkumar ACS chemical biology 10 (3), 821-833, 2015 | 65 | 2015 |
Specific Stabilization of c-MYC and c-KIT G-Quadruplex DNA Structures by Indolylmethyleneindanone Scaffolds KV Diveshkumar, S Sakrikar, F Rosu, S Harikrishna, V Gabelica, ... Biochemistry 55 (25), 3571-3585, 2016 | 63 | 2016 |
An Electrochemical Probe of DNA Stacking in an Antisense Oligonucleotide Containing a C3′‐endo‐Locked Sugar EM Boon, JK Barton, PI Pradeepkumar, J Isaksson, C Petit, ... Angewandte Chemie 114 (18), 3552-3555, 2002 | 53 | 2002 |
Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to … PI Pradeepkumar, NV Amirkhanov, J Chattopadhyaya Organic & biomolecular chemistry 1 (1), 81-92, 2003 | 51 | 2003 |
Targeting Promoter G‐Quadruplex DNAs by Indenopyrimidine‐Based Ligands KV Diveshkumar, S Sakrikar, S Harikrishna, V Dhamodharan, ... ChemMedChem 9 (12), 2754-2765, 2014 | 45 | 2014 |
G-quadruplex forming structural motifs in the genome of Deinococcus radiodurans and their regulatory roles in promoter functions S Kota, V Dhamodharan, PI Pradeepkumar, HS Misra Applied microbiology and biotechnology 99, 9761-9769, 2015 | 43 | 2015 |
Synthesis, Gene Silencing, and Molecular Modeling Studies of 4′-C-Aminomethyl-2′-O-methyl Modified Small Interfering RNAs KR Gore, GN Nawale, S Harikrishna, VG Chittoor, SK Pandey, ... The Journal of Organic Chemistry 77 (7), 3233-3245, 2012 | 42 | 2012 |
DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates OY Wong, PI Pradeepkumar, SK Silverman Biochemistry 50 (21), 4741-4749, 2011 | 41 | 2011 |
Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules JB Opalinska, A Kalota, LK Gifford, P Lu, KY Jen, PI Pradeepkumar, ... Nucleic acids research 32 (19), 5791-5799, 2004 | 40 | 2004 |
Oxetane modified antisense oligonucleotides promote RNase H cleavage of the complementary RNA strand in the hybrid duplex as efficiently as the native, and offer improved … PI Pradeepkumar, J Chattopadhyaya Journal of the Chemical Society, Perkin Transactions 2, 2074-2083, 2001 | 38 | 2001 |
Conformation-specific cleavage of antisense oligonucleotide-RNA duplexes by RNase H PI Pradeepkumar, E Zamaratski, A Földesi, J Chattopadhyaya Journal of the Chemical Society, Perkin Transactions 2, 402-408, 2001 | 36 | 2001 |
Site-selective depurination by a periodate-dependent deoxyribozyme C Höbartner, PI Pradeepkumar, SK Silverman Chemical communications, 2255-2257, 2007 | 33 | 2007 |